State MN
Clinical Trials in Minnesota
Minnesota is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Minnesota and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 346 actively recruiting studies with Minnesota sites out of 346 registered in total. The busiest research areas in Minnesota are Breast Cancer, Heart Failure, Ovarian Cancer. Leading sponsors running trials in the state include Mayo Clinic, University of Minnesota, National Cancer Institute (NCI). By stage, Minnesota trials break down as Phase 1 (51), Phase 2 (97), Phase 3 (74), Phase 4 (10).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Minnesota
Frequently Asked Questions — Clinical Trials in Minnesota
How many clinical trials are currently recruiting in Minnesota?
ClinicalMetric currently tracks 346 actively recruiting clinical trials with at least one location in Minnesota. The total number of registered studies—including active but not currently enrolling trials—is 346. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Minnesota?
Minnesota hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Heart Failure, Ovarian Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Minnesota serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Minnesota?
To join a clinical trial in Minnesota, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Minnesota maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Minnesota
NCT06657222 Phase 1, Phase 2
Recruiting
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
Condition
Advanced Solid Tumors
Enrollment
250 pts
Location
United States, Canada, France
Sponsor
Gilead Sciences
NCT06535854 N/A
Recruiting
Prevail Global Study
Condition
Coronary Artery Disease
Enrollment
1,205 pts
Location
United States, Canada, Germany
Sponsor
Medtronic Vascular
NCT05366881 N/A
Recruiting
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and ...
Condition
Brain Cancer
Enrollment
7,000 pts
Location
United States
Sponsor
Adela, Inc
NCT05736471 N/A
Recruiting
Cognitive and Affective Processes Online
Condition
Depression
Enrollment
2,500 pts
Location
United States
Sponsor
University of Minnesota
NCT05938465 Phase 1, Phase 2
Recruiting
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in ...
Condition
Ileal Pouch
Enrollment
50 pts
Location
United States
Sponsor
Exegi Pharma, LLC
NCT06331377 N/A
Recruiting
Clinical and Molecular Characteristics of Histiocytic Disorders
Condition
Histiocytic Disorder
Enrollment
500 pts
Location
United States
Sponsor
Mayo Clinic
NCT07775495 N/A
Recruiting
Observational Study of Decentralized Urine Optical Interaction Patterns Associat...
Condition
Healthy Adult Participants
Enrollment
15 pts
Location
United States
Sponsor
Ecotera Health LLC
NCT06971939 Phase 4
Recruiting
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Includi...
Condition
Macular Telangiectasia Type 2 (MacTel)
Enrollment
234 pts
Location
United States, Australia
Sponsor
Neurotech Pharmaceuticals
NCT06490146 N/A
Recruiting
Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function
Condition
Menopause
Enrollment
100 pts
Location
United States
Sponsor
University of Minnesota
NCT02434003 N/A
Recruiting
Prospective Multicenter Evaluation of a New Predictive Model for the Progression...
Condition
Scoliosis
Enrollment
1,200 pts
Location
United States, Canada, France
Sponsor
St. Justine's Hospital
NCT06892483 N/A
Recruiting
Breastmilk in Response to a Bout of Exercise
Condition
Infant Development
Enrollment
60 pts
Location
United States
Sponsor
Mayo Clinic
NCT05933161 N/A
Recruiting
A Study of Glycemic Control in Left Ventricular Assist
Condition
Type 2 Diabetes Mellitus
Enrollment
20 pts
Location
United States
Sponsor
Mayo Clinic
NCT06548542 Phase 2
Recruiting
Study of Targeted Therapies for the Treatment of Adult Participants With Moderat...
Condition
Crohn's Disease
Enrollment
590 pts
Location
United States, Austria, Belgium
Sponsor
AbbVie
NCT07570654 Phase 2, Phase 3
Recruiting
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COM...
Condition
PTSD - Post Traumatic Stress Disorder
Enrollment
300 pts
Location
United States, Canada
Sponsor
COMPASS Pathways
NCT07365241 Phase 3
Recruiting
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous...
Condition
Small Cell Lung Cancer
Enrollment
531 pts
Location
United States, Austria, Belgium
Sponsor
AbbVie
NCT03866382 Phase 2
Recruiting
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) ...
Condition
Bladder Adenocarcinoma
Enrollment
314 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT07859683 N/A
Recruiting
TMS + Exposure Therapy for Pediatric OCD: Second Phase
Condition
Obsessive Compulsive Behavior
Enrollment
60 pts
Location
United States
Sponsor
Bradley Hospital
NCT06026410 Phase 1
Recruiting
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Condition
Solid Tumors With HRAS Alterations
Enrollment
300 pts
Location
United States, France, Germany
Sponsor
Kura Oncology, Inc.
NCT05919680 Phase 2
Recruiting
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease...
Condition
Intestinal Failure Associated Liver Disease
Enrollment
36 pts
Location
United States
Sponsor
NorthSea Therapeutics B.V.
NCT03739814 Phase 2
Recruiting
Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Pat...
Condition
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Enrollment
84 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT07012135 N/A
Recruiting
Deciphering Preserved Autonomic Function After Multiple Sclerosis
Condition
Multiple Sclerosis
Enrollment
13 pts
Location
United States
Sponsor
Mayo Clinic
Page 14 of 14 — 346 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology