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Recruiting NCT05933161

NCT05933161 A Study of Glycemic Control in Left Ventricular Assist

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Clinical Trial Summary
NCT ID NCT05933161
Status Recruiting
Phase
Sponsor Mayo Clinic
Condition Type 2 Diabetes Mellitus
Study Type OBSERVATIONAL
Enrollment 20 participants
Start Date 2023-11-10
Primary Completion 2027-04

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Freestyle Libre 3 Continuous Glucose Monitor (CGM)

Eligibility Fast-Check

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What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 20 participants in total. It began in 2023-11-10 with a primary completion date of 2027-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study is being conducted to understand if the hemoglobin A1c, a measurement of control of blood sugars over a 3-month time, is valid in patients with Left Ventricular Assist Devices (LVADs) in place. To understand whether it is an adequate measurement, the investigators will compare the A1c to results from a continuous glucose monitor (CGM) measurement of blood sugars. By monitoring blood sugars continuously, the investigators will also assess whether they can get better control of blood sugars with a CGM, including avoiding low blood sugars.

Eligibility Criteria

Inclusion Criteria: * Prior implantation of contemporary, centrifugal flow LVAD (HeartWare or HeartMate 3) at any time after 2010 * Diagnosis of type II diabetes mellitus * Any antihyperglycemic regimen * Greater than 3 months out from LVAD implantation * Capable of utilizing smartphone device for LibreLink app for uploading glycemic data * Patients may be enrolled who have preexisting CGM in place. Exclusion Criteria: * Type I diabetics * Unable to return at 3 month evaluation * Unwillingness to participate

Contact & Investigator

Central Contact

Sarah Schettle, PA-C

✉ Schettle.Sarah@mayo.edu

📞 (507) 293-1375

Principal Investigator

Andrew Rosenbaum, MD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT05933161 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Type 2 Diabetes Mellitus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05933161 currently recruiting?

Yes, NCT05933161 is actively recruiting participants. Contact the research team at Schettle.Sarah@mayo.edu for enrollment information.

Where is the NCT05933161 trial being conducted?

This trial is being conducted at Rochester, United States.

Who is sponsoring the NCT05933161 clinical trial?

NCT05933161 is sponsored by Mayo Clinic. The principal investigator is Andrew Rosenbaum, MD at Mayo Clinic. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology