State TN
Clinical Trials in Tennessee
Tennessee is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Tennessee and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 296 actively recruiting studies with Tennessee sites out of 296 registered in total. The busiest research areas in Tennessee are Breast Cancer, Heart Failure, Colorectal Cancer. Leading sponsors running trials in the state include Vanderbilt University Medical Center, St. Jude Children's Research Hospital, Merck Sharp & Dohme LLC. By stage, Tennessee trials break down as Phase 1 (74), Phase 2 (76), Phase 3 (70), Phase 4 (6).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Tennessee
Frequently Asked Questions — Clinical Trials in Tennessee
How many clinical trials are currently recruiting in Tennessee?
ClinicalMetric currently tracks 296 actively recruiting clinical trials with at least one location in Tennessee. The total number of registered studies—including active but not currently enrolling trials—is 296. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Tennessee?
Tennessee hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Heart Failure, Colorectal Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Tennessee serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Tennessee?
To join a clinical trial in Tennessee, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Tennessee maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Tennessee
NCT05981833 N/A
Recruiting
Dermal Allograft Augmentation of Large and Massive Rotator Cuff Tears
Condition
Full-thickness Rotator Cuff Tear
Enrollment
120 pts
Location
United States
Sponsor
Arthrex, Inc.
NCT06202443 N/A
Recruiting
Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physic...
Condition
Cervical Spine Degeneration
Enrollment
76 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT06311617 N/A
Recruiting
Retinal Vascular Changes During Pregnancy
Condition
Pregnancy
Enrollment
90 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT07406997 N/A
Recruiting
Rehabilitation With Empowered STrategies to Optimize REcovery
Condition
Lumbar Spine Degenerative Changes
Enrollment
100 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT06228326 Phase 1, Phase 2
Recruiting
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies A...
Condition
Lung Cancer, Non-small Cell
Enrollment
250 pts
Location
United States
Sponsor
Krystal Biotech, Inc.
NCT06561685 Phase 1
Recruiting
A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
Condition
Metastatic Solid Tumor
Enrollment
340 pts
Location
United States, France, Germany
Sponsor
Eli Lilly and Company
NCT06747117 N/A
Recruiting
A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus ...
Condition
Lower Extremity Acute Limb Ischemia
Enrollment
300 pts
Location
United States, Australia, Brazil
Sponsor
Penumbra Inc.
NCT06915025 Phase 3
Recruiting
Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combi...
Condition
Epithelial Ovarian Cancer
Enrollment
500 pts
Location
United States
Sponsor
Imunon
NCT04752722 Phase 1, Phase 2
Recruiting
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incom...
Condition
Superficial Bladder Cancer
Enrollment
350 pts
Location
United States, Australia, Canada
Sponsor
enGene, Inc.
NCT07154290 Phase 2
Recruiting
A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adul...
Condition
Non Small Cell Lung Cancer
Enrollment
300 pts
Location
United States
Sponsor
Regeneron Pharmaceuticals
NCT04959097 N/A
Recruiting
Retinoblastoma Patient Clinical Database and Tissue Repository
Condition
Retinoblastoma
Enrollment
800 pts
Location
United States, Canada
Sponsor
Children's Hospital Los Angele
NCT06515613 Phase 1
Recruiting
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other A...
Condition
Platinum-resistant Ovarian Cancer
Enrollment
156 pts
Location
United States, United Kingdom
Sponsor
Context Therapeutics Inc.
NCT06993688 N/A
Recruiting
Revealing Information Genuinely & Honestly Across Time - Communication Preferenc...
Condition
Cancer
Enrollment
85 pts
Location
United States
Sponsor
St. Jude Children's Research H
NCT07754461 Phase 3
Recruiting
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Th...
Condition
Type 2 Diabetes
Enrollment
600 pts
Location
United States, Australia, Canada
Sponsor
Boehringer Ingelheim
NCT06875310 Phase 3
Recruiting
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembr...
Condition
Carcinoma, Non-Small-Cell Lung
Enrollment
630 pts
Location
United States, Argentina, Australia
Sponsor
Mirati Therapeutics Inc.
NCT07277946 N/A
Recruiting
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Saf...
Condition
Hernia
Enrollment
240 pts
Location
United States
Sponsor
Tissium
NCT05753722 Phase 1
Recruiting
A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects Wit...
Condition
Advanced or Metastatic Solid Tumors
Enrollment
270 pts
Location
United States
Sponsor
Incendia Therapeutics
NCT04142437 N/A
Recruiting
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI Duri...
Condition
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Enrollment
150 pts
Location
United States, Argentina, Australia
Sponsor
Bayer
NCT06226272 N/A
Recruiting
Clinical Outcome Measure at Stryker Spine
Condition
Degenerative Disc Disease
Enrollment
5,222 pts
Location
United States
Sponsor
VB Spine, LLC
NCT07253285 Phase 3
Recruiting
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Ado...
Condition
Overweight
Enrollment
460 pts
Location
United States, Australia, Austria
Sponsor
Novo Nordisk A/S
NCT07517263 Phase 3
Recruiting
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to E...
Condition
Cardiovascular Disease and Lipoprotein(a)
Enrollment
5,700 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
NCT04757116 N/A
Recruiting
Post-Market Study to Assess iTind Safety in Comparison to UroLift
Condition
Benign Prostatic Hyperplasia (BPH)
Enrollment
256 pts
Location
United States, United Kingdom
Sponsor
Olympus Corporation of the Ame
NCT07227415 Phase 1, Phase 2
Recruiting
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Al...
Condition
Carcinoma, Renal Cell
Enrollment
224 pts
Location
United States, Australia, China
Sponsor
Pfizer
NCT07674758 N/A
Recruiting
Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification...
Condition
Duchenne Muscular Dystrophy (DMD)
Enrollment
1,000 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT06727604 Phase 2
Recruiting
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatme...
Condition
Graves' Disease
Enrollment
240 pts
Location
United States, Belgium, Georgia
Sponsor
Immunovant Sciences GmbH
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology