State TN
Clinical Trials in Tennessee
Tennessee is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Tennessee and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 312 actively recruiting studies with Tennessee sites out of 312 registered in total. The busiest research areas in Tennessee are Breast Cancer, Endometrial Cancer, Advanced Solid Tumors. Leading sponsors running trials in the state include Vanderbilt University Medical Center, St. Jude Children's Research Hospital, AstraZeneca. By stage, Tennessee trials break down as Phase 1 (80), Phase 2 (93), Phase 3 (93), Phase 4 (12).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Tennessee
Frequently Asked Questions — Clinical Trials in Tennessee
How many clinical trials are currently recruiting in Tennessee?
ClinicalMetric currently tracks 312 actively recruiting clinical trials with at least one location in Tennessee. The total number of registered studies—including active but not currently enrolling trials—is 312. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Tennessee?
Tennessee hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Endometrial Cancer, Advanced Solid Tumors, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Tennessee serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Tennessee?
To join a clinical trial in Tennessee, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Tennessee maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Tennessee
NCT07153614 N/A
Recruiting
Efficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of Che...
Condition
Perioperative Opioid Sparing Techniques
Enrollment
200 pts
Location
United States
Sponsor
University of Tennessee Gradua
NCT07629206 N/A
Recruiting
Post-Marketing Study for Early-Stage Low-Risk Breast Cancer Treatment Using ProS...
Condition
Low-Risk, Early Stage Breast Cancer
Enrollment
400 pts
Location
United States
Sponsor
IceCure Medical Ltd.
NCT07551791 N/A
Recruiting
Suction vs Underwater Seal for HemoPneumoThoraX Trial
Condition
Hemothorax; Traumatic
Enrollment
150 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT07085338 Phase 2
Recruiting
A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunot...
Condition
Neuroblastoma Recurrent
Enrollment
54 pts
Location
United States
Sponsor
St. Jude Children's Research H
NCT02693535 Phase 2
Recruiting
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That...
Condition
Lymphoma, Non-Hodgkin
Enrollment
4,200 pts
Location
United States, Puerto Rico
Sponsor
American Society of Clinical O
NCT06773910 Phase 2
Recruiting
BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lu...
Condition
Limited Stage Small Cell Lung Cancer
Enrollment
250 pts
Location
United States
Sponsor
SCRI Development Innovations,
NCT07066657 Phase 1
Recruiting
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
Condition
Locally Advanced or Metastatic Solid Tumors
Enrollment
572 pts
Location
United States, China
Sponsor
ArriVent BioPharma, Inc.
NCT05999630 Phase 3
Recruiting
Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated Wi...
Condition
Nasolacrimal Duct Obstruction
Enrollment
100 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT07390955 Phase 1
Recruiting
A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS i...
Condition
HIV
Enrollment
83 pts
Location
United States, Peru, Zimbabwe
Sponsor
National Institute of Allergy
NCT06150950 N/A
Recruiting
REHAB Fontan Failure: A Trial of Cardiac Rehabilitation
Condition
Heart Failure Congenital
Enrollment
50 pts
Location
United States
Sponsor
Stanford University
NCT06617325 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Part...
Condition
Systemic Lupus Erythematosus
Enrollment
450 pts
Location
United States, Argentina, Belgium
Sponsor
UCB Biopharma SRL
NCT04079179 Phase 2
Recruiting
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histioc...
Condition
Langerhan's Cell Histiocytosis
Enrollment
90 pts
Location
United States
Sponsor
Carl Allen
NCT06979362 Phase 2
Recruiting
A Research Study Comparing Different Doses of CDR132L With Placebo on the Struct...
Condition
Heart Failure
Enrollment
200 pts
Location
United States, Canada, Germany
Sponsor
Novo Nordisk A/S
NCT06527157 N/A
Recruiting
Investigations of Reproductive Cancers in Women
Condition
Uterine Cancer
Enrollment
4,500 pts
Location
United States
Sponsor
PinkDx, Inc.
NCT06875973 Phase 3
Recruiting
Pelacarsen Roll-over Extension Program
Condition
Atherosclerotic Cardiovascular Disease
Enrollment
599 pts
Location
United States, Puerto Rico
Sponsor
Novartis Pharmaceuticals
NCT05535166 Phase 2
Recruiting
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With...
Condition
Medulloblastoma
Enrollment
130 pts
Location
United States
Sponsor
St. Jude Children's Research H
NCT06241456 Phase 1
Recruiting
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibod...
Condition
Advanced Solid Tumor
Enrollment
351 pts
Location
United States
Sponsor
Fate Therapeutics
NCT05834777 Phase 3
Recruiting
Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor
Condition
Intradialytic Hypotension
Enrollment
26 pts
Location
United States
Sponsor
Vanderbilt University Medical
NCT06885281 Phase 1, Phase 2
Recruiting
A Study of ZL-1310 in Participants With Selected Solid Tumors
Condition
Solid Tumors
Enrollment
166 pts
Location
United States, China
Sponsor
Zai Lab (Shanghai) Co., Ltd.
NCT06932237 N/A
Recruiting
Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans
Condition
Neuro-PASC
Enrollment
200 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT06127407 Phase 3
Recruiting
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chon...
Condition
Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Enrollment
136 pts
Location
United States, Australia, Belgium
Sponsor
Servier Bio-Innovation LLC
NCT06603844 Phase 1, Phase 2
Recruiting
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
Condition
Solid Tumor
Enrollment
156 pts
Location
United States, United Kingdom
Sponsor
Corbus Pharmaceuticals Inc.
NCT03723928 N/A
Recruiting
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Re...
Condition
Anatomic Stage IV Breast Cancer AJCC v8
Enrollment
739 pts
Location
United States, Guam, Puerto Rico
Sponsor
SWOG Cancer Research Network
NCT07160244 Phase 3
Recruiting
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregn...
Condition
Healthy
Enrollment
6,000 pts
Location
United States, Argentina, Brazil
Sponsor
Pfizer
NCT04166409 Phase 3
Recruiting
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients Wit...
Condition
Low Grade Astrocytoma
Enrollment
170 pts
Location
United States, Canada, Puerto Rico
Sponsor
National Cancer Institute (NCI
Page 1 of 13 — 312 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology