State SC
Clinical Trials in South Carolina
South Carolina is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in South Carolina and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 172 actively recruiting studies with South Carolina sites out of 172 registered in total. The busiest research areas in South Carolina are Obesity, Overweight, Acute Myeloid Leukemia. Leading sponsors running trials in the state include Medical University of South Carolina, AstraZeneca, SWOG Cancer Research Network. By stage, South Carolina trials break down as Phase 1 (18), Phase 2 (43), Phase 3 (70), Phase 4 (7).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in South Carolina
Frequently Asked Questions — Clinical Trials in South Carolina
How many clinical trials are currently recruiting in South Carolina?
ClinicalMetric currently tracks 172 actively recruiting clinical trials with at least one location in South Carolina. The total number of registered studies—including active but not currently enrolling trials—is 172. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in South Carolina?
South Carolina hosts clinical trials across a broad range of medical conditions, including Obesity, Overweight, Acute Myeloid Leukemia, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout South Carolina serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in South Carolina?
To join a clinical trial in South Carolina, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in South Carolina maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in South Carolina
NCT07747103 Phase 3
Recruiting
An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North ...
Condition
Hypothyroidism
Enrollment
466 pts
Location
United States
Sponsor
Neuvosyn Laboratories, LLC
NCT06999603 Phase 2
Recruiting
Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respira...
Condition
Viral Pneumonia
Enrollment
550 pts
Location
United States, Belgium, France
Sponsor
Synairgen Research Ltd.
NCT05487664 N/A
Recruiting
RM1 Project 2 - tAN fMRI
Condition
Auricular Stimulation
Enrollment
96 pts
Location
United States
Sponsor
Medical University of South Ca
NCT02523014 Phase 2
Recruiting
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating ...
Condition
Intracranial Meningioma
Enrollment
124 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT03150693 Phase 3
Recruiting
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With N...
Condition
B Acute Lymphoblastic Leukemia
Enrollment
303 pts
Location
United States, Canada
Sponsor
Alliance for Clinical Trials i
NCT05490225 N/A
Recruiting
Access Cannulation Trial II
Condition
Dialysis; Complications
Enrollment
100 pts
Location
United States
Sponsor
Voyager Biomedical
NCT07067463 Phase 3
Recruiting
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Condition
Multiple Sclerosis (MS) Primary Progressive
Enrollment
705 pts
Location
United States, Bulgaria, Croatia
Sponsor
Zenas BioPharma (USA), LLC
NCT05892718 Phase 1
Recruiting
A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pa...
Condition
Advanced Solid Tumor
Enrollment
80 pts
Location
United States, China, Taiwan
Sponsor
FBD Biologics Limited
NCT04715178 N/A
Recruiting
Beat Childhood Cancer Specimen Banking and Data Registry
Condition
Pediatric Cancer
Enrollment
1,000 pts
Location
United States
Sponsor
Giselle Sholler
NCT05943535 Phase 3
Recruiting
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progre...
Condition
Progressive Pulmonary Fibrosis
Enrollment
698 pts
Location
United States, Argentina, Australia
Sponsor
United Therapeutics
NCT03180268 Phase 3
Recruiting
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade...
Condition
Grade 2 Meningioma
Enrollment
163 pts
Location
United States, Canada, India
Sponsor
NRG Oncology
NCT06008197 Phase 3
Recruiting
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mort...
Condition
Heart Failure
Enrollment
5,200 pts
Location
United States, Argentina, Australia
Sponsor
Colorado Prevention Center
NCT07091617 N/A
Recruiting
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing ...
Condition
Miscellaneous Neoplasm, Nos
Enrollment
535 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT06129240 N/A
Recruiting
An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability ...
Condition
Pulmonary Hypertension
Enrollment
80 pts
Location
United States
Sponsor
Liquidia Technologies, Inc.
NCT04718168 N/A
Recruiting
GORE® ENFORM Biomaterial Product Study
Condition
Hernia, Ventral
Enrollment
245 pts
Location
United States
Sponsor
W.L.Gore & Associates
NCT05269316 Phase 1, Phase 2
Recruiting
Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Ad...
Condition
Solid Tumor
Enrollment
61 pts
Location
United States, Australia, China
Sponsor
Impact Therapeutics, Inc.
NCT06616584 Phase 2, Phase 3
Recruiting
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Adva...
Condition
Recurrent Lung Non-Small Cell Carcinoma
Enrollment
378 pts
Location
United States
Sponsor
SWOG Cancer Research Network
NCT06672549 Phase 3
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040...
Condition
Obesity
Enrollment
125 pts
Location
United States, Belgium, Brazil
Sponsor
Eli Lilly and Company
NCT07144150 N/A
Recruiting
EVERO Drug-coated Balloon (DCB) Randomized Trial
Condition
Peripheral Vascular Disease
Enrollment
410 pts
Location
United States
Sponsor
Cook Research Incorporated
NCT05858346 N/A
Recruiting
Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety...
Condition
Social Anxiety Disorder
Enrollment
264 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT07339150 N/A
Recruiting
MiREA-AC for Reducing Problematic Alcohol and Marijuana Use in College Students
Condition
Alcohol Misuse
Enrollment
150 pts
Location
United States
Sponsor
mHealth Systems Inc.
NCT03954574 N/A
Recruiting
Pulmonary Hemodynamics During Exercise - Research Network
Condition
Pulmonary Circulation Diseases
Enrollment
1,500 pts
Location
United States, Australia, Austria
Sponsor
Medical University of Graz
NCT05677490 Phase 3
Recruiting
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanc...
Condition
Advanced Esophageal Adenocarcinoma
Enrollment
382 pts
Location
United States, Puerto Rico
Sponsor
Alliance for Clinical Trials i
NCT03945162 Phase 2
Recruiting
Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Mus...
Condition
Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG
Enrollment
90 pts
Location
United States, Canada
Sponsor
Theralase® Technologies Inc.
NCT07013474 Phase 3
Recruiting
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 W...
Condition
COVID-19 Infection
Enrollment
300 pts
Location
United States, Argentina, Belgium
Sponsor
Pfizer
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology