State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 481 actively recruiting studies with Pennsylvania sites out of 481 registered in total. The busiest research areas in Pennsylvania are Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, National Cancer Institute (NCI). By stage, Pennsylvania trials break down as Phase 1 (77), Phase 2 (124), Phase 3 (115), Phase 4 (15).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 481 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 481. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT06049680 Phase 4
Recruiting
Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in...
Condition
Malnutrition, Child
Enrollment
100 pts
Location
United States
Sponsor
Fresenius Kabi
NCT07056361 N/A
Recruiting
Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement ...
Condition
Movement Disorders (Incl Parkinsonism)
Enrollment
60 pts
Location
United States
Sponsor
Jorge Gonzalez-Martinez
NCT04276870 Phase 2
Recruiting
Orphan Indications for CD19 Redirected Autologous T Cells
Condition
Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL
Enrollment
133 pts
Location
United States
Sponsor
Stephan Grupp MD PhD
NCT05919108 Phase 2
Recruiting
Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
Condition
Anatomic Stage I Breast Cancer
Enrollment
30 pts
Location
United States
Sponsor
Vanderbilt-Ingram Cancer Cente
NCT07243652 N/A
Recruiting
I-DECIDE After Bronchiolitis Hospitalization
Condition
Bronchiolitis Acute
Enrollment
2,700 pts
Location
United States, Canada
Sponsor
Seattle Children's Hospital
NCT03184038 N/A
Recruiting
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurg...
Condition
Metastatic Malignant Neoplasm in the Brain
Enrollment
90 pts
Location
United States
Sponsor
Sidney Kimmel Comprehensive Ca
NCT04715178 N/A
Recruiting
Beat Childhood Cancer Specimen Banking and Data Registry
Condition
Pediatric Cancer
Enrollment
1,000 pts
Location
United States
Sponsor
Giselle Sholler
NCT07723248 Phase 3
Recruiting
A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Pati...
Condition
Metastatic Castration Resistant Prostate Cancer
Enrollment
600 pts
Location
United States, Puerto Rico
Sponsor
ORIC Pharmaceuticals
NCT07704840 Phase 2
Recruiting
A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a...
Condition
Post-Stroke Spasticity
Enrollment
42 pts
Location
United States
Sponsor
Alberto Esquenazi
NCT06240325 N/A
Recruiting
Sleep Promotion Program Primary Care
Condition
Sleep
Enrollment
100 pts
Location
United States
Sponsor
University of Pittsburgh
NCT04561518 N/A
Recruiting
ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-M...
Condition
Transthyretin-Mediated Amyloidosis
Enrollment
1,500 pts
Location
United States, Brazil, Bulgaria
Sponsor
Alnylam Pharmaceuticals
NCT07428538 Phase 3
Recruiting
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With ...
Condition
Hepatitis
Enrollment
350 pts
Location
United States
Sponsor
Bausch Health Americas, Inc.
NCT07586618 Phase 1
Recruiting
First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Har...
Condition
Lymphoblastic Lymphoma
Enrollment
24 pts
Location
United States
Sponsor
Allterum Therapeutics, Inc
NCT04627415 N/A
Recruiting
Project PEAK: Early Intervention for ADHD
Condition
Attention Deficit Hyperactivity Disorder
Enrollment
180 pts
Location
United States
Sponsor
Lehigh University
NCT02693535 Phase 2
Recruiting
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That...
Condition
Lymphoma, Non-Hodgkin
Enrollment
4,200 pts
Location
United States, Puerto Rico
Sponsor
American Society of Clinical O
NCT05314608 N/A
Recruiting
Knee Related Subchondral Bone Lesions Treated With IOBP
Condition
Subchondral Cyst
Enrollment
100 pts
Location
United States
Sponsor
Arthrex, Inc.
NCT07059065 N/A
Recruiting
FIBERGRAFT Aeridyan Posterolateral Fusion Study
Condition
Degenerative Spine Disease
Enrollment
316 pts
Location
United States
Sponsor
DePuy Synthes Products, Inc.
NCT06906367 N/A
Recruiting
A Study of Patients With Fabry Disease (US Specific)
Condition
Fabry Disease
Enrollment
450 pts
Location
United States
Sponsor
Amicus Therapeutics
NCT05966311 N/A
Recruiting
Pediatric Percutaneous Ultrasound Gastrostomy Technique
Condition
Gastrostomy
Enrollment
80 pts
Location
United States
Sponsor
CoapTech
NCT07219771 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarth...
Condition
Knee Osteoarthritis
Enrollment
300 pts
Location
United States, Australia
Sponsor
Doron Therapeutics Inc.
NCT07296484 Phase 2
Recruiting
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Condition
Type 2 Diabetes
Enrollment
1,500 pts
Location
United States
Sponsor
Sparrow Pharmaceuticals
NCT06925321 Phase 3
Recruiting
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult P...
Condition
Invasive Mold Infections
Enrollment
234 pts
Location
United States, Australia, Austria
Sponsor
Basilea Pharmaceutica
NCT07860021 Phase 2, Phase 3
Recruiting
VYVGART (Hytrulo) in Patients With Stiff Person Syndrome (SPS)
Condition
Stiff Person Syndrome
Enrollment
26 pts
Location
United States
Sponsor
Thomas Jefferson University
NCT05442671 N/A
Recruiting
iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for P...
Condition
Pulmonary Hypertension
Enrollment
25 pts
Location
United States
Sponsor
Children's Hospital of Philade
NCT02434393 N/A
Recruiting
Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Pr...
Condition
Major Depression
Enrollment
120 pts
Location
United States
Sponsor
University of Southern Califor
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology