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Clinical Trials in Maryland

Maryland is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Maryland and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 405 actively recruiting studies with Maryland sites out of 405 registered in total. The busiest research areas in Maryland are Breast Cancer, Healthy Volunteers, Obesity. Leading sponsors running trials in the state include Johns Hopkins University, National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID). By stage, Maryland trials break down as Phase 1 (52), Phase 2 (90), Phase 3 (96), Phase 4 (12).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
405
Recruiting Now
405
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Top Conditions in Maryland
Breast Cancer (9)Healthy Volunteers (7)Obesity (7)Stroke (6)HIV (6)Alcohol Use Disorder (5)Major Depressive Disorder (5)Healthy (4)Sickle Cell Disease (4)Depression (4)Asthma (4)Atopic Dermatitis (4)

Frequently Asked Questions — Clinical Trials in Maryland

How many clinical trials are currently recruiting in Maryland?
ClinicalMetric currently tracks 405 actively recruiting clinical trials with at least one location in Maryland. The total number of registered studies—including active but not currently enrolling trials—is 405. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Maryland?
Maryland hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Healthy Volunteers, Obesity, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Maryland serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Maryland?
To join a clinical trial in Maryland, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Maryland maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Maryland

NCT06551116 N/A
Recruiting
QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 i...
Condition
HER2-positive Metastatic Breast Cancer
Enrollment
200 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
View Trial →
NCT06982521 Phase 3
Recruiting
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatme...
Condition
PIK3CA Mutation
Enrollment
540 pts
Location
United States, Argentina, Australia
Sponsor
Relay Therapeutics, Inc.
View Trial →
NCT03843463 Phase 2
Recruiting
Escitalopram and Language Intervention for Subacute Aphasia
Condition
Aphasia
Enrollment
88 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT05389423 Phase 1
Recruiting
Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas
Condition
Diffuse Large Cell Lymphoma
Enrollment
25 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT04853251 Phase 4
Recruiting
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age...
Condition
Neovascular Age-related Macular Degeneration
Enrollment
188 pts
Location
United States
Sponsor
Genentech, Inc.
View Trial →
NCT07672717 Phase 1
Recruiting
Cabotegravir-Hormone PK/PD Interactions for HIV Prevention
Condition
HIV
Enrollment
32 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT03127267 Phase 3
Recruiting
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
Condition
Amyotrophic Lateral Sclerosis
Enrollment
495 pts
Location
United States, Belgium, Denmark
Sponsor
AB Science
View Trial →
NCT06624839 Phase 2
Recruiting
Evaluating Gardasil HPV Vaccine Humoral and Cellular Immune Responses in People ...
Condition
Human Papilloma Virus
Enrollment
120 pts
Location
United States
Sponsor
University of Maryland, Baltim
View Trial →
NCT01425892 N/A
Recruiting
The Pathogenesis and Natural History of Sjogren's Disease
Condition
Sjogren's Syndrome
Enrollment
300 pts
Location
United States
Sponsor
National Institute of Dental a
View Trial →
NCT00005909 N/A
Recruiting
Study of Alkaptonuria
Condition
Alkaptonuria
Enrollment
300 pts
Location
United States
Sponsor
National Human Genome Research
View Trial →
NCT06015893 Phase 2
Recruiting
Semaglutide Therapy for Alcohol Reduction (STAR)
Condition
Addiction
Enrollment
80 pts
Location
United States
Sponsor
National Institute on Drug Abu
View Trial →
NCT00344188 N/A
Recruiting
Diagnosis and Treatment of Leishmania Infections
Condition
Leishmaniasis
Enrollment
289 pts
Location
United States
Sponsor
National Institute of Allergy
View Trial →
NCT05372354 Phase 1, Phase 2
Recruiting
A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-98634...
Condition
Multiple Myeloma
Enrollment
260 pts
Location
United States, Canada, Norway
Sponsor
Bristol-Myers Squibb
View Trial →
NCT06932081 N/A
Recruiting
Adult Congenital Heart Disease International EValuation of the Effectiveness of ...
Condition
Adult Congenital Heart Disease
Enrollment
400 pts
Location
United States, Germany, Netherlands
Sponsor
Leiden University Medical Cent
View Trial →
NCT07227402 Phase 3
Recruiting
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney...
Condition
Renal Cell Carcinoma
Enrollment
904 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT04830137 Phase 1
Recruiting
A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies
Condition
Chronic Lymphocytic Leukemia (CLL)
Enrollment
248 pts
Location
United States
Sponsor
Nurix Therapeutics, Inc.
View Trial →
NCT06587256 Phase 2
Recruiting
Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apn...
Condition
Mild Obstructive Sleep Apnea
Enrollment
100 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT06289686 Phase 4
Recruiting
Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation
Condition
Rotator Cuff Tears
Enrollment
100 pts
Location
United States
Sponsor
Brooke Army Medical Center
View Trial →
NCT04875429 N/A
Recruiting
Zenith® Fenestrated+ Clinical Study
Condition
Aortic Aneurysm, Abdominal
Enrollment
105 pts
Location
United States, United Kingdom
Sponsor
Cook Research Incorporated
View Trial →
NCT02203903 Phase 1
Recruiting
Multi-institutional Prospective Research of Expanded Multi-antigen Specifically ...
Condition
Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS
Enrollment
50 pts
Location
United States
Sponsor
Catherine Bollard
View Trial →
NCT06133972 Phase 3
Recruiting
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participant...
Condition
Systemic Lupus Erythematosus
Enrollment
550 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
View Trial →
NCT07006675 Phase 3
Recruiting
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Frac...
Condition
Tibial Fractures
Enrollment
1,000 pts
Location
United States, Canada
Sponsor
Major Extremity Trauma Researc
View Trial →
NCT06242873 N/A
Recruiting
Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord I...
Condition
Spinal Cord Injuries
Enrollment
20 pts
Location
United States
Sponsor
Hugo W. Moser Research Institu
View Trial →
NCT07089875 Phase 3
Recruiting
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Condition
Gout
Enrollment
500 pts
Location
United States, Poland, Spain
Sponsor
Crystalys Therapeutics
View Trial →
NCT06779773 N/A
Recruiting
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice ...
Condition
Geographic Atrophy
Enrollment
500 pts
Location
United States
Sponsor
Astellas Pharma Global Develop
View Trial →
Page 1 of 17 — 405 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology