State KY
Clinical Trials in Kentucky
Kentucky is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Kentucky and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 135 actively recruiting studies with Kentucky sites out of 135 registered in total. The busiest research areas in Kentucky are Breast Cancer, Ovarian Cancer, Acute Myeloid Leukemia. Leading sponsors running trials in the state include National Cancer Institute (NCI), University of Louisville, AstraZeneca. By stage, Kentucky trials break down as Phase 1 (19), Phase 2 (37), Phase 3 (46), Phase 4 (5).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Kentucky
Frequently Asked Questions — Clinical Trials in Kentucky
How many clinical trials are currently recruiting in Kentucky?
ClinicalMetric currently tracks 135 actively recruiting clinical trials with at least one location in Kentucky. The total number of registered studies—including active but not currently enrolling trials—is 135. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Kentucky?
Kentucky hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Ovarian Cancer, Acute Myeloid Leukemia, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Kentucky serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Kentucky?
To join a clinical trial in Kentucky, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Kentucky maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Kentucky
NCT06721962 Phase 1, Phase 2
Recruiting
Treatment of Moderate to Severe Refractory Crohn's Disease
Condition
Crohns Disease
Enrollment
39 pts
Location
United States
Sponsor
Tr1X, Inc.
NCT04853251 Phase 4
Recruiting
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age...
Condition
Neovascular Age-related Macular Degeneration
Enrollment
188 pts
Location
United States
Sponsor
Genentech, Inc.
NCT07398417 Phase 3
Recruiting
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal ...
Condition
Fibromyalgia
Enrollment
620 pts
Location
United States
Sponsor
Axsome Therapeutics, Inc.
NCT03127267 Phase 3
Recruiting
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
Condition
Amyotrophic Lateral Sclerosis
Enrollment
495 pts
Location
United States, Belgium, Denmark
Sponsor
AB Science
NCT03610763 N/A
Recruiting
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recover...
Condition
Hand Transplantation
Enrollment
180 pts
Location
United States
Sponsor
University of Missouri-Columbi
NCT06843447 Phase 1, Phase 2
Recruiting
A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-590...
Condition
Ovarian Cancer Recurrent
Enrollment
460 pts
Location
United States, Canada, Israel
Sponsor
Merck Sharp & Dohme LLC
NCT07564401 Phase 1, Phase 2
Recruiting
A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy
Condition
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Enrollment
80 pts
Location
United States, Singapore
Sponsor
Novartis Pharmaceuticals
NCT07089875 Phase 3
Recruiting
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Condition
Gout
Enrollment
500 pts
Location
United States, Poland, Spain
Sponsor
Crystalys Therapeutics
NCT04671667 Phase 2
Recruiting
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itse...
Condition
Recurrent Head and Neck Squamous Cell Carcinoma
Enrollment
188 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT05366881 N/A
Recruiting
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and ...
Condition
Brain Cancer
Enrollment
7,000 pts
Location
United States
Sponsor
Adela, Inc
NCT07384975 Phase 2
Recruiting
A Study to Assess NAV-240 in Adult Participants With Hidradenitis Suppurativa
Condition
Hidradenitis Suppurativa (HS)
Enrollment
150 pts
Location
United States
Sponsor
Navigator Medicines, Inc.
NCT07391657 Phase 3
Recruiting
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antig...
Condition
Relapsed Refractory Multiple Myeloma
Enrollment
508 pts
Location
United States, Australia, Brazil
Sponsor
AstraZeneca
NCT05427370 N/A
Recruiting
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C...
Condition
Coronary Artery Disease
Enrollment
754 pts
Location
United States, Austria, Brazil
Sponsor
Sunnybrook Health Sciences Cen
NCT06619990 Phase 1, Phase 2
Recruiting
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Coliti...
Condition
Ulcerative Colitis (UC)
Enrollment
270 pts
Location
United States, Australia, Bulgaria
Sponsor
Xencor, Inc.
NCT07250958 N/A
Recruiting
Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage
Condition
Aneurysmal Subarachnoid Hemorrhage
Enrollment
30 pts
Location
United States
Sponsor
University of Louisville
NCT07382596 Phase 4
Recruiting
Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD
Condition
PTSD
Enrollment
50 pts
Location
United States
Sponsor
Dr. Dean Reeves Clinic
NCT07265479 Phase 3
Recruiting
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participant...
Condition
Atopic Dermatitis
Enrollment
180 pts
Location
United States, Canada
Sponsor
Organon and Co
NCT05775523 N/A
Recruiting
A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatro...
Condition
Growth Hormone Deficiency
Enrollment
500 pts
Location
United States
Sponsor
Ascendis Pharma Endocrinology
NCT03670524 N/A
Recruiting
Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Proje...
Condition
Cardiovascular Diseases
Enrollment
835 pts
Location
United States
Sponsor
University of Louisville
NCT07226596 N/A
Recruiting
Non-Abstinence Outcomes in Methamphetamine Use Disorder
Condition
Methamphetamine Use Disorder
Enrollment
300 pts
Location
United States
Sponsor
William Stoops
NCT06172296 Phase 3
Recruiting
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Tre...
Condition
Ganglioneuroblastoma, Nodular
Enrollment
478 pts
Location
United States, Australia, Canada
Sponsor
National Cancer Institute (NCI
NCT07075159 N/A
Recruiting
Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing
Condition
Wound Healing
Enrollment
20 pts
Location
United States
Sponsor
Janice Hernandez, MD
NCT07186296 N/A
Recruiting
EXoPERT EMERALD Clinical Study
Condition
Breast Cancer
Enrollment
1,400 pts
Location
United States
Sponsor
EXoPERT
NCT06127342 N/A
Recruiting
Exercise and Emotional Learning in Posttraumatic Stress Disorder
Condition
PTSD
Enrollment
100 pts
Location
United States
Sponsor
Christal L Badour
NCT06953674 Phase 3
Recruiting
Saline Versus Balanced Crystalloid in Traumatic Brain Injury
Condition
Traumatic Brain Injury (TBI) Patients
Enrollment
600 pts
Location
United States
Sponsor
University of Louisville
Page 1 of 6 — 135 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology