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anatomic stage iv breast cancer ajcc v8

Total Trials
7
Recruiting Now
7
Trial Phases
Phase 2, Phase 1, Phase 2

Cancer clinical trials represent the largest single category of recruiting studies worldwide, encompassing everything from early-phase safety studies of novel oncology drugs to large Phase 3 comparisons against current standard-of-care chemotherapy regimens. The field has accelerated dramatically with the rise of immunotherapy, targeted therapies, and CAR-T cell treatments that have transformed outcomes for previously untreatable malignancies.

Trials include checkpoint inhibitors (PD-1/PD-L1 agents), KRAS inhibitors, ADC (antibody-drug conjugates), combination chemotherapy regimens, radiation protocols, and surgical technique comparisons. Many trials stratify by biomarker status (PD-L1 expression, TMB, MSI-H) to identify patients most likely to benefit.

The NCI, pharmaceutical sponsors, and academic cancer centers collectively fund thousands of oncology trials annually across every cancer type.

Frequently Asked Questions — anatomic stage iv breast cancer ajcc v8 Clinical Trials

How many clinical trials are currently recruiting for anatomic stage iv breast cancer ajcc v8?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for anatomic stage iv breast cancer ajcc v8, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for anatomic stage iv breast cancer ajcc v8?
anatomic stage iv breast cancer ajcc v8 research spans Phase 1 (1 trial), Phase 2 (5 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a anatomic stage iv breast cancer ajcc v8 clinical trial?
Eligibility criteria for anatomic stage iv breast cancer ajcc v8 trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
5
Top Sponsors
City of Hope Medical Center 1 trial
Yuan Yuan 1 trial
National Cancer Institute (NCI) 1 trial
Roswell Park Cancer Institute 1 trial
ECOG-ACRIN Cancer Research Group 1 trial

Recruiting Clinical Trials

NCT06910761 Phase 2
Recruiting

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Enrollment
35 pts
Location
United States
Sponsor
City of Hope Medical Center
View Trial →
NCT05318469 Phase 1, Phase 2
Recruiting

Ivermectin in Combination With Balstilimab or Pembrolizumab in Patients With Metastatic Triple Negative Breast Cancer

Enrollment
34 pts
Location
United States
Sponsor
Yuan Yuan
View Trial →
NCT05564377 Phase 2
Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Enrollment
2,900 pts
Location
United States, Puert...
Sponsor
National Cancer Institute (NCI...
View Trial →
NCT04348747 Phase 2
Recruiting

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Enrollment
23 pts
Location
United States
Sponsor
Roswell Park Cancer Institute
View Trial →
NCT06112613
Recruiting

Mobile Health for Adherence in Breast Cancer Patients

Enrollment
410 pts
Location
United States, Puert...
Sponsor
ECOG-ACRIN Cancer Research Gro...
View Trial →
NCT03823144
Recruiting

Intravital Microscopy in Human Solid Tumors

Enrollment
85 pts
Location
United States
Sponsor
Mayo Clinic
View Trial →
NCT07112053 Phase 2
Recruiting

A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

Enrollment
40 pts
Location
United States
Sponsor
University of Washington
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology