State AL
Clinical Trials in Alabama
Alabama is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Alabama and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Alabama
Frequently Asked Questions — Clinical Trials in Alabama
How many clinical trials are currently recruiting in Alabama?
ClinicalMetric currently tracks 199 actively recruiting clinical trials with at least one location in Alabama. The total number of registered studies—including active but not currently enrolling trials—is 199. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Alabama?
Alabama hosts clinical trials across a broad range of medical conditions, including Sickle Cell Disease, Breast Cancer, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Alabama serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Alabama?
To join a clinical trial in Alabama, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Alabama maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Alabama
NCT06253117 Phase 2
Recruiting
Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acut...
Condition
Recurrent Acute Pancreatitis
Enrollment
60 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT06745180 N/A
Recruiting
Making Healthy Habits Stick
Condition
Cancer
Enrollment
260 pts
Location
United States
Sponsor
University of Tennessee
NCT06385886 N/A
Recruiting
Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for S...
Condition
Sickle Cell Disease
Enrollment
500 pts
Location
United States
Sponsor
RTI International
NCT04293562 Phase 3
Recruiting
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilterit...
Condition
Acute Myeloid Leukemia
Enrollment
1,186 pts
Location
United States, Australia, Canada
Sponsor
Children's Oncology Group
NCT06867822 Phase 1
Recruiting
Trial of ProAgio in Advanced/Metastatic Colorectal Cancer
Condition
Advanced Colorectal Cancer
Enrollment
27 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT03321045 EARLY_Phase 1
Recruiting
Positron Emission Tomography (PET) Imaging With Zirconium-89 (89Zr)-Trastuzumab ...
Condition
Breast Cancer
Enrollment
10 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05757102 Phase 3
Recruiting
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/V...
Condition
Asthma
Enrollment
292 pts
Location
United States, Argentina, Australia
Sponsor
GlaxoSmithKline
NCT05009992 Phase 2
Recruiting
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Condition
Diffuse Intrinsic Pontine Glioma
Enrollment
360 pts
Location
United States, Australia, Israel
Sponsor
University of California, San
NCT06618287 Phase 1, Phase 2
Recruiting
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Effic...
Condition
Lung Cancer
Enrollment
416 pts
Location
United States, Australia, Canada
Sponsor
Bristol-Myers Squibb
NCT04920136 N/A
Recruiting
Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination ...
Condition
Gingival Recession
Enrollment
20 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT07219771 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarth...
Condition
Knee Osteoarthritis
Enrollment
260 pts
Location
United States, Australia
Sponsor
Doron Therapeutics Inc.
NCT06531863 EARLY_Phase 1
Recruiting
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Condition
Mood Disturbance
Enrollment
64 pts
Location
United States
Sponsor
Auburn University
NCT05788016 N/A
Recruiting
Developing an Opioid Taper Intervention Before Total Joint Arthroplasty
Condition
Arthritis Knee
Enrollment
45 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT06237452 Phase 3
Recruiting
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Condition
Clostridium Difficile
Enrollment
852 pts
Location
United States, Australia, Belgium
Sponsor
Vedanta Biosciences, Inc.
NCT07135284 N/A
Recruiting
Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bron...
Condition
Bronchiectasis Adult
Enrollment
200 pts
Location
United States
Sponsor
Synchrony-Medical, Ltd
NCT06975865 Phase 3
Recruiting
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years Wit...
Condition
Sickle Cell Disease
Enrollment
192 pts
Location
United States, Belgium, Brazil
Sponsor
Sanofi
NCT07174310 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in ...
Condition
Parkinson's Disease
Enrollment
900 pts
Location
United States, Australia, Austria
Sponsor
Hoffmann-La Roche
NCT07201558 Phase 1
Recruiting
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE P...
Condition
Rheumatoid Arthritis
Enrollment
48 pts
Location
United States, Australia, Belgium
Sponsor
AstraZeneca
NCT06297226 Phase 2
Recruiting
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Ther...
Condition
Multiple Myeloma
Enrollment
230 pts
Location
United States, Australia, Canada
Sponsor
Juno Therapeutics, Inc., a Bri
NCT04884035 Phase 1
Recruiting
Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R...
Condition
Lymphoma, B-Cell
Enrollment
224 pts
Location
United States, Australia, Greece
Sponsor
Celgene
NCT05625659 N/A
Recruiting
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breas...
Condition
Breast Cancer
Enrollment
2,032 pts
Location
United States, Canada
Sponsor
American College of Radiology
NCT05636176 Phase 3
Recruiting
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People...
Condition
Heart Failure
Enrollment
5,600 pts
Location
United States, Argentina, Australia
Sponsor
Novo Nordisk A/S
NCT07082738 Phase 2
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Ve...
Condition
Chronic Obstructive Pulmonary Disease (COPD)
Enrollment
987 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT04657068 Phase 1, Phase 2
Recruiting
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Condition
Advanced Cancer
Enrollment
442 pts
Location
United States, France, Spain
Sponsor
Artios Pharma Ltd
NCT05382338 Phase 3
Recruiting
A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hear...
Condition
Childhood Medulloblastoma
Enrollment
225 pts
Location
United States, Canada
Sponsor
Children's Oncology Group
Page 1 of 8 — 199 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology