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State AL

Clinical Trials in Alabama

Alabama is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Alabama and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials

199

Recruiting Now

199

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Top Conditions in Alabama

Sickle Cell Disease (5)Breast Cancer (4)Multiple Myeloma (4)Pancreatic Ductal Adenocarcinoma (3)Kidney Calculi (3)Urolithiasis (3)Urolithiasis, Calcium Oxalate (3)Nephrolithiasis (3)Nephrolithiasis, Calcium Oxalate (3)Oxalate Urolithiasis (3)Healthy (3)Stroke (3)

Frequently Asked Questions — Clinical Trials in Alabama

How many clinical trials are currently recruiting in Alabama?

ClinicalMetric currently tracks 199 actively recruiting clinical trials with at least one location in Alabama. The total number of registered studies—including active but not currently enrolling trials—is 199. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.

What types of clinical trials are available in Alabama?

Alabama hosts clinical trials across a broad range of medical conditions, including Sickle Cell Disease, Breast Cancer, Multiple Myeloma, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Alabama serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.

How do I join a clinical trial near me in Alabama?

To join a clinical trial in Alabama, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Alabama maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Alabama

NCT06682143 N/A

The Effects of Virtual Reality Greenspace on Stress Among Adults With Mobility I...

Mobility Impairments

University of Alabama at Birmi

NCT06051617 Phase 3

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Ci...

Primary Biliary Cholangitis

United States, Argentina, Australia

Gilead Sciences

NCT07198074 Phase 3

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Ca...

Advanced Endometrial Carcinoma

National Cancer Institute (NCI

NCT07288008 N/A

Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety...

Birmingham VA Health Care Syst

NCT06696755 Phase 2

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcapr...

Bipolar I Disorder

NCT06456593 Phase 2

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active...

Moderately to Severely Active Crohn Disease

United States, Belgium, Czechia

NCT06916806 Phase 1

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynam...

Systemic Lupus Erythematosus

United States, Canada, China

NCT04511078 Phase 2

Phase II Panitumumab-IRDye800 in Head & Neck Cancer

Head and Neck Cancer

University of Alabama at Birmi

NCT02397668 N/A

CorMatrix Cor TRICUSPID ECM Valve Replacement Study

Tricuspid Valve Disease

Corvivo Cardiovascular, Inc.

NCT07000084 Phase 3

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BC...

Recurrent Non-Muscle Invasive Bladder Carcinoma

Alliance for Clinical Trials i

NCT06683092 N/A

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

Cystic Fibrosis

Boston Children's Hospital

NCT06562192 Phase 1

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and ...

Pancreatic Ductal Adenocarcinoma

United States, Belgium, Canada

Novartis Pharmaceuticals

NCT05461326 N/A

Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction ...

Orthopedic Disorder

University of Alabama at Birmi

NCT05850234 Phase 1, Phase 2

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

Relapsed/Refractory Multiple Myeloma

NCT04154332 N/A

Exosome Cargo From Preeclampsia Patients

University of Alabama at Birmi

NCT06832007 N/A

The Effect of Light Intervention on Recovery in Individuals With Opioid Use Diso...

Opioid Use Disorder

University of Alabama at Birmi

NCT06272045 N/A

Early Intervention to Promote Cardiovascular Health of Mothers and Children

Cardiovascular Health

JHSPH Center for Clinical Tria

NCT06503731 Phase 2

A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by...

Antibody-mediated Rejection

United States, Austria, Belgium

NCT07041489 N/A

Evaluating the Combined Use of Supplement and Serum in Promoting Hair Growth in ...

The Center for Clinical and Co

NCT06173323 N/A

A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chr...

Decision Making, Shared

University of Alabama at Birmi

NCT06907979 N/A

Cannabis and Processing Emotions Study

Cannabis Use Disorder, Severe

Auburn University

NCT06701682 Phase 2

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilob...

Acute Respiratory Distress Syndrome (ARDS)

PPD Development, LP

NCT06099769 Phase 2

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemo...

Metastatic Breast Cancer

Memorial Sloan Kettering Cance

NCT06331546 N/A

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

University of Alabama at Birmi

NCT06318169 Phase 3

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With ...

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

United States, Argentina, Australia

Page 2 of 8 — 199 trials total

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology