SPONSOR

VA Office of Research and Development

Total Trials

Recruiting

Phases

Phase 4, Phase 3, Phase 2

Conditions studied: Aging Musculoskeletal Diseases Osteoporosis Spinal Cord Injuries Depression Depressive Disorder, Major Neuro-PASC Long COVID Sleep Apnea Syndrome Obstructive Sleep Apnea

VA Office of Research and Development is a clinical research sponsor with 38 registered studies on ClinicalTrials.gov, of which 38 are actively recruiting participants. Research covers conditions including Aging, Musculoskeletal Diseases, Osteoporosis, Spinal Cord Injuries.

The trial portfolio spans Phase 4, Phase 3, Phase 2 studies, reflecting a pipeline that may include early-stage safety evaluations, mid-stage efficacy assessments, and large-scale confirmatory trials. All studies listed here are sourced directly from ClinicalTrials.gov and updated daily.

Frequently Asked Questions — VA Office of Research and Development

How many clinical trials has VA Office of Research and Development sponsored?

ClinicalMetric currently tracks 38 clinical trials sponsored by VA Office of Research and Development, of which 38 are actively recruiting participants. These trials cover conditions including Aging, Musculoskeletal Diseases, Osteoporosis. Trial counts are updated daily from ClinicalTrials.gov and reflect currently registered studies.

What therapeutic areas does VA Office of Research and Development research focus on?

VA Office of Research and Development clinical trials span Aging, Musculoskeletal Diseases, Osteoporosis, Spinal Cord Injuries, Depression, and additional conditions. The research pipeline includes Phase 4, Phase 3, Phase 2 trials, reflecting work from early-stage safety evaluation through large-scale efficacy studies.

How do I participate in a VA Office of Research and Development clinical trial?

To participate in a VA Office of Research and Development trial, review the active studies listed on this page, check each trial's specific eligibility criteria on ClinicalTrials.gov, and contact the trial site directly—not the sponsor's headquarters. Trial sites are academic medical centers, hospitals, or specialized research clinics. Your physician can facilitate a referral. ClinicalMetric lists all VA Office of Research and Development trials with current recruitment status updated daily.

VA Office of Research and Development

Frequently Asked Questions — VA Office of Research and Development

Clinical Trials by VA Office of Research and Development

Mode of Exercise and Bone Biomarkers in Older Veterans

Dosing rTMS for Depression Post-SCI

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

Increasing Veterans' Social Engagement and Connectedness

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease

The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

MetfOrmin BenefIts Lower Extremities With Intermittent Claudication

Pharmacogenomic Informed Statin Prescribing

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

Suicide Risk Interventions

Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder

A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation

Developing and Testing a Trauma-Informed Exercise Intervention for Women Veterans With Histories of Sexual Violence

Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder

COPEWeb Training for Providers

Empagliflozin Treatment in Kidney Transplant Recipients

Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

Predictors of Post-COVID-19 Clinical and Cognitive Consequences

Non-invasive VNS for Parkinson's Gait

NAFLD Clinical Care Pathway

Spinal Neurorehabilitation for Veterans With SCI

Fall Risk Identification and Management for Older Veterans

Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness

VA Transitional Pain Service Study

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult Veterans

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

A Study to Improve Skeletal Muscle in Veterans With HIV

Impact of Improving Footwear Options

HealthyTogether: RCT of a Dyadic Weight Management Intervention

Pimavanserin for Insomnia in Veterans With PTSD