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obstructive sleep apnea

Total Trials
26
Recruiting Now
26
Trial Phases
Various

ClinicalMetric tracks all active clinical trials for obstructive sleep apnea sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — obstructive sleep apnea Clinical Trials

How many clinical trials are currently recruiting for obstructive sleep apnea?
ClinicalMetric currently tracks 26 actively recruiting clinical trials for obstructive sleep apnea, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 26. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for obstructive sleep apnea?
obstructive sleep apnea research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a obstructive sleep apnea clinical trial?
Eligibility criteria for obstructive sleep apnea trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
VA Office of Research and Development 3 trials
Washington University School of Medicine 2 trials
Fondazione Don Carlo Gnocchi ETS 1 trial
University of Pennsylvania 1 trial
Kaohsiung Armed Forces General Hospital 1 trial

Recruiting Clinical Trials

NCT06664450
Recruiting
Brain Fog in Sleep Apnea
Enrollment
80 pts
Location
Italy
Sponsor
Fondazione Don Carlo Gnocchi E...
View Trial →
NCT06189755
Recruiting
MicroRNAs as Biomarkers for Obstructive Sleep Apnea
Enrollment
500 pts
Location
United States, Icela...
Sponsor
University of Pennsylvania
View Trial →
NCT07603583
Recruiting
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
Enrollment
100 pts
Location
Taiwan
Sponsor
Kaohsiung Armed Forces General...
View Trial →
NCT07074288
Recruiting
Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives
Enrollment
60 pts
Location
United States
Sponsor
Washington University School o...
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NCT06314477
Recruiting
Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial
Enrollment
138 pts
Location
Spain
Sponsor
Hospital Clinic of Barcelona
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NCT04179981
Recruiting
Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
Enrollment
668 pts
Location
United States
Sponsor
VA Office of Research and Deve...
View Trial →
NCT06803095
Recruiting
Efficacy of Walking Exercise With Dog on Tinnitus Complaints in Sleep Apnea (Obstructive Sleep Apnea)
Enrollment
40 pts
Location
Egypt
Sponsor
Cairo University
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NCT05350332
Recruiting
Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy
Enrollment
151 pts
Location
United States
Sponsor
Emory University
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NCT07220525
Recruiting
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Enrollment
100 pts
Location
United States
Sponsor
University of California, San ...
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NCT07303452
Recruiting
Evaluation of the Restera™ Serene™ System in Adults With Obstructive Sleep Apnea
Enrollment
20 pts
Location
Australia
Sponsor
Restera, Inc.
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NCT06471751
Recruiting
Strengthening Inspiratory and Oropharyngeal Muscles in Moderate Obstructive Sleep Apnea Hypopnea Syndrome
Enrollment
38 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
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NCT04623463
Recruiting
Effects of Physical Activity on OSA Severity Based on the Level of Fluid Shift
Enrollment
62 pts
Location
France
Sponsor
University Hospital, Grenoble
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NCT07090395
Recruiting
Severe Label Expansion for EVO Products Trial
Enrollment
49 pts
Location
United States
Sponsor
ProSomnus Sleep Technologies
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NCT06291870
Recruiting
Predictors of Post-COVID-19 Clinical and Cognitive Consequences
Enrollment
200 pts
Location
United States
Sponsor
VA Office of Research and Deve...
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NCT02410850
Recruiting
Long Term Oral Appliance Therapy Effectiveness for Obstructive Sleep Apnea Syndrome
Enrollment
1,000 pts
Location
Canada
Sponsor
University of British Columbia
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NCT07785999
Recruiting
CES-EES Clinical Score and a Wearable Ring Sensor for Obstructive Sleep Apnea: Individual and Combined Validation Against In-Laboratory Polysomnography
Enrollment
58 pts
Location
Malaysia
Sponsor
University of Malaya
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NCT06621511
Recruiting
OurSleepKit To Support CPAP Adherence
Enrollment
360 pts
Location
United States
Sponsor
National Heart, Lung, and Bloo...
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NCT06264427
Recruiting
Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
Enrollment
1,000 pts
Location
Greenland
Sponsor
Steno Diabetes Center Greenlan...
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NCT06239883
Recruiting
This Research Project Studies the Relationship Between OSA and Nocturia.
Enrollment
100 pts
Location
Czechia
Sponsor
University Hospital Ostrava
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NCT06317701
Recruiting
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
Enrollment
30 pts
Location
United States
Sponsor
University of Chicago
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NCT02762175
Recruiting
3D Volumetric Changes in the Upper Airway After MMA in OSAS Patients and the Implication on QOL: A Prospective Registry
Enrollment
150 pts
Location
Belgium
Sponsor
AZ Sint-Jan AV
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NCT05986487
Recruiting
Impact of Sleep-Disordered Breathing Management in Systemic Hypertension Control: METASLEEP Project
Enrollment
1,523 pts
Location
Spain
Sponsor
Sociedad Española de Neumologí...
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NCT07132307
Recruiting
Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement
Enrollment
30 pts
Location
United States
Sponsor
Washington University School o...
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NCT02703207
Recruiting
Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
Enrollment
108 pts
Location
United States
Sponsor
VA Office of Research and Deve...
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NCT07273019
Recruiting
Tongue Muscular Assessment in Children With Sleep Disordered Breathing
Enrollment
78 pts
Location
France
Sponsor
Hospices Civils de Lyon
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NCT06030349
Recruiting
Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome
Enrollment
200 pts
Location
Ireland, United King...
Sponsor
Children's Health Ireland
View Trial →

Related Conditions

hypertension (2) quality of life (2) asthma (1) sleep apnea syndrome (1) copd (1) overlap syndrome (1) neurocognitive function (1) sleepiness (1) elderly (1) positive airway pressure (1) tinnitus subjective (1) premature ventricular contraction pvc (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology