Medical Condition

amputation

Total Trials

8

Recruiting Now

8

Trial Phases

Phase 1, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for amputation sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — amputation Clinical Trials

How many clinical trials are currently recruiting for amputation?

ClinicalMetric currently tracks 8 actively recruiting clinical trials for amputation, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for amputation?

amputation research spans Phase 1 (1 trial), Phase 2 (1 trial), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a amputation clinical trial?

Eligibility criteria for amputation trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 3

Top Sponsors

University of Utah 1 trial

University of Michigan 1 trial

Shirley Ryan AbilityLab 1 trial

University of Colorado, Denver 1 trial

Johns Hopkins University 1 trial

Recruiting Clinical Trials

NCT05505513

Recruiting

Can an Array of Micro-electrodes Implanted in a Human Nerve Record Neural Signals and Provide Feedback?

Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs

University of Michigan

View Trial →

NCT06433648

Recruiting

Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait

Shirley Ryan AbilityLab

View Trial →

NCT07263945 Phase 1

Recruiting

Influence of Prosthetic Foot Stiffness on Transtibial Osseointegrated Bone-Anchored Limb Outcomes

University of Colorado, Denver

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NCT02395497 Phase 2, Phase 3

Recruiting

Human Penile Allotransplantation

Johns Hopkins University

View Trial →

NCT06908538

Recruiting

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

Assessing Ambulatory and Non-ambulatory Community Mobility in People With Lower Limb Amputation

Virginia Commonwealth Universi...

View Trial →

NCT06937242

Recruiting

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

Hanger Institute for Clinical ...

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Related Conditions

amputation traumatic (2) amputation traumatic surgery (2) amputation of knee (1) amputation traumatic limb (1) transtibial amputation unilateral (1) bone anchored devices (1) osseointegration (1) wounds and injuries (1) urologic surgical procedures male (1) penis transplantation (1) penis surgery (1) penis injuries (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology