Browse by Phase
Phase 1 / Phase 2 Clinical Trials
Phase 1/2 combined trials evaluate both safety (Phase 1) and preliminary efficacy (Phase 2) in a single study protocol, often used to accelerate early development.
Total Trials
374
Recruiting Now
374
Top Conditions in Phase 1 / Phase 2
NCT06110403 Phase 1, Phase 2
Recruiting
Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation,...
Condition
Copd
Enrollment
35 pts
Location
France
Sponsor
University Hospital, Lille
NCT06421831 Phase 1, Phase 2
Recruiting
Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spina...
Condition
Spinal Muscular Atrophy Type 3
Enrollment
21 pts
Location
China
Sponsor
GeneCradle Inc
NCT04715022 Phase 1, Phase 2
Recruiting
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C St...
Condition
Hypertension
Enrollment
23 pts
Location
United States
Sponsor
University of Kansas Medical C
NCT06408337 Phase 1, Phase 2
Recruiting
Phase I-IIa, to Evaluate the Safety, Feasibility, and Efficacy of the Use of BIO...
Condition
Cleft Lip and Palate
Enrollment
15 pts
Location
Spain
Sponsor
Elisa María Cubiles Montero de
NCT06139211 Phase 1, Phase 2
Recruiting
A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors
Condition
Advanced Solid Tumor
Enrollment
186 pts
Location
China
Sponsor
Shanghai Junshi Bioscience Co.
NCT06431165 Phase 1, Phase 2
Recruiting
Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative P...
Condition
Perioperative Pain Management
Enrollment
69 pts
Location
Egypt
Sponsor
Cairo University
NCT03167437 Phase 1, Phase 2
Recruiting
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerat...
Condition
Crohn's Disease
Enrollment
35 pts
Location
United States
Sponsor
National Institute of Allergy
NCT05905328 Phase 1, Phase 2
Recruiting
Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Recei...
Condition
Cytokine Release Syndrome
Enrollment
54 pts
Location
United States
Sponsor
CytoAgents, Inc.
NCT04263831 Phase 1, Phase 2
Recruiting
Low Dose IL-2 for the Treatment of Crohn's Disease
Condition
Crohn Disease
Enrollment
30 pts
Location
United States
Sponsor
Boston Children's Hospital
NCT05702853 Phase 1, Phase 2
Recruiting
Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With C...
Condition
B-cell Non Hodgkin Lymphoma
Enrollment
27 pts
Location
United States
Sponsor
Medical University of South Ca
NCT06199531 Phase 1, Phase 2
Recruiting
Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency
Condition
NGLY1 Deficiency
Enrollment
6 pts
Location
United States
Sponsor
Grace Science, LLC
NCT06926075 Phase 1, Phase 2
Recruiting
Early Phase Study of KESONOTIDE™in Participants With Solid Tumours
Condition
Prostate Cancers
Enrollment
80 pts
Location
Australia
Sponsor
Filamon LTD
NCT05765812 Phase 1, Phase 2
Recruiting
A Study of Debio 0123 in Combination With Temozolomide in Adult Participants Wit...
Condition
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Enrollment
116 pts
Location
United States, Spain, Switzerland
Sponsor
Debiopharm International SA
NCT06025630 Phase 1, Phase 2
Recruiting
Targeting Endoplasmic Reticulum Stress in Human Hypertension
Condition
Hypertension
Enrollment
70 pts
Location
United States
Sponsor
University of North Texas Heal
NCT05759728 Phase 1, Phase 2
Recruiting
A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subje...
Condition
Colorectal Cancer Metastatic
Enrollment
45 pts
Location
Australia
Sponsor
Carina Biotech Limited
NCT07007559 Phase 1, Phase 2
Recruiting
ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Adv...
Condition
Breast Cancer, Metastatic
Enrollment
80 pts
Location
United States
Sponsor
ALX Oncology Inc.
NCT05559879 Phase 1, Phase 2
Recruiting
Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma
Condition
Gynecologic Cancer
Enrollment
37 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05345418 Phase 1, Phase 2
Recruiting
Umbilical Cord-Derived Mesenchymal Stem Cell (VCELL 1) for Male Patients With Se...
Condition
Sexual Dysfunction Male
Enrollment
158 pts
Location
Vietnam
Sponsor
Vinmec Research Institute of S
NCT05300282 Phase 1, Phase 2
Recruiting
Study of Atezolizumab Plus BEGEV Regimen in Relapsed or Refractory Hodgkin's Lym...
Condition
Relapsed or Refractory Hodgkin's Lymphoma
Enrollment
122 pts
Location
Italy
Sponsor
Fondazione Italiana Linfomi -
NCT07288359 Phase 1, Phase 2
Recruiting
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Pa...
Condition
Advanced HR+/HER2- Breast Cancer
Enrollment
205 pts
Location
United States, Japan, Singapore
Sponsor
Novartis Pharmaceuticals
NCT07111520 Phase 1, Phase 2
Recruiting
A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 a...
Condition
Non-small Cell Lung Cancer
Enrollment
420 pts
Location
United States, Moldova
Sponsor
BioNTech SE
NCT06667960 Phase 1, Phase 2
Recruiting
Study of JK06 in Patients With Unresectable Locally Advanced or Metastatic Cance...
Condition
Solid Tumor
Enrollment
255 pts
Location
Belgium, Spain
Sponsor
Salubris Biotherapeutics Inc
NCT07002320 Phase 1, Phase 2
Recruiting
Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-re...
Condition
Metastatic Castrate-Resistant Prostate Cancer (mCRPC)
Enrollment
78 pts
Location
Switzerland, United Kingdom
Sponsor
Institute of Cancer Research,
NCT07344194 Phase 1, Phase 2
Recruiting
Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and ...
Condition
Essential Tremor
Enrollment
36 pts
Location
Brazil
Sponsor
São Paulo State University
NCT06754605 Phase 1, Phase 2
Recruiting
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Recombinan...
Condition
Respiratory Syncytial Virus
Enrollment
480 pts
Location
China
Sponsor
Sinocelltech Ltd.