Browse by Phase
Phase 1 / Phase 2 Clinical Trials
Phase 1/2 combined trials evaluate both safety (Phase 1) and preliminary efficacy (Phase 2) in a single study protocol, often used to accelerate early development.
Total Trials
361
Recruiting Now
361
Top Conditions in Phase 1 / Phase 2
NCT05187429 Phase 1, Phase 2
Recruiting
Low Dose Nivolumab in Adults Living With HIV on Antiretroviral Therapy
Condition
HIV I Infection
Enrollment
42 pts
Location
Australia, Singapore
Sponsor
University of Melbourne
NCT07477912 Phase 1, Phase 2
Recruiting
Anti BCMA CAR- T Cell Therapy for Adults With Relapsed or Refractory Multiple My...
Condition
Multiple Myeloma Refractory
Enrollment
30 pts
Location
Belarus
Sponsor
Minsk Scientific-Practical Cen
NCT06759181 Phase 1, Phase 2
Recruiting
Safety and Efficacy of Anti-BCMA/FcRL5 CAR-T Cell Therapy in Treating Relapsed a...
Condition
Multiple Myeloma
Enrollment
20 pts
Location
China
Sponsor
Xuzhou Medical University
NCT05944224 Phase 1, Phase 2
Recruiting
A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cad...
Condition
Advanced Solid Tumors
Enrollment
63 pts
Location
China
Sponsor
Shanghai Pharmaceuticals Holdi
NCT06928662 Phase 1, Phase 2
Recruiting
Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiatio...
Condition
Acute Myeloid Leukemia
Enrollment
36 pts
Location
United States
Sponsor
Fred Hutchinson Cancer Center
NCT06941272 Phase 1, Phase 2
Recruiting
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refr...
Condition
Malignant Neoplasm
Enrollment
50 pts
Location
United States, Australia, Belgium
Sponsor
Merck Sharp & Dohme LLC
NCT07226895 Phase 1, Phase 2
Recruiting
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT198...
Condition
Clinical High Risk for Psychosis (CHR)
Enrollment
150 pts
Location
United States
Sponsor
Monument Therapeutics Limited
NCT06385275 Phase 1, Phase 2
Recruiting
The Role of Vitamin K on Knee Osteoarthritis Outcomes
Condition
Osteo Arthritis Knee
Enrollment
55 pts
Location
United States
Sponsor
Boston University
NCT06047379 Phase 1, Phase 2
Recruiting
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblast...
Condition
Diffuse Astrocytoma, IDH-Mutant
Enrollment
134 pts
Location
United States
Sponsor
Neonc Technologies, Inc.
NCT07249905 Phase 1, Phase 2
Recruiting
Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different T...
Condition
Lymphoma
Enrollment
180 pts
Location
Australia
Sponsor
ModeX Therapeutics, An OPKO He
NCT04703842 Phase 1, Phase 2
Recruiting
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure Wit...
Condition
Congestive Heart Failure
Enrollment
57 pts
Location
United States
Sponsor
Sardocor Corp.
NCT06030622 Phase 1, Phase 2
Recruiting
Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic C...
Condition
Pancreatic Cancer Metastatic
Enrollment
25 pts
Location
United States
Sponsor
State University of New York -
NCT07235202 Phase 1, Phase 2
Recruiting
A Study of MR001 Combined With Chemotherapy in Patients With Locally Advanced or...
Condition
Pancreatic Ductal Adenocarcinoma (PDAC)
Enrollment
45 pts
Location
China
Sponsor
Shenzhen Majory Biotechnology
NCT04263831 Phase 1, Phase 2
Recruiting
Low Dose IL-2 for the Treatment of Crohn's Disease
Condition
Crohn Disease
Enrollment
30 pts
Location
United States
Sponsor
Boston Children's Hospital
NCT06519773 Phase 1, Phase 2
Recruiting
Modified Periosteal Inhibition with Simultaneous Implant Placement in Aesthetic ...
Condition
Immediate Dental Implant
Enrollment
20 pts
Location
Egypt
Sponsor
Tanta University
NCT04300556 Phase 1, Phase 2
Recruiting
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein ...
Condition
Solid Tumor
Enrollment
182 pts
Location
United States, France, Japan
Sponsor
Eisai Inc.
NCT06622486 Phase 1, Phase 2
Recruiting
First-in-human Trial of EGL-001 in Patients with Selected Advanced And/or Metast...
Condition
Solid Tumor, Adult
Enrollment
50 pts
Location
France, Spain
Sponsor
Egle Therapeutics
NCT06166056 Phase 1, Phase 2
Recruiting
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled...
Condition
Bronchiectasis
Enrollment
45 pts
Location
United Kingdom
Sponsor
Chiesi Farmaceutici S.p.A.
NCT03424850 Phase 1, Phase 2
Recruiting
Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate ...
Condition
Prostate Cancer
Enrollment
36 pts
Location
United States
Sponsor
Washington University School o
NCT06839456 Phase 1, Phase 2
Recruiting
Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infectio...
Condition
Leukemia
Enrollment
100 pts
Location
United States
Sponsor
Children's Hospital of Philade
NCT06600022 Phase 1, Phase 2
Recruiting
Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB41 in ...
Condition
Advanced Malignant Solid Tumours
Enrollment
441 pts
Location
China
Sponsor
Sinocelltech Ltd.
NCT06834529 Phase 1, Phase 2
Recruiting
CAR2219 CAR-T Cells for the Treatment of R/R B Cell Leukemia and Lymphoma
Condition
Relapsed or Refractory B Cell Leukemia and Lymphoma
Enrollment
20 pts
Location
China
Sponsor
Affiliated Hospital to Academy
NCT05608681 Phase 1, Phase 2
Recruiting
A Trial to Evaluate EP-104GI in Adults With Eosinophilic Esophagitis (EoE).
Condition
Eosinophilic Esophagitis
Enrollment
117 pts
Location
Australia, Canada, Netherlands
Sponsor
Eupraxia Pharmaceuticals Inc.
NCT06395519 Phase 1, Phase 2
Recruiting
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Condition
Advanced or Metastatic Solid Tumors
Enrollment
120 pts
Location
United States
Sponsor
858 Therapeutics, Inc.
NCT06559553 Phase 1, Phase 2
Recruiting
"Selinexor+Pegaspargase+Dexamethasone"in Ⅰ/Ⅱ NKTCL
Condition
NKTCL
Enrollment
50 pts
Location
China
Sponsor
Mingzhi Zhang