Clinical Trials / Browse by Phase / Phase 1 / Phase 2
Browse by Phase

Phase 1 / Phase 2 Clinical Trials

Phase 1/2 combined trials evaluate both safety (Phase 1) and preliminary efficacy (Phase 2) in a single study protocol, often used to accelerate early development.

Total Trials
374
Recruiting Now
374
Top Conditions in Phase 1 / Phase 2
Advanced Solid Tumor (15) Solid Tumor (10) Advanced Solid Tumors (10) Prostate Cancer (9) Breast Cancer (9) Non Small Cell Lung Cancer (8) Ovarian Cancer (7) Non-small Cell Lung Cancer (7) Endometrial Cancer (6) Colorectal Cancer (6)
NCT06834035 Phase 1, Phase 2
Recruiting
Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullos...
Condition
Epidermolysis Bullosa
Enrollment
8 pts
Location
United States
Sponsor
M. Peter Marinkovich
View Trial →
NCT07301710 Phase 1, Phase 2
Recruiting
Low-Tech Treatments for Obstructive Sleep Apnea
Condition
Obstructive Sleep Apnea (OSA)
Enrollment
60 pts
Location
United States
Sponsor
Uniformed Services University
View Trial →
NCT06138743 Phase 1, Phase 2
Recruiting
Study of ARO-DM1 in Subjects With Type 1 Myotonic Dystrophy
Condition
Myotonic Dystrophy 1
Enrollment
78 pts
Location
Australia, New Zealand, Taiwan
Sponsor
Arrowhead Pharmaceuticals
View Trial →
NCT06778850 Phase 1, Phase 2
Recruiting
A Phase I/IIa Clinical Study to Assess the Single and Multiple Ascending Doses o...
Condition
Overweight and Obese Volunteers
Enrollment
131 pts
Location
China
Sponsor
MindRank AI Ltd
View Trial →
NCT05218889 Phase 1, Phase 2
Recruiting
Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metasta...
Condition
Pancreatic Cancer
Enrollment
90 pts
Location
China
Sponsor
Chinese PLA General Hospital
View Trial →
NCT06880913 Phase 1, Phase 2
Recruiting
Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL
Condition
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Enrollment
50 pts
Location
China
Sponsor
Peking University People's Hos
View Trial →
NCT07396155 Phase 1, Phase 2
Recruiting
Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cell Therapy i...
Condition
Diabetic Nephropathy Type 2
Enrollment
10 pts
Location
Indonesia
Sponsor
PT. Prodia Stem Cell Indonesia
View Trial →
NCT05263960 Phase 1, Phase 2
Recruiting
A Study of CM350 in Patients With Advanced Solid Tumors
Condition
Advanced Solid Tumor
Enrollment
248 pts
Location
China
Sponsor
Keymed Biosciences Co.Ltd
View Trial →
NCT07220668 Phase 1, Phase 2
Recruiting
Sense4Safety Intervention
Condition
Mild Cognitive Impairment
Enrollment
200 pts
Location
United States
Sponsor
University of Pennsylvania
View Trial →
NCT05481879 Phase 1, Phase 2
Recruiting
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DY...
Condition
Myotonic Dystrophy Type 1 (DM1)
Enrollment
116 pts
Location
United States, Australia, France
Sponsor
Dyne Therapeutics
View Trial →
NCT05660980 Phase 1, Phase 2
Recruiting
Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virolog...
Condition
HIV-1-infection
Enrollment
90 pts
Location
United States, Botswana, Brazil
Sponsor
National Institute of Allergy
View Trial →
NCT05989841 Phase 1, Phase 2
Recruiting
Mitigating PTSD-CUD After Sexual Assault
Condition
Posttraumatic Stress Disorder
Enrollment
68 pts
Location
United States
Sponsor
University of Nevada, Las Vega
View Trial →
NCT05445154 Phase 1, Phase 2
Recruiting
SKLB1028, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed...
Condition
Newly Diagnosed Acute Myeloid Leukemia (AML)
Enrollment
58 pts
Location
China
Sponsor
CSPC ZhongQi Pharmaceutical Te
View Trial →
NCT06678113 Phase 1, Phase 2
Recruiting
Study to Assess the Safety and Efficacy of Intravenous BSG005 in Patients With I...
Condition
Invasive Fungal Infection
Enrollment
15 pts
Location
India
Sponsor
Biosergen AS
View Trial →
NCT07208773 Phase 1, Phase 2
Recruiting
A Study of YL201 and Ivonescimab (AK112) in Advanced Solid Tumors
Condition
Advanced Solid Tumors
Enrollment
260 pts
Location
China
Sponsor
MediLink Therapeutics (Suzhou)
View Trial →
NCT07180927 Phase 1, Phase 2
Recruiting
DLL3 CAR-T Therapy Targeting Brain Tumors
Condition
Glioblastoma of Cerebellum
Enrollment
30 pts
Location
China
Sponsor
Shenzhen Geno-Immune Medical I
View Trial →
NCT00967785 Phase 1, Phase 2
Recruiting
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
Condition
Leukopenia
Enrollment
20 pts
Location
United States
Sponsor
National Institute of Allergy
View Trial →
NCT04924491 Phase 1, Phase 2
Recruiting
Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Prevent Re...
Condition
Heart Transplantation
Enrollment
11 pts
Location
Spain
Sponsor
Rafael Correa-Rocha
View Trial →
NCT06700538 Phase 1, Phase 2
Recruiting
Study of ARO-INHBE in Adults With Obesity With and Without Diabetes Mellitus
Condition
Obesity
Enrollment
120 pts
Location
New Zealand
Sponsor
Arrowhead Pharmaceuticals
View Trial →
NCT07291076 Phase 1, Phase 2
Recruiting
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combina...
Condition
Hepatocellular Carcinoma (HCC)
Enrollment
129 pts
Location
United States, Australia, Chile
Sponsor
Bristol-Myers Squibb
View Trial →
NCT06617793 Phase 1, Phase 2
Recruiting
An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB...
Condition
Relapsing Multiple Sclerosis
Enrollment
28 pts
Location
Australia, France, Germany
Sponsor
Novartis Pharmaceuticals
View Trial →
NCT03836950 Phase 1, Phase 2
Recruiting
rTMS to Improve Cognition in Parkinson's
Condition
Parkinson's Disease
Enrollment
56 pts
Location
United States
Sponsor
VA Office of Research and Deve
View Trial →
NCT07250750 Phase 1, Phase 2
Recruiting
A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia G...
Condition
Myasthenia Gravis
Enrollment
96 pts
Location
United States, Bulgaria, Italy
Sponsor
ImmunAbs Inc.
View Trial →
NCT07340697 Phase 1, Phase 2
Recruiting
Evaluate RLS-1496 Topical Cream for Actinic Keratosis
Condition
Actinic Keratosis (AK)
Enrollment
24 pts
Location
United States
Sponsor
Rubedo Life Sciences, Inc.
View Trial →
NCT03294889 Phase 1, Phase 2
Recruiting
ONE-SHOT Trial - Ultra-hypofractionated Single-dose SBRT for Prostate Cancer
Condition
Prostate Cancer
Enrollment
45 pts
Location
Switzerland
Sponsor
University Hospital, Geneva
View Trial →
Page 11 of 15 — 374 trials total
← Prev Next →