At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
This study compares receiving cancer treatment at home versus in a clinic for patients with advanced anal cancer. The research aims to determine if at-home treatment is as effective and safe as receiving treatment in a traditional clinical setting.
Key Objective:This trial tests whether at-home cancer therapy can provide the same cancer-fighting benefits as in-clinic treatment while potentially improving convenience and quality of life for patients.
Who to Consider:Patients with advanced anal carcinoma who are interested in exploring treatment options that may allow them to receive care in the comfort of their home should consider enrolling.
Trial Parameters
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Brief Summary
This clinical trial studies the effect of cancer directed therapy given at-home versus in the clinic for patients with cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Currently most drug-related cancer care is conducted in infusion centers or specialty hospitals, where patients spend many hours a day isolated from family, friends, and familiar surroundings. This separation adds to the physical, emotional, social, and financial burden for patients and their families. The logistics and costs of navigating cancer treatments have become a principal contributor to patients' reduced quality of life. It is therefore important to reduce the burden of cancer in the lives of patients and their caregivers, and a vital aspect of this involves moving beyond traditional hospital and clinic-based care and evaluate innovative care delivery models with virtual capabilities. Providing cancer treatment at-home, versus in the clinic, may help reduce psychological and financial distress and increase treatment compliance, especially for marginalized patients and communities.
Eligibility Criteria
Inclusion Criteria: * Female or male patients with histologically confirmed malignancy. Patients with hepatocellular carcinoma (HCC) are eligible based on imaging diagnosis along; histologic confirmation is not required. * Participant must be receiving a standard-of-care treatment regimen listed in this protocol that is being used in accordance with standard medical practice. Specifically, it must be either a) FDA-approved for the participant's disease indication, or b) recommended in nationally recognized professional guidelines (e.g. NCCN, ASCO, ASH, etc.) as standard of care for the disease indication. Off-label use is permitted only if supported by such guidelines. * Note, patients diagnosed with any of the following disease types may receive any of the eligible regimens listed. Additionally, patients receiving immunotherapy, such as nivolumab or pembrolizumab, may receive these infusions in home supplemental to any of the regimens identified. Patients may receive any combination o