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advanced malignant solid neoplasm

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 2, Phase 1, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for advanced malignant solid neoplasm sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — advanced malignant solid neoplasm Clinical Trials

How many clinical trials are currently recruiting for advanced malignant solid neoplasm?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for advanced malignant solid neoplasm, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for advanced malignant solid neoplasm?
advanced malignant solid neoplasm research spans Phase 1 (3 trials), Phase 2 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a advanced malignant solid neoplasm clinical trial?
Eligibility criteria for advanced malignant solid neoplasm trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
3
Phase 2
3
Top Sponsors
National Cancer Institute (NCI) 2 trials
Northwestern University 1 trial
M.D. Anderson Cancer Center 1 trial
OHSU Knight Cancer Institute 1 trial

Recruiting Clinical Trials

NCT05733000 Phase 2
Recruiting
CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors
Enrollment
94 pts
Location
United States
Sponsor
Northwestern University
View Trial →
NCT05564377 Phase 2
Recruiting
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Enrollment
2,900 pts
Location
United States, Puert...
Sponsor
National Cancer Institute (NCI...
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NCT05691517 Phase 1
Recruiting
Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers
Enrollment
35 pts
Location
United States
Sponsor
National Cancer Institute (NCI...
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NCT04693468 Phase 1
Recruiting
Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial
Enrollment
111 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
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NCT06320405 Phase 1, Phase 2
Recruiting
Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors
Enrollment
38 pts
Location
United States
Sponsor
OHSU Knight Cancer Institute
View Trial →

Related Conditions

metastatic malignant solid neoplasm (4) recurrent malignant solid neoplasm (3) advanced biliary tract carcinoma (1) advanced colorectal carcinoma (1) advanced gastroesophageal junction adenocarcinoma (1) advanced lung adenocarcinoma (1) advanced ovarian carcinoma (1) advanced pancreatic carcinoma (1) advanced urothelial carcinoma (1) clinical stage iii gastroesophageal junction adenocarcinoma ajcc v8 (1) clinical stage iv gastroesophageal junction adenocarcinoma ajcc v8 (1) metastatic biliary tract carcinoma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology