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advanced hepatocellular carcinoma

Total Trials
4
Recruiting Now
4
Trial Phases
Phase 2, Phase 1, Phase 2, Phase 1

ClinicalMetric tracks all active clinical trials for advanced hepatocellular carcinoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — advanced hepatocellular carcinoma Clinical Trials

How many clinical trials are currently recruiting for advanced hepatocellular carcinoma?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for advanced hepatocellular carcinoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for advanced hepatocellular carcinoma?
advanced hepatocellular carcinoma research spans Phase 1 (2 trials), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a advanced hepatocellular carcinoma clinical trial?
Eligibility criteria for advanced hepatocellular carcinoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
2
Top Sponsors
Yonsei University 1 trial
Mary Feng, MD 1 trial
Devalingam Mahalingam 1 trial
M.D. Anderson Cancer Center 1 trial

Recruiting Clinical Trials

NCT06595108
Recruiting
Atezolizumab and BEvacizumab With STereotactic Body Radiotherapy for Advanced Hepatocellular Carcinoma
Enrollment
33 pts
Location
South Korea
Sponsor
Yonsei University
View Trial →
NCT04430452 Phase 2
Recruiting
Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular Carcinoma
Enrollment
21 pts
Location
United States
Sponsor
Mary Feng, MD
View Trial →
NCT07042919 Phase 1, Phase 2
Recruiting
Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer
Enrollment
59 pts
Location
United States
Sponsor
Devalingam Mahalingam
View Trial →
NCT05092373 Phase 1
Recruiting
Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax
Enrollment
43 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
View Trial →

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology