State SC
Clinical Trials in South Carolina
South Carolina is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in South Carolina and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 167 actively recruiting studies with South Carolina sites out of 167 registered in total. The busiest research areas in South Carolina are Heart Failure, Stroke, Depression. Leading sponsors running trials in the state include Medical University of South Carolina, AstraZeneca, VA Office of Research and Development. By stage, South Carolina trials break down as Phase 1 (13), Phase 2 (33), Phase 3 (55), Phase 4 (5).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in South Carolina
Frequently Asked Questions — Clinical Trials in South Carolina
How many clinical trials are currently recruiting in South Carolina?
ClinicalMetric currently tracks 167 actively recruiting clinical trials with at least one location in South Carolina. The total number of registered studies—including active but not currently enrolling trials—is 167. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in South Carolina?
South Carolina hosts clinical trials across a broad range of medical conditions, including Heart Failure, Stroke, Depression, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout South Carolina serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in South Carolina?
To join a clinical trial in South Carolina, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in South Carolina maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in South Carolina
NCT04994756 N/A
Recruiting
Stroke Thrombectomy and Aneurysm Registry
Condition
Stroke
Enrollment
40,000 pts
Location
United States, Canada, Germany
Sponsor
Medical University of South Ca
NCT06873945 Phase 3
Recruiting
A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alop...
Condition
Alopecia Areata
Enrollment
674 pts
Location
United States, Canada, China
Sponsor
Pfizer
NCT06226883 Phase 2
Recruiting
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Activ...
Condition
Inflammatory Bowel Diseases
Enrollment
385 pts
Location
United States, Australia, Austria
Sponsor
Morphic Therapeutic, Inc. (A W
NCT05019495 N/A
Recruiting
Optimizing Tobacco Treatment Delivery for People Living With HIV
Condition
Hiv
Enrollment
231 pts
Location
United States
Sponsor
Medical University of South Ca
NCT07908381 Phase 2, Phase 3
Recruiting
A Study to Investigate the Efficacy and Safety of Zelicapavir Compared With Plac...
Condition
RSV
Enrollment
860 pts
Location
United States
Sponsor
Enanta Pharmaceuticals, Inc
NCT07202039 N/A
Recruiting
Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use ...
Condition
Tobacco-flavored EC
Enrollment
90 pts
Location
United States
Sponsor
Prisma Health-Upstate
NCT05553353 N/A
Recruiting
Dosing rTMS for Depression Post-SCI
Condition
Spinal Cord Injuries
Enrollment
24 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT07553637 Phase 2
Recruiting
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Condition
Treatment-resistant Depression (TRD)
Enrollment
178 pts
Location
United States, United Kingdom
Sponsor
Alto Neuroscience
NCT06585774 Phase 3
Recruiting
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chro...
Condition
Chronic Graft-versus-host-disease
Enrollment
240 pts
Location
United States, Australia, Austria
Sponsor
Incyte Corporation
NCT07113522 Phase 2
Recruiting
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
Condition
Inflammatory Bowel Disease (IBD)
Enrollment
140 pts
Location
United States, Canada, Georgia
Sponsor
Mirador Therapeutics, Inc.
NCT04333537 Phase 2, Phase 3
Recruiting
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Pat...
Condition
Buccal Mucosa Squamous Cell Carcinoma
Enrollment
686 pts
Location
United States, Canada
Sponsor
NRG Oncology
NCT07538622 N/A
Recruiting
Prospective Post Market Clinical Registry for the Zenflow Spring System - A Mini...
Condition
BPH (Benign Prostatic Hyperplasia)
Enrollment
300 pts
Location
United States
Sponsor
Zenflow, Inc.
NCT06937086 Phase 3
Recruiting
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants W...
Condition
Ulcerative Colitis
Enrollment
350 pts
Location
United States, Austria, Belgium
Sponsor
Eli Lilly and Company
NCT06128629 Phase 3
Recruiting
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amylo...
Condition
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Enrollment
1,200 pts
Location
United States, Argentina, Australia
Sponsor
Intellia Therapeutics
NCT04588922 Phase 1, Phase 2
Recruiting
Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Pa...
Condition
Hematologic Malignancies
Enrollment
160 pts
Location
United States, China
Sponsor
Sellas Life Sciences Group
NCT06423430 N/A
Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Condition
Treatment Resistant Depression
Enrollment
100 pts
Location
United States
Sponsor
Abbott Medical Devices
NCT06064877 Phase 3
Recruiting
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recur...
Condition
Metastatic Head-and-neck Squamous-cell Carcinoma
Enrollment
410 pts
Location
United States, Australia, Belgium
Sponsor
AVEO Pharmaceuticals, Inc.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology