State RI
Clinical Trials in Rhode Island
Rhode Island is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Rhode Island and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 65 actively recruiting studies with Rhode Island sites out of 65 registered in total. The busiest research areas in Rhode Island are Ulcerative Colitis, Malignant Solid Neoplasm, Advanced Solid Tumor. Leading sponsors running trials in the state include Rhode Island Hospital, National Cancer Institute (NCI), SWOG Cancer Research Network. By stage, Rhode Island trials break down as Phase 1 (11), Phase 2 (13), Phase 3 (25), Phase 4 (3).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Rhode Island
Ulcerative Colitis (2)Malignant Solid Neoplasm (2)Advanced Solid Tumor (2)Sickle Cell Disease (2)Acute Myeloid Leukemia (2)Endometrial Cancer (2)Anatomic Stage IV Breast Cancer AJCC v8 (1)Estrogen Receptor Positive (1)HER2/Neu Negative (1)Progesterone Receptor Positive (1)Prognostic Stage IV Breast Cancer AJCC v8 (1)Elevated CA15-3 or CEA or CA27-29 (1)
Frequently Asked Questions — Clinical Trials in Rhode Island
How many clinical trials are currently recruiting in Rhode Island?
ClinicalMetric currently tracks 65 actively recruiting clinical trials with at least one location in Rhode Island. The total number of registered studies—including active but not currently enrolling trials—is 65. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Rhode Island?
Rhode Island hosts clinical trials across a broad range of medical conditions, including Ulcerative Colitis, Malignant Solid Neoplasm, Advanced Solid Tumor, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Rhode Island serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Rhode Island?
To join a clinical trial in Rhode Island, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Rhode Island maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Rhode Island
NCT03723928 N/A
Recruiting
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Re...
Condition
Anatomic Stage IV Breast Cancer AJCC v8
Enrollment
739 pts
Location
United States, Guam, Puerto Rico
Sponsor
SWOG Cancer Research Network
NCT04166409 Phase 3
Recruiting
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients Wit...
Condition
Low Grade Astrocytoma
Enrollment
170 pts
Location
United States, Canada, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT07165028 Phase 3
Recruiting
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associ...
Condition
Metabolic Dysfunction-Associated Steatotic Liver Disease
Enrollment
4,500 pts
Location
United States, Argentina, Australia
Sponsor
Eli Lilly and Company
NCT00009633 N/A
Recruiting
Follow-up Visit of High Risk Infants
Condition
Infant, Newborn
Enrollment
68,000 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT06667141 Phase 1
Recruiting
Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors
Condition
Specific Advanced Solid Tumors
Enrollment
100 pts
Location
United States
Sponsor
Acrivon Therapeutics
NCT06152575 Phase 3
Recruiting
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in P...
Condition
Multiple Myeloma
Enrollment
492 pts
Location
United States, Argentina, Australia
Sponsor
Pfizer
NCT06095128 Phase 4
Recruiting
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Condition
Ulcerative Colitis
Enrollment
65 pts
Location
United States, Canada
Sponsor
Takeda
NCT06699212 Phase 3
Recruiting
A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in Firs...
Condition
Recurrent Head and Neck Squamous Cell Carcinoma
Enrollment
412 pts
Location
United States, Japan, Taiwan
Sponsor
Rakuten Medical, Inc.
NCT06272045 N/A
Recruiting
Early Intervention to Promote Cardiovascular Health of Mothers and Children
Condition
Cardiovascular Health
Enrollment
6,618 pts
Location
United States
Sponsor
JHSPH Center for Clinical Tria
NCT07545772 Phase 2
Recruiting
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome...
Condition
Irritable Bowel Syndrome
Enrollment
342 pts
Location
United States, Belgium, Canada
Sponsor
Eli Lilly and Company
NCT05630794 Phase 1
Recruiting
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
Condition
Colorectal Adenomatous Polyp
Enrollment
36 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT07684235 Phase 3
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of ...
Condition
Obesity
Enrollment
3,200 pts
Location
United States, Australia, Japan
Sponsor
Amgen
NCT07529717 Phase 1, Phase 2
Recruiting
First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostat...
Condition
Metastatic Prostate Cancer
Enrollment
42 pts
Location
United States, Australia, South Korea
Sponsor
AstraZeneca
NCT05317858 Phase 3
Recruiting
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standar...
Condition
Brain Tumor
Enrollment
30 pts
Location
United States, Canada, South Korea
Sponsor
InSightec
NCT07196748 Phase 3
Recruiting
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Mode...
Condition
Colitis, Ulcerative
Enrollment
882 pts
Location
United States, Argentina, Australia
Sponsor
Janssen Research & Development
NCT06942455 N/A
Recruiting
A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle Sch...
Condition
Sleep
Enrollment
300 pts
Location
United States, Puerto Rico
Sponsor
Rhode Island Hospital
NCT06822426 Phase 3
Recruiting
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodst...
Condition
Central Line Associated Blood Stream Infections (CLABSI)
Enrollment
200 pts
Location
United States, Turkey (Türkiye)
Sponsor
CorMedix Therapeutics
NCT07219953 Phase 3
Recruiting
A Study of Brenipatide in Participants With Alcohol Use Disorder
Condition
Alcohol Use Disorder
Enrollment
1,100 pts
Location
United States, Belgium, China
Sponsor
Eli Lilly and Company
NCT06581328 Phase 4
Recruiting
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in t...
Condition
Ulcerative Colitis
Enrollment
400 pts
Location
United States
Sponsor
Takeda
NCT05999032 N/A
Recruiting
The Puerto Rico Asthma Integrated Response Program ("PR-AIR")
Condition
Pediatric Asthma
Enrollment
480 pts
Location
United States, Puerto Rico
Sponsor
Rhode Island Hospital
NCT06543407 N/A
Recruiting
Harm Reduction for Smokers With Mental Illness
Condition
Tobacco Dependence
Enrollment
250 pts
Location
United States
Sponsor
Dartmouth-Hitchcock Medical Ce
NCT04871542 N/A
Recruiting
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
Condition
Malignant Solid Neoplasm
Enrollment
2,062 pts
Location
United States, Chile, Guam
Sponsor
SWOG Cancer Research Network
NCT07144631 N/A
Recruiting
Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome
Condition
Restless Leg Disorder
Enrollment
15 pts
Location
United States
Sponsor
Rhode Island Hospital
NCT05702021 N/A
Recruiting
Implementing Contingency Management for Stimulant Use in Specialty Addiction Tre...
Condition
Stimulant Use (Diagnosis)
Enrollment
76 pts
Location
United States
Sponsor
Northwestern University
NCT02523014 Phase 2
Recruiting
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating ...
Condition
Intracranial Meningioma
Enrollment
124 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
Page 1 of 3 — 65 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology