State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 481 actively recruiting studies with Pennsylvania sites out of 481 registered in total. The busiest research areas in Pennsylvania are Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, National Cancer Institute (NCI). By stage, Pennsylvania trials break down as Phase 1 (77), Phase 2 (124), Phase 3 (115), Phase 4 (15).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 481 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 481. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Breast Cancer, Acute Myeloid Leukemia, Ovarian Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT06423430 N/A
Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Condition
Treatment Resistant Depression
Enrollment
100 pts
Location
United States
Sponsor
Abbott Medical Devices
NCT05541029 N/A
Recruiting
Music Listening: A Mechanistic Trial
Condition
Critical Illness
Enrollment
171 pts
Location
United States
Sponsor
University of Pittsburgh
NCT05380531 N/A
Recruiting
Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section
Condition
Cesarean Section Complications
Enrollment
700 pts
Location
United States
Sponsor
Senthil Sadhasivam
NCT07801495 Phase 2
Recruiting
A Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participant...
Condition
Moderate to Severe Psoriatic Arthritis
Enrollment
220 pts
Location
United States
Sponsor
Novartis Pharmaceuticals
NCT07787039 N/A
Recruiting
Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase
Condition
Opioid Use Disorder
Enrollment
10 pts
Location
United States
Sponsor
Friends Research Institute, In
NCT05654922 Phase 3
Recruiting
Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progress...
Condition
Pre-Bronchiolitis Obliterans Syndrome
Enrollment
100 pts
Location
United States
Sponsor
Renovion, Inc.
NCT07406633 Phase 2
Recruiting
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIS...
Condition
GIST - Gastrointestinal Stromal Tumor
Enrollment
46 pts
Location
United States
Sponsor
Kumquat Biosciences Inc.
NCT07003425 Phase 2
Recruiting
A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis
Condition
Atopic Dermatitis
Enrollment
350 pts
Location
United States, Canada, Czechia
Sponsor
Apogee Therapeutics, Inc.
NCT06286397 Phase 2
Recruiting
Topical Anti-Androgens in Pilonidal Sinus Disease
Condition
Pilonidal Disease
Enrollment
75 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06652347 N/A
Recruiting
Understanding the Preferences and Views of Older Adults on the Use of Geriatric ...
Condition
Care Delivery
Enrollment
100 pts
Location
United States
Sponsor
Fox Chase Cancer Center
NCT02493478 N/A
Recruiting
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Condition
Failed or Difficult Intubation, Sequela
Enrollment
150,000 pts
Location
United States, Australia, Austria
Sponsor
Children's Hospital of Philade
NCT06964685 N/A
Recruiting
Assessment of Support With Impella® Best Practices in Acute Myocardial Infarctio...
Condition
AMI Cardiogenic Shock
Enrollment
350 pts
Location
United States
Sponsor
Abiomed Inc.
NCT04959097 N/A
Recruiting
Retinoblastoma Patient Clinical Database and Tissue Repository
Condition
Retinoblastoma
Enrollment
800 pts
Location
United States, Canada
Sponsor
Children's Hospital Los Angele
NCT07082738 Phase 2
Recruiting
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Ve...
Condition
Chronic Obstructive Pulmonary Disease (COPD)
Enrollment
987 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT06177717 N/A
Recruiting
Deep Functional Phenotyping of the ALA Lung Health Cohort
Condition
Lung Diseases
Enrollment
1,000 pts
Location
United States
Sponsor
Johns Hopkins University
NCT07190248 Phase 3
Recruiting
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants W...
Condition
Non-small Cell Lung Cancer
Enrollment
675 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT05065216 Phase 2, Phase 3
Recruiting
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
Condition
Acute Stroke
Enrollment
728 pts
Location
United States, Belgium, Canada
Sponsor
DiaMedica Therapeutics Inc
NCT06857435 N/A
Recruiting
Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar
Condition
Burns
Enrollment
40 pts
Location
United States
Sponsor
University of Pittsburgh
NCT06930625 Phase 3
Recruiting
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acr...
Condition
Acromegaly
Enrollment
119 pts
Location
United States, Austria, Belgium
Sponsor
Debiopharm International SA
NCT07213804 Phase 3
Recruiting
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum...
Condition
Ovarian Neoplasms
Enrollment
1,630 pts
Location
United States, Australia, Austria
Sponsor
Eli Lilly and Company
NCT07869147 Phase 2
Recruiting
Study of ORJ-001 for the Treatment of IPF
Condition
Idiopathic Pulmonary Fibrosis
Enrollment
95 pts
Location
United States
Sponsor
Oorja Bio, Inc.
NCT07577843 Phase 3
Recruiting
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn...
Condition
Crohn Disease
Enrollment
460 pts
Location
United States, Argentina, Australia
Sponsor
Janssen Research & Development
NCT04181138 N/A
Recruiting
Primary Sclerosing Cholangitis in Children
Condition
Primary Sclerosing Cholangitis
Enrollment
1,000 pts
Location
United States, Canada
Sponsor
Arbor Research Collaborative f
NCT06992258 Phase 2
Recruiting
A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintin...
Condition
Colorectal Cancer
Enrollment
120 pts
Location
United States
Sponsor
Criterium, Inc.
NCT03231150 N/A
Recruiting
Plantar Fasciitis Randomized Clinical Control Trial
Condition
Plantar Fascitis
Enrollment
62 pts
Location
United States
Sponsor
University of Pennsylvania
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology