State PA
Clinical Trials in Pennsylvania
Pennsylvania is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Pennsylvania and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 478 actively recruiting studies with Pennsylvania sites out of 478 registered in total. The busiest research areas in Pennsylvania are Prostate Cancer, Ovarian Cancer, Breast Cancer. Leading sponsors running trials in the state include University of Pennsylvania, University of Pittsburgh, Abramson Cancer Center at Penn Medicine. By stage, Pennsylvania trials break down as Phase 1 (82), Phase 2 (138), Phase 3 (101), Phase 4 (17).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Pennsylvania
Frequently Asked Questions — Clinical Trials in Pennsylvania
How many clinical trials are currently recruiting in Pennsylvania?
ClinicalMetric currently tracks 478 actively recruiting clinical trials with at least one location in Pennsylvania. The total number of registered studies—including active but not currently enrolling trials—is 478. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Pennsylvania?
Pennsylvania hosts clinical trials across a broad range of medical conditions, including Prostate Cancer, Ovarian Cancer, Breast Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Pennsylvania serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Pennsylvania?
To join a clinical trial in Pennsylvania, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Pennsylvania maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Pennsylvania
NCT05932680 Phase 2
Recruiting
Limited-duration Teclistamab
Condition
Myeloma Multiple
Enrollment
75 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT07221357 Phase 2, Phase 3
Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Che...
Condition
Untreated, Unresectable, or Metastatic Colorectal Cancer
Enrollment
990 pts
Location
United States, Argentina, Australia
Sponsor
Bristol-Myers Squibb
NCT04640584 N/A
Recruiting
C-Brace Prospective Registry
Condition
Pareses
Enrollment
250 pts
Location
United States, Australia, Germany
Sponsor
Otto Bock Healthcare Products
NCT04065399 Phase 1, Phase 2
Recruiting
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rea...
Condition
Acute Myeloid Leukemia
Enrollment
447 pts
Location
United States, Australia, Canada
Sponsor
Syndax Pharmaceuticals
NCT05552222 Phase 3
Recruiting
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR)...
Condition
Multiple Myeloma
Enrollment
1,590 pts
Location
United States, Australia, Austria
Sponsor
Janssen Research & Development
NCT06458439 Phase 2
Recruiting
Epcoritamab-CAR T Cells for Large B-cell Lymphomas
Condition
Lymphoma, Non-Hodgkin
Enrollment
31 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT06013865 Phase 4
Recruiting
Empagliflozin Treatment in Kidney Transplant Recipients
Condition
Kidney Transplant
Enrollment
264 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT06372899 N/A
Recruiting
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for P...
Condition
E-cigarette Use
Enrollment
200 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT06831149 Phase 2
Recruiting
Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstructi...
Condition
Squamous Cell Carcinoma
Enrollment
225 pts
Location
United States
Sponsor
Matthew Spector
NCT05915377 N/A
Recruiting
Researching Efficient Approaches to Delirium Identification-Sustaining Effective...
Condition
Delirium
Enrollment
1,050 pts
Location
United States
Sponsor
Penn State University
NCT06517901 N/A
Recruiting
Fusion or Cognitive Ultrasound-guided Biopsy to Detect Prostate Cancer
Condition
Prostate Cancer
Enrollment
1,306 pts
Location
United States, Canada
Sponsor
Albany Medical College
NCT06670001 N/A
Recruiting
MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure ...
Condition
HFpEF - Heart Failure With Preserved Ejection Fraction
Enrollment
270 pts
Location
United States
Sponsor
University of Pennsylvania
NCT06569693 N/A
Recruiting
Dyadic Sleep Study
Condition
Gastrointestinal Cancer
Enrollment
152 pts
Location
United States
Sponsor
University of Miami
NCT06904911 Phase 2
Recruiting
Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mech...
Condition
Acute Ischemic Stroke From Large Vessel Occlusion
Enrollment
20 pts
Location
United States
Sponsor
University of Pennsylvania
NCT04885244 N/A
Recruiting
Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Mini...
Condition
Adult Spinal Deformity
Enrollment
500 pts
Location
United States
Sponsor
International Spine Study Grou
NCT05919264 Phase 1, Phase 2
Recruiting
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Condition
Cancer
Enrollment
619 pts
Location
United States, Australia
Sponsor
Parabilis Medicines, Inc.
NCT07218016 N/A
Recruiting
Accelerometer Measured Early Recovery After Prolapse Surgery
Condition
Pelvic Organ Prolapse
Enrollment
288 pts
Location
United States
Sponsor
NICHD Pelvic Floor Disorders N
NCT02478892 N/A
Recruiting
Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inher...
Condition
Pancreatic Cancer
Enrollment
200 pts
Location
United States
Sponsor
Abramson Cancer Center at Penn
NCT02744677 N/A
Recruiting
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients...
Condition
Complex Congenital Heart Defect
Enrollment
108 pts
Location
United States
Sponsor
Edwards Lifesciences
NCT06760572 N/A
Recruiting
Airway Data Collection With the Entarik Feeding Tube System
Condition
Healthy
Enrollment
30 pts
Location
United States
Sponsor
Theranova, L.L.C.
NCT06904339 N/A
Recruiting
Communication About Sexual Health in Gynecologic Cancer
Condition
Gynecologic Cancers
Enrollment
200 pts
Location
United States
Sponsor
Fox Chase Cancer Center
NCT04047628 Phase 3
Recruiting
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for ...
Condition
Relapsing Multiple Sclerosis
Enrollment
156 pts
Location
United States
Sponsor
National Institute of Allergy
NCT06307665 Phase 3
Recruiting
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As ...
Condition
Asthma
Enrollment
440 pts
Location
United States, China, Mexico
Sponsor
AstraZeneca
NCT03767595 N/A
Recruiting
ProACT Post-Approval Study
Condition
Stress Urinary Incontinence
Enrollment
145 pts
Location
United States
Sponsor
Uromedica
NCT07580495 N/A
Recruiting
Effect of Collagen Membrane on Ridge Preservation
Condition
Dehiscence
Enrollment
30 pts
Location
United States
Sponsor
Debora Dias
Page 1 of 20 — 478 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology