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Clinical Trials in Ohio

Ohio is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Ohio and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 475 actively recruiting studies with Ohio sites out of 475 registered in total. The busiest research areas in Ohio are Ovarian Cancer, Solid Tumor, Advanced Solid Tumor. Leading sponsors running trials in the state include Children's Hospital Medical Center, Cincinnati, The Cleveland Clinic, National Cancer Institute (NCI). By stage, Ohio trials break down as Phase 1 (96), Phase 2 (140), Phase 3 (106), Phase 4 (16).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
475
Recruiting Now
475
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Top Conditions in Ohio
Ovarian Cancer (9)Solid Tumor (8)Advanced Solid Tumor (8)Heart Failure (7)Colorectal Cancer (7)Prostate Cancer (7)Schizophrenia (7)Acute Myeloid Leukemia (6)Advanced Solid Tumors (6)Chronic Lymphocytic Leukemia (6)Multiple Myeloma (5)Metastatic Castration-resistant Prostate Cancer (5)

Frequently Asked Questions — Clinical Trials in Ohio

How many clinical trials are currently recruiting in Ohio?
ClinicalMetric currently tracks 475 actively recruiting clinical trials with at least one location in Ohio. The total number of registered studies—including active but not currently enrolling trials—is 475. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Ohio?
Ohio hosts clinical trials across a broad range of medical conditions, including Ovarian Cancer, Solid Tumor, Advanced Solid Tumor, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Ohio serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Ohio?
To join a clinical trial in Ohio, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Ohio maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Ohio

NCT07573176 Phase 3
Recruiting
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Ma...
Condition
Depressive Disorder, Major
Enrollment
600 pts
Location
United States, Argentina, Brazil
Sponsor
Janssen Research & Development
View Trial →
NCT04920617 Phase 2
Recruiting
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosp...
Condition
Relapsed Diffuse Large B-cell Lymphoma
Enrollment
102 pts
Location
United States, Australia, Canada
Sponsor
ImmunoVaccine Technologies, In
View Trial →
NCT07499258 N/A
Recruiting
Axonics R20 Post-Market Clinical Follow-up (PMCF) Study for the Indication of Fe...
Condition
Fecal Incontinence
Enrollment
55 pts
Location
United States, United Kingdom
Sponsor
Axonics, Inc.
View Trial →
NCT06718491 N/A
Recruiting
Brief Digitally-Enhanced Intervention for Reducing Alcohol Use During MOUD
Condition
Opioid Use Disorder
Enrollment
80 pts
Location
United States
Sponsor
Ohio State University
View Trial →
NCT06424522 N/A
Recruiting
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low An...
Condition
Low Anterior Resection Syndrome
Enrollment
80 pts
Location
United States
Sponsor
Ohio State University Comprehe
View Trial →
NCT06293703 N/A
Recruiting
Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study...
Condition
Morbid Obesity
Enrollment
262 pts
Location
United States
Sponsor
Salvador Navarrete
View Trial →
NCT06636383 N/A
Recruiting
Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program
Condition
Glycogen Storage Disease Type Ia
Enrollment
140 pts
Location
United States, Brazil, Canada
Sponsor
Ultragenyx Pharmaceutical Inc
View Trial →
NCT07759154 Phase 3
Recruiting
A Study to Test the Effects of Centanafadine in Adults With Attention-deficit/Hy...
Condition
Attention-deficit/Hyperactivity Disorder
Enrollment
80 pts
Location
United States
Sponsor
Otsuka Pharmaceutical Developm
View Trial →
NCT07793942 Phase 2
Recruiting
A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With...
Condition
Malignant Neoplam
Enrollment
480 pts
Location
United States, Canada, Switzerland
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT07026786 N/A
Recruiting
Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Reco...
Condition
Pain After Surgery
Enrollment
50 pts
Location
United States
Sponsor
University Hospitals Cleveland
View Trial →
NCT07216027 Phase 2
Recruiting
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
Condition
Atopic Dermatitis
Enrollment
165 pts
Location
United States, Bulgaria, Canada
Sponsor
Pfizer
View Trial →
NCT07756541 N/A
Recruiting
POP SINGER Randomized Clinical Trial
Condition
Chronic Pain
Enrollment
130 pts
Location
United States
Sponsor
University Hospitals Cleveland
View Trial →
NCT07817251 Phase 3
Recruiting
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semagl...
Condition
Diabetes Mellitus, Type 2
Enrollment
210 pts
Location
United States
Sponsor
Novo Nordisk A/S
View Trial →
NCT05955261 Phase 2
Recruiting
A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric...
Condition
Acute Myeloid Leukemia
Enrollment
70 pts
Location
United States
Sponsor
St. Jude Children's Research H
View Trial →
NCT07369154 Phase 3
Recruiting
52-week Open Label Safety-Tolerability Study
Condition
Schizophrenia
Enrollment
900 pts
Location
United States
Sponsor
LB Pharmaceuticals Inc.
View Trial →
NCT06351605 N/A
Recruiting
A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degener...
Condition
Dry Age-related Macular Degeneration
Enrollment
500 pts
Location
United States, Norway
Sponsor
LumiThera, Inc.
View Trial →
NCT07265674 Phase 3
Recruiting
A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (P...
Condition
Advanced Biliary Tract Cancer
Enrollment
480 pts
Location
United States
Sponsor
J-Pharma Co., Ltd.
View Trial →
NCT06767514 Phase 3
Recruiting
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patie...
Condition
Non-Small Cell Lung Cancer
Enrollment
780 pts
Location
United States, Belgium, Canada
Sponsor
Summit Therapeutics
View Trial →
NCT07397338 Phase 1, Phase 2
Recruiting
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Sol...
Condition
Advanced Solid Tumors
Enrollment
370 pts
Location
United States
Sponsor
Revolution Medicines, Inc.
View Trial →
NCT07116967 Phase 3
Recruiting
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants Wit...
Condition
Plaque Psoriasis
Enrollment
3,040 pts
Location
United States, Argentina, Australia
Sponsor
Bristol-Myers Squibb
View Trial →
NCT06594393 Phase 2
Recruiting
A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study
Condition
Epidermolysis Bullosa (EB)
Enrollment
32 pts
Location
United States, France, Greece
Sponsor
Xinnate AB
View Trial →
NCT07764614 N/A
Recruiting
Tornier Perform™ Reversed Monopost Study
Condition
Non-inflammatory Degenerative Joint Disease
Enrollment
150 pts
Location
United States
Sponsor
Stryker Trauma and Extremities
View Trial →
NCT06543381 Phase 1
Recruiting
Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML Af...
Condition
Acute Myeloid Leukemia
Enrollment
15 pts
Location
United States
Sponsor
City of Hope Medical Center
View Trial →
NCT06740630 Phase 3
Recruiting
A Study on the Immune Response and Safety of an Investigational Chickenpox Vacci...
Condition
Chickenpox
Enrollment
1,840 pts
Location
United States, Belgium, Colombia
Sponsor
GlaxoSmithKline
View Trial →
NCT07421700 Phase 1, Phase 2
Recruiting
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With...
Condition
Urothelial Cancer
Enrollment
132 pts
Location
United States, Australia, China
Sponsor
Pfizer
View Trial →
Page 4 of 19 — 475 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology