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Clinical Trials in Maryland

Maryland is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Maryland and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 402 actively recruiting studies with Maryland sites out of 402 registered in total. The busiest research areas in Maryland are Stroke, Obesity, Prostate Cancer. Leading sponsors running trials in the state include Johns Hopkins University, National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID). By stage, Maryland trials break down as Phase 1 (64), Phase 2 (92), Phase 3 (83), Phase 4 (5).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
402
Recruiting Now
402
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Top Conditions in Maryland
Stroke (8)Obesity (5)Prostate Cancer (5)Schizophrenia (5)Acute Myeloid Leukemia (5)Healthy Volunteers (5)Cervical Cancer (4)Heart Failure (4)Carcinoma, Non-Small-Cell Lung (4)Malignant Solid Neoplasm (3)Retinitis Pigmentosa (3)B Acute Lymphoblastic Leukemia (3)

Frequently Asked Questions — Clinical Trials in Maryland

How many clinical trials are currently recruiting in Maryland?
ClinicalMetric currently tracks 402 actively recruiting clinical trials with at least one location in Maryland. The total number of registered studies—including active but not currently enrolling trials—is 402. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Maryland?
Maryland hosts clinical trials across a broad range of medical conditions, including Stroke, Obesity, Prostate Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Maryland serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Maryland?
To join a clinical trial in Maryland, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Maryland maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Maryland

NCT06145477 N/A
Recruiting
Parenting for Tomorrow: A New Model for Supporting Preschool Children's Mental H...
Condition
Parenting
Enrollment
160 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT06082453 N/A
Recruiting
Modernizing Perinatal Syphilis Testing
Condition
Syphilis
Enrollment
924 pts
Location
United States
Sponsor
The University of Texas Health
View Trial →
NCT06771583 N/A
Recruiting
Identification and Validation of Epigenetic Biomarkers of PMDD
Condition
PMDD
Enrollment
500 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT06405594 N/A
Recruiting
Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia
Condition
Aphasia, Acquired
Enrollment
350 pts
Location
United States
Sponsor
University of Maryland, Colleg
View Trial →
NCT07412756 Phase 3
Recruiting
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Condition
Depressive Disorder, Major
Enrollment
1,000 pts
Location
United States, Australia, Brazil
Sponsor
Eli Lilly and Company
View Trial →
NCT01276470 N/A
Recruiting
Environmental Risk Factors for the Anti-synthetase Syndrome
Condition
Myositis
Enrollment
580 pts
Location
United States
Sponsor
National Institute of Environm
View Trial →
NCT05588141 Phase 1, Phase 2
Recruiting
A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitra...
Condition
Brain Tumor
Enrollment
96 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT03775577 N/A
Recruiting
Exercise Intolerance in Heart Failure
Condition
Heart Failure With Normal Ejection Fraction
Enrollment
130 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT07326566 Phase 2
Recruiting
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM...
Condition
Glioblastoma (GBM)
Enrollment
162 pts
Location
United States
Sponsor
Black Diamond Therapeutics, In
View Trial →
NCT07012395 Phase 2
Recruiting
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Seve...
Condition
Ulcerative Colitis
Enrollment
645 pts
Location
United States, Argentina, Australia
Sponsor
Spyre Therapeutics, Inc.
View Trial →
NCT06638502 Phase 1, Phase 2
Recruiting
Safety of HRX215 in Patients After Minor and Major Liver Resection
Condition
Liver Resection
Enrollment
80 pts
Location
United States, France, Germany
Sponsor
HepaRegeniX GmbH
View Trial →
NCT05758701 Phase 4
Recruiting
CT TAVR Abdomen Study
Condition
Transcatheter Aortic Valve Replacement
Enrollment
164 pts
Location
United States
Sponsor
University of Maryland, Baltim
View Trial →
NCT05739981 Phase 1, Phase 2
Recruiting
Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnose...
Condition
Ovarian Cancer
Enrollment
30 pts
Location
United States
Sponsor
Imunon
View Trial →
NCT05213572 N/A
Recruiting
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease Afte...
Condition
Mortality in Sickle Cell
Enrollment
200 pts
Location
United States
Sponsor
National Heart, Lung, and Bloo
View Trial →
NCT06310031 N/A
Recruiting
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart ...
Condition
Cardiovascular Diseases
Enrollment
780 pts
Location
United States
Sponsor
BrioHealth Solutions, Inc.
View Trial →
NCT06941857 Phase 2
Recruiting
NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in...
Condition
Pancreatic Cancer
Enrollment
20 pts
Location
United States
Sponsor
Sidney Kimmel Comprehensive Ca
View Trial →
NCT07116967 Phase 3
Recruiting
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants Wit...
Condition
Plaque Psoriasis
Enrollment
3,040 pts
Location
United States, Argentina, Australia
Sponsor
Bristol-Myers Squibb
View Trial →
NCT06247267 N/A
Recruiting
The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgende...
Condition
Hypogonadism
Enrollment
75 pts
Location
United States
Sponsor
Walter Reed National Military
View Trial →
NCT06246357 Phase 2
Recruiting
Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor ...
Condition
Hyperaldosteronism
Enrollment
80 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT06788912 Phase 2
Recruiting
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell...
Condition
Lung Neoplasm Malignant
Enrollment
60 pts
Location
United States, Chile, Greece
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT06975865 Phase 3
Recruiting
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years Wit...
Condition
Sickle Cell Disease
Enrollment
192 pts
Location
United States, Belgium, Brazil
Sponsor
Sanofi
View Trial →
NCT03606967 Phase 2
Recruiting
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab...
Condition
Anatomic Stage IV Breast Cancer AJCC v8
Enrollment
86 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT00804154 Phase 1
Recruiting
Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer
Condition
Intractable Pain
Enrollment
45 pts
Location
United States
Sponsor
National Institute of Dental a
View Trial →
NCT06904066 Phase 1
Recruiting
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Partic...
Condition
Malignancy, Hematologic
Enrollment
86 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT07032545 N/A
Recruiting
Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
Condition
Obesity and Overweight
Enrollment
24 pts
Location
United States
Sponsor
University of Maryland, Baltim
View Trial →
Page 9 of 17 — 402 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology