NCT06338774 Cognitive Control to Boost Physical Activity Adherence
| NCT ID | NCT06338774 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Iowa |
| Condition | Physical Inactivity |
| Study Type | INTERVENTIONAL |
| Enrollment | 264 participants |
| Start Date | 2024-09-01 |
| Primary Completion | 2027-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 264 participants in total. It began in 2024-09-01 with a primary completion date of 2027-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle. The main questions it aims to answer are: * Can cognitive training designed to improve cognitive control improve physical activity adherence? * What are the psychological, physiological, cognitive, and sociodemographic factors that affect the impact of cognitive control on physical activity adherence? Participants will * Complete a 6-week home-based, computerized cognitive training program * Complete a 6-week home-based, aerobic exercise training program with supervision of a health coach and trainer * Complete a 6-week home-based, aerobic exercise training program prescribed by a health coach and trainer * Visit the laboratory before and after cognitive training, and before and after physical training, to complete assessments of cognition and aerobic fitness
Eligibility Criteria
Inclusion Criteria: * Between the ages of 40 and 65 years old * Full-time working status of an average of 35 hrs./week or more * Scoring as "Low Active" by the short form of the International Physical Activity Questionnaire (IPAQ) * Eligible to participate in an aerobic exercise intervention based on the Physical Activity Readiness Questionnaire * Approval from their Primary Care Physician for approval to participate in the prescribed training program * Corrected vision of 20/40 * Fluent in English to ensure instructions for cognitive assessments and training are understood clearly Exclusion Criteria: * Impairments in hearing inhibiting the ability to discuss study instructions or directions * Visual impairments that prevent the perception of color, or loss of sight in the visual field * Qualify as "high risk" for exercise-induced adverse events by American College of Sports Medicine criteria will be excluded, which includes known or symptomatic chronic cardiovascular or metabolic disease * Not fluent in English * Inability to comply with experimental instructions or access a tablet or computer to complete computerized training * Previous diagnosis of a neurological or psychiatric condition, including diagnosis with any of the following: major depression, Attention Deficit Disorder or attention-deficit/hyperactivity disorder (ADHD), schizophrenia or bipolar disorder, multiple sclerosis, epilepsy, meningitis, Parkinson's disease, stroke, Transient Ischemic Attack (TIA), or brain aneurysm surgery. * Previous diagnosis of a heart condition, cardiovascular disease, or a recent cardiovascular event (such as high blood pressure or cholesterol) that would increase the risk for an adverse event in response to vigorous exercise, Chronic obstructive pulmonary disease (COPD), uncontrolled asthma (this includes anyone who has asthma but is not on medication. * Previous diagnosis of a chronic condition such as cystic fibrosis, unregulated thyroid disorder (this includes anyone with thyroid disease that is not on medication), untreated diabetes, renal or liver disease, heart murmur, arrhythmia, or irregular heartbeat. * Previous brain surgery or injury associated with concussion or loss of consciousness that required rehabilitation or caregiver assistance to regain function (i.e., dressing/personal hygiene) * Previous diagnosis of Alzheimer\'s or related dementias * Current or previous cancer treatments within the last 6 months * Pregnant or trying to get pregnant
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06338774 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 65 Years, studying Physical Inactivity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06338774 currently recruiting?
Yes, NCT06338774 is actively recruiting participants. Contact the research team at michelle-voss@uiowa.edu for enrollment information.
Where is the NCT06338774 trial being conducted?
This trial is being conducted at Iowa City, United States, Boston, United States.
Who is sponsoring the NCT06338774 clinical trial?
NCT06338774 is sponsored by University of Iowa. The trial plans to enroll 264 participants.