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Clinical Trials in Connecticut

Connecticut is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Connecticut and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 174 actively recruiting studies with Connecticut sites out of 174 registered in total. The busiest research areas in Connecticut are Prostate Cancer, Multiple Myeloma, Cancer. Leading sponsors running trials in the state include Yale University, National Cancer Institute (NCI), Pfizer. By stage, Connecticut trials break down as Phase 1 (39), Phase 2 (58), Phase 3 (44), Phase 4 (4).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
174
Recruiting Now
174
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Top Conditions in Connecticut
Prostate Cancer (7)Multiple Myeloma (4)Cancer (4)Colorectal Cancer (4)Solid Tumor (4)Metastatic Breast Cancer (4)Sickle Cell Disease (3)Advanced Solid Tumors (3)NSCLC (3)Advanced Solid Tumor (3)Heart Failure (3)Breast Cancer (3)

Frequently Asked Questions — Clinical Trials in Connecticut

How many clinical trials are currently recruiting in Connecticut?
ClinicalMetric currently tracks 174 actively recruiting clinical trials with at least one location in Connecticut. The total number of registered studies—including active but not currently enrolling trials—is 174. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Connecticut?
Connecticut hosts clinical trials across a broad range of medical conditions, including Prostate Cancer, Multiple Myeloma, Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Connecticut serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Connecticut?
To join a clinical trial in Connecticut, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Connecticut maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Connecticut

NCT03486873 Phase 3
Recruiting
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tum...
Condition
Solid Tumors
Enrollment
3,500 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT05465044 N/A
Recruiting
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
Condition
Chronic Kidney Disease (CKD) Stage 5
Enrollment
252 pts
Location
United States
Sponsor
VA Office of Research and Deve
View Trial →
NCT06860594 Phase 1
Recruiting
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Th...
Condition
Astrocytoma, IDH-Mutant, Grade 2
Enrollment
30 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT06988488 Phase 1, Phase 2
Recruiting
A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety ...
Condition
Multiple Myeloma
Enrollment
62 pts
Location
United States, Canada, China
Sponsor
Celgene
View Trial →
NCT07340541 Phase 2
Recruiting
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
Condition
Breast Cancer
Enrollment
700 pts
Location
United States
Sponsor
UNC Lineberger Comprehensive C
View Trial →
NCT06172296 Phase 3
Recruiting
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Tre...
Condition
Ganglioneuroblastoma, Nodular
Enrollment
478 pts
Location
United States, Australia, Canada
Sponsor
National Cancer Institute (NCI
View Trial →
NCT05923073 Phase 3
Recruiting
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Acti...
Condition
Crohn's Disease
Enrollment
120 pts
Location
United States, Australia, Austria
Sponsor
Janssen Research & Development
View Trial →
NCT04422912 Phase 1, Phase 2
Recruiting
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmo...
Condition
Pemphigus Vulgaris
Enrollment
40 pts
Location
United States
Sponsor
Cabaletta Bio
View Trial →
NCT07426757 Phase 1
Recruiting
An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancer...
Condition
Advanced Malignancies
Enrollment
120 pts
Location
United States, Canada
Sponsor
Pfizer
View Trial →
NCT04321512 N/A
Recruiting
Study of Circulating Monocytes in Patients With Ischemic Vascular Disease
Condition
Myocardial Infarction
Enrollment
300 pts
Location
United States
Sponsor
UConn Health
View Trial →
NCT07578571 Phase 1
Recruiting
A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
Condition
Colorectal Cancer
Enrollment
200 pts
Location
United States
Sponsor
Immunome, Inc.
View Trial →
NCT07689864 N/A
Recruiting
Unified Network for Integrated Fluid Collection at Yale
Condition
Molecular Residual Disease
Enrollment
2,500 pts
Location
United States
Sponsor
Yale University
View Trial →
NCT05751434 Phase 2
Recruiting
A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer
Condition
Prostate Cancer
Enrollment
102 pts
Location
United States
Sponsor
City of Hope Medical Center
View Trial →
NCT05786924 Phase 1, Phase 2
Recruiting
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Condition
Non-small Cell Lung Cancer
Enrollment
554 pts
Location
United States, Australia, China
Sponsor
Institut de Recherches Interna
View Trial →
NCT04181060 Phase 3
Recruiting
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With E...
Condition
Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Enrollment
300 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT06953960 Phase 1, Phase 2
Recruiting
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoc...
Condition
Multiple Myeloma
Enrollment
325 pts
Location
United States, Australia, Belgium
Sponsor
AbbVie
View Trial →
NCT06136559 Phase 3
Recruiting
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of I...
Condition
Chronic Lymphocytic Leukemia
Enrollment
1,200 pts
Location
United States, Australia, Belgium
Sponsor
Merck Sharp & Dohme LLC
View Trial →
NCT06445946 Phase 4
Recruiting
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Tr...
Condition
Gestational Diabetes Mellitus
Enrollment
1,572 pts
Location
United States
Sponsor
Ohio State University
View Trial →
NCT07357727 Phase 3
Recruiting
A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)
Condition
Primary Myelofibrosis (PMF)
Enrollment
460 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
View Trial →
NCT02998229 N/A
Recruiting
The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bi...
Condition
Intracranial Aneurysm
Enrollment
300 pts
Location
United States
Sponsor
Medtronic Neurovascular Clinic
View Trial →
NCT04566328 Phase 3
Recruiting
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Mu...
Condition
Plasma Cell Myeloma
Enrollment
1,450 pts
Location
United States, Puerto Rico
Sponsor
ECOG-ACRIN Cancer Research Gro
View Trial →
NCT03808337 Phase 2
Recruiting
Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addi...
Condition
Triple Negative Breast Cancer
Enrollment
145 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance
View Trial →
NCT07149740 N/A
Recruiting
Data Gathering for A10900
Condition
Retinal Disease
Enrollment
180 pts
Location
United States
Sponsor
Optos, PLC
View Trial →
NCT07589608 Phase 2
Recruiting
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone...
Condition
Overweight
Enrollment
400 pts
Location
United States
Sponsor
Eli Lilly and Company
View Trial →
NCT05992324 N/A
Recruiting
A Validation Study to Evaluate the Performance of Caption Health Lung Guidance a...
Condition
Shortness of Breath
Enrollment
220 pts
Location
United States
Sponsor
Caption Health, Inc.
View Trial →
Page 5 of 7 — 174 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology