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Medical Condition

glioma

Total Trials
16
Recruiting Now
16
Trial Phases
Phase 2, Phase 1, Phase 3

ClinicalMetric tracks all active clinical trials for glioma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — glioma Clinical Trials

How many clinical trials are currently recruiting for glioma?
ClinicalMetric currently tracks 16 actively recruiting clinical trials for glioma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 16. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for glioma?
glioma research spans Phase 1 (5 trials), Phase 2 (2 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a glioma clinical trial?
Eligibility criteria for glioma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
5
Phase 2
2
Phase 3
1
Top Sponsors
Baptist Health South Florida 1 trial
University of Milan 1 trial
Northwell Health 1 trial
Henry Ford Health System 1 trial
Nuvation Bio Inc. 1 trial

Recruiting Clinical Trials

NCT06397560
Recruiting
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial
Enrollment
28 pts
Location
United States
Sponsor
Baptist Health South Florida
View Trial →
NCT06381726
Recruiting
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life
Enrollment
400 pts
Location
Italy
Sponsor
University of Milan
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NCT02800486 Phase 2
Recruiting
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
Enrollment
37 pts
Location
United States
Sponsor
Northwell Health
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NCT05686798 Phase 1
Recruiting
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Enrollment
18 pts
Location
United States
Sponsor
Henry Ford Health System
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NCT05303519 Phase 3
Recruiting
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
Enrollment
365 pts
Location
United States, Austr...
Sponsor
Nuvation Bio Inc.
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NCT05464992
Recruiting
Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI
Enrollment
800 pts
Location
France
Sponsor
Centre Paul Strauss
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NCT06055517
Recruiting
Use of Pulsed Low-dose Rate Re-irradiation for Recurrent Glioma (PULSAR)
Enrollment
29 pts
Location
Italy
Sponsor
Centro di Riferimento Oncologi...
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NCT06610851
Recruiting
Monitoring of Patients With Low-grade Gliomas Using Circulating miRNA
Enrollment
20 pts
Location
France
Sponsor
University Hospital, Caen
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NCT05460507 Phase 1
Recruiting
Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment
Enrollment
40 pts
Location
United States
Sponsor
Plus Therapeutics
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NCT06650163 Phase 1
Recruiting
Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors
Enrollment
20 pts
Location
United States
Sponsor
Jonsson Comprehensive Cancer C...
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NCT04274283
Recruiting
Tessa Jowell BRAIN MATRIX - Platform Study
Enrollment
1,000 pts
Location
United Kingdom
Sponsor
University of Birmingham
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NCT07541781 Phase 1
Recruiting
Sitagliptin in Recurrent/Progressive Grade 4 Glioma
Enrollment
45 pts
Location
United States
Sponsor
Kailin Yang, MD, PhD
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NCT06326411 Phase 1
Recruiting
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
Enrollment
230 pts
Location
United States, Austr...
Sponsor
Nested Therapeutics, Inc
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NCT07263711
Recruiting
Prospective Real-World Study of Pathology AI for Glioma Molecular Prediction
Enrollment
2,000 pts
Location
China
Sponsor
Nanfang Hospital, Southern Med...
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NCT05607407 Phase 2
Recruiting
Methimazole in Patients With Progressive Glioblastoma
Enrollment
19 pts
Location
United States
Sponsor
Case Comprehensive Cancer Cent...
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NCT05049148
Recruiting
Platelets Activation in Brain Neoplasms
Enrollment
50 pts
Location
France
Sponsor
Fondation Ophtalmologique Adol...
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Related Conditions

glioblastoma (4) glioma malignant (2) recurrent glioma (2) brain cancer (2) brain tumor (2) anaplastic astrocytoma (1) anaplastic oligoastrocytoma (1) brain neoplasm (1) brain tumor recurrent (1) brain neoplasm malignant (1) malignant glioma of brain (1) astrocytoma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology