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Medical Condition

glioma

Total Trials

17

Recruiting Now

17

Trial Phases

Phase 4, Phase 2, Phase 1

ClinicalMetric tracks all active clinical trials for glioma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — glioma Clinical Trials

How many clinical trials are currently recruiting for glioma?

ClinicalMetric currently tracks 17 actively recruiting clinical trials for glioma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 17. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for glioma?

glioma research spans Phase 1 (6 trials), Phase 2 (3 trials), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a glioma clinical trial?

Eligibility criteria for glioma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

6

Phase 2

3

Phase 3

1

Phase 4

1

Top Sponsors

Tata Memorial Centre 2 trials

Leiden University Medical Center 1 trial

HighField Biopharmaceuticals Corporation 1 trial

Kailin Yang, MD, PhD 1 trial

Aveta Biomics, Inc. 1 trial

Recruiting Clinical Trials

NCT03048084 Phase 4

Seizure Treatment in Glioma

Leiden University Medical Cent...

NCT07678684 Phase 2

A Study of HF1K16 Combined With Bevacizumab in Patients With Recurrent or Progressive Glioma

HighField Biopharmaceuticals C...

NCT07541781 Phase 1

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

Kailin Yang, MD, PhD

NCT06011109 Phase 1, Phase 2

Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab

Aveta Biomics, Inc.

MR Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence

The First Affiliated Hospital ...

NCT06496971 Phase 3

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NaviFUS Corporation

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

Jona Hattangadi-Gluth

BIO-SHORT: Hypofractionated RT for Poor-Prognosis GBM

Tata Memorial Centre

NCT06344130 Phase 1

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

National Cancer Institute (NCI...

NCT07210632 EARLY_Phase 1

Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)

Clinical, patHOlogical and Imaging Project of nEuro-oncology (HOPE)

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

University of Maryland, Baltim...

NCT06326411 Phase 1

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

United States, Austr...

Nested Therapeutics, Inc

Craniospinal Irradiation in Histone AlteRed Midline Glioma

Tata Memorial Centre

NCT06818331 Phase 2

Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial

The Third Affiliated hospital ...

NCT03739411 Phase 1

Hyperpolarized Imaging in Diagnosing Participants With Glioma

Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients With Low Grade Gliomas

University of Ulm

Related Conditions

glioblastoma (3) brain tumor (3) recurrent glioblastoma (2) glioblastoma multiforme (2) adult (1) recurrent glioma (1) grade 4 malignant glioma of brain disorder (1) glioblastoma multiforme adult (1) brain tumor recurrent (1) neoplasms (1) neoplasms nerve tissue (1) primary brain tumor (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology