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Yale University

Total Trials
35
Recruiting
35
Phases
Phase 1, Phase 2, Phase 3, EARLY_Phase 1

Yale University is a clinical research sponsor with 35 registered studies on ClinicalTrials.gov, of which 35 are actively recruiting participants. Research covers conditions including Breast Cancer, Hyperinsulinism, HER2-negative Breast Cancer, Appendicitis.

The trial portfolio spans Phase 1, Phase 2, Phase 3 studies, reflecting a pipeline that may include early-stage safety evaluations, mid-stage efficacy assessments, and large-scale confirmatory trials. All studies listed here are sourced directly from ClinicalTrials.gov and updated daily.

Frequently Asked Questions — Yale University

How many clinical trials has Yale University sponsored?
ClinicalMetric currently tracks 35 clinical trials sponsored by Yale University, of which 35 are actively recruiting participants. These trials cover conditions including Breast Cancer, Hyperinsulinism, HER2-negative Breast Cancer. Trial counts are updated daily from ClinicalTrials.gov and reflect currently registered studies.
What therapeutic areas does Yale University research focus on?
Yale University clinical trials span Breast Cancer, Hyperinsulinism, HER2-negative Breast Cancer, Appendicitis, Depression, and additional conditions. The research pipeline includes Phase 1, Phase 2, Phase 3 trials, reflecting work from early-stage safety evaluation through large-scale efficacy studies.
How do I participate in a Yale University clinical trial?
To participate in a Yale University trial, review the active studies listed on this page, check each trial's specific eligibility criteria on ClinicalTrials.gov, and contact the trial site directly—not the sponsor's headquarters. Trial sites are academic medical centers, hospitals, or specialized research clinics. Your physician can facilitate a referral. ClinicalMetric lists all Yale University trials with current recruitment status updated daily.

Clinical Trials by Yale University

NCT05989347 Phase 1
Recruiting

Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy

Breast Cancer
NCT04168866
Recruiting

Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon

Appendicitis
NCT07610369 Phase 2
Recruiting

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

Depression
NCT05743673
Recruiting

SHAPE Test for Preoperative Risk Stratification

Perioperative/Postoperative Complications
NCT02491099 Phase 2
Recruiting

A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma

HER2/Neu+ Uterine Serous Carcinoma
NCT06111781 Phase 2
Recruiting

The SUGAR Study; SBRT and Relugolix) for Prostate Cancer

Prostate Cancer
NCT07291180
Recruiting

A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis

Appendiceal Cancer
NCT07019259
Recruiting

Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

Cancer
NCT05726032 Phase 2
Recruiting

Empagliflozin in Patients With Cirrhosis and Ascites

Cirrhosis
NCT05915013 Phase 1
Recruiting

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Depressive Disorder, Major
NCT07398976
Recruiting

Sex Differences in E-Cigarette Perception

Nicotine Dependence
NCT05551325
Recruiting

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

Critical Illness
NCT06172660
Recruiting

Real-World Effectiveness of Perinatal RSV Immunoprophylaxis

RSV Infection
NCT06122246
Recruiting

PRESSURE CHECK: Find Your Path to Better Health

Blood Pressure
NCT06830174
Recruiting

tDCS for Laryngeal Dystonia

Laryngeal Dystonia
NCT07201402 Phase 2
Recruiting

Long Term Evaluation of Scapular-inserted Contraceptive Implants

Contraception
NCT04974671 Phase 2
Recruiting

Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma
NCT06494904 Phase 3
Recruiting

Standard Versus High Dose ED-Initiated Buprenorphine Induction

Opioid Use Disorder
NCT06462430
Recruiting

PTEN Hamartoma Tumor Syndrome Pediatric Patient Registry

PTEN Hamartoma Tumor Syndrome
NCT06407427
Recruiting

Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation

Spine Degeneration
NCT07407023
Recruiting

PoRI Clinical Trial

Post Stroke
NCT07113691 Phase 1
Recruiting

Iadademstat + SBRT With Atezo in ES-SCLC

Extensive Stage Small Cell Lung Cancer (ES-SCLC)
NCT06371404
Recruiting

Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat

Alcohol Use Disorder
NCT06684613 Phase 2
Recruiting

Integrating PrEP Decision Making Into Counseling in Sexual and Reproductive Health Clinics

Sexual Risk Behavior for HIV-infection
NCT06329453
Recruiting

Intestinal Immunity in Neurologic Disease

Multiple Sclerosis
NCT04366518 EARLY_Phase 1
Recruiting

Toward a Computationally-Informed, Personalized Treatment for Hallucinations

Hallucinations, Auditory
NCT07457736 EARLY_Phase 1
Recruiting

Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1

Healthy Adult Participants
NCT07040592 Phase 2
Recruiting

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

Alcohol Use Disorder (AUD)
NCT04355572
Recruiting

Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)

Polycystic Ovarian Syndrome in Adolescent Females
NCT05781009 Phase 2
Recruiting

Pregnenolone for the Treatment of Alcohol Use Disorder

Alcohol Use Disorder
NCT06650267 Phase 2
Recruiting

Substance Misuse and Family Violence Treatment Fathers

Substance Misuse
NCT03995121
Recruiting

SV2 PET Imaging With [11C]APP311

Schizophrenia and Other Psychotic Disorders
NCT06467305
Recruiting

Speech Motor Learning and Retention (Aim 1)

Speech
NCT07488819
Recruiting

Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974

Post-Traumatic Stress Disorder, PTSD
NCT05827159 Phase 3
Recruiting

Emergency Department-Initiated Medications for Alcohol Use Disorder

Alcohol Use Disorder
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology