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Recruiting Phase 1 NCT02811510

NCT02811510 Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I

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Clinical Trial Summary
NCT ID NCT02811510
Status Recruiting
Phase Phase 1
Sponsor Yale University
Condition Cannabis
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2016-06
Primary Completion 2026-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 55 Years
Study Type INTERVENTIONAL
Interventions
PlaceboDronabinol

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.

This trial targets 40 participants in total. It began in 2016-06 with a primary completion date of 2026-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.

Eligibility Criteria

Inclusion Criteria: * At least one lifetime exposure to cannabis * Good physical and mental health Exclusion Criteria: * Cannabis naive individuals * Major current or recent stressors * Taking estrogen supplements or oral contraceptive pills (for women) * Sesame oil allergy

Contact & Investigator

Central Contact

Carly Hewes, BS

✉ carly.hewes@yale.edu

📞 (203)932-5711

Frequently Asked Questions

Who can join the NCT02811510 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 55 Years, studying Cannabis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT02811510 trial and what does that mean for participants?

Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.

Is NCT02811510 currently recruiting?

Yes, NCT02811510 is actively recruiting participants. Contact the research team at carly.hewes@yale.edu for enrollment information.

Where is the NCT02811510 trial being conducted?

This trial is being conducted at West Haven, United States.

Who is sponsoring the NCT02811510 clinical trial?

NCT02811510 is sponsored by Yale University. The trial plans to enroll 40 participants.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology