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Recruiting NCT06533631
Measuring Brain Health Using Low-Field Portable MRI
Trial Parameters
Condition White Matter Hyperintensity
Sponsor Yale University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 50 Years
Max Age N/A
Start Date 2025-02-05
Completion 2026-11
Interventions
Portable low-field MRI (pMRI)3T MRI
Brief Summary
The purpose of this study is to develop a new grading scale and utilize automated segmentation for measurement of White Matter Hyperintensity (WMH) volume using a low field MRI.
Eligibility Criteria
Inclusion Criteria: * One vascular risk factor, from the following: 1. Hypertension (defined as taking an antihypertensive medication) 2. Hyperlipidemia (defined as taking a statin or PCSK9 inhibitor) 3. Diabetes (defined as taking a medication to prevent hyperglycemia) Exclusion Criteria: * 1\. History of stroke * History of dementia or other cognitive impairment * Pacemaker or other MRI contraindications according to the American College of Radiology guidelines