Browse by Phase
Phase 1 / Phase 2 Clinical Trials
Phase 1/2 combined trials evaluate both safety (Phase 1) and preliminary efficacy (Phase 2) in a single study protocol, often used to accelerate early development.
Total Trials
361
Recruiting Now
361
Top Conditions in Phase 1 / Phase 2
NCT03761108 Phase 1, Phase 2
Recruiting
Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory M...
Condition
Multiple Myeloma
Enrollment
387 pts
Location
United States, Belgium, Germany
Sponsor
Regeneron Pharmaceuticals
NCT06349590 Phase 1, Phase 2
Recruiting
Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Preven...
Condition
Colorectal Cancer
Enrollment
80 pts
Location
United States
Sponsor
University of Chicago
NCT06957327 Phase 1, Phase 2
Recruiting
A Study of ERAS-601 in People With Chordoma
Condition
Chordoma
Enrollment
46 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance
NCT07204574 Phase 1, Phase 2
Recruiting
The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Saf...
Condition
CRC
Enrollment
40 pts
Location
Taiwan
Sponsor
Chang Gung Memorial Hospital
NCT05230459 Phase 1, Phase 2
Recruiting
A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With...
Condition
Limb Girdle Muscular Dystrophy
Enrollment
10 pts
Location
United States
Sponsor
AskBio Inc
NCT06237179 Phase 1, Phase 2
Recruiting
Behavioral Exercise Training to Reduce Cardiovascular Disease Risk
Condition
Prostate Cancer
Enrollment
60 pts
Location
United States
Sponsor
Virginia Commonwealth Universi
NCT03067051 Phase 1, Phase 2
Recruiting
Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
Condition
Recurrent Prostate Cancer
Enrollment
66 pts
Location
United States, Canada, Sweden
Sponsor
SpectraCure AB
NCT04328337 Phase 1, Phase 2
Recruiting
Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Gluco...
Condition
Obesity
Enrollment
40 pts
Location
United States
Sponsor
University of North Carolina,
NCT06953960 Phase 1, Phase 2
Recruiting
A Study to Assess Adverse Events and Change in Disease Activity of Oral ABBV-453...
Condition
Multiple Myeloma
Enrollment
130 pts
Location
United States, Australia, Belgium
Sponsor
AbbVie
NCT05878860 Phase 1, Phase 2
Recruiting
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
Condition
X-linked Retinoschisis
Enrollment
21 pts
Location
United States
Sponsor
Atsena Therapeutics Inc.
NCT06903559 Phase 1, Phase 2
Recruiting
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patien...
Condition
Kidney Failure, Chronic
Enrollment
46 pts
Location
Egypt
Sponsor
Mansoura University
NCT06471946 Phase 1, Phase 2
Recruiting
VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS
Condition
Higher-risk Myelodysplastic Syndromes
Enrollment
54 pts
Location
China
Sponsor
Navy General Hospital, Beijing
NCT06255782 Phase 1, Phase 2
Recruiting
An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of...
Condition
Ornithine Transcarbamylase Deficiency
Enrollment
8 pts
Location
United States, Australia, Spain
Sponsor
iECURE, Inc.
NCT07480954 Phase 1, Phase 2
Recruiting
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)
Condition
Epithelial Ovarian Cancer
Enrollment
36 pts
Location
China
Sponsor
Beijing Biotech
NCT06675422 Phase 1, Phase 2
Recruiting
JY231 Injection for the Treatment of Active Systemic Lupus Erythematosus (SLE)
Condition
Systemic Lupus Erythematosus (SLE)
Enrollment
20 pts
Location
China
Sponsor
920th Hospital of Joint Logist
NCT07182279 Phase 1, Phase 2
Recruiting
Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patie...
Condition
Prostate Cancer (Adenocarcinoma)
Enrollment
29 pts
Location
United States
Sponsor
The Methodist Hospital Researc
NCT03934905 Phase 1, Phase 2
Recruiting
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Ass...
Condition
Anthracycline Related Cardiotoxicity in Breast Cancer
Enrollment
70 pts
Location
United States
Sponsor
Texas Tech University Health S
NCT06616389 Phase 1, Phase 2
Recruiting
Study of ODX (OsteoDex) in Multiple Myeloma
Condition
Multiple Myeloma
Enrollment
12 pts
Location
Sweden
Sponsor
DexTech Medical AB
NCT04906460 Phase 1, Phase 2
Recruiting
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWA...
Condition
Duchenne Muscular Dystrophy
Enrollment
26 pts
Location
United States, Jordan, United Kingdom
Sponsor
Wave Life Sciences Ltd.
NCT07087223 Phase 1, Phase 2
Recruiting
Phase Ib/II Study of Vebreltinib With Furmonertinib in NSCLC Patients With c-Met...
Condition
Non Small Cell Lung Cancer NSCLC
Enrollment
42 pts
Location
China
Sponsor
Peking University Cancer Hospi
NCT06329973 Phase 1, Phase 2
Recruiting
Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment f...
Condition
Metastatic Gastroesophageal Junction Adenocarcinoma
Enrollment
70 pts
Location
China
Sponsor
Henan Cancer Hospital
NCT04750122 Phase 1, Phase 2
Recruiting
Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for HER2 Positive Ea...
Condition
HER2-positive Early Breast Cancer
Enrollment
46 pts
Location
China
Sponsor
Peking University People's Hos
NCT06776510 Phase 1, Phase 2
Recruiting
A Clinical Study of NAD in the Treatment of Immune Thrombocytopenia
Condition
Immune Thrombocytopenia
Enrollment
20 pts
Location
China
Sponsor
Institute of Hematology & Bloo
NCT04923542 Phase 1, Phase 2
Recruiting
Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cance...
Condition
Brain Metastases
Enrollment
31 pts
Location
United States
Sponsor
H. Lee Moffitt Cancer Center a
NCT07356154 Phase 1, Phase 2
Recruiting
A Study of Revumenib and Mezigdomide in People With Leukemia
Condition
Leukemia
Enrollment
52 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance