Medical Condition

low back pain

Total Trials

9

Recruiting Now

9

Trial Phases

Phase 2

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain — each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — low back pain Clinical Trials

How many clinical trials are currently recruiting for low back pain?

ClinicalMetric currently tracks 9 actively recruiting clinical trials for low back pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for low back pain?

low back pain research spans Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a low back pain clinical trial?

Eligibility criteria for low back pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

University of Valencia

View Trial →

NCT06469905

Recruiting

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology

low back pain

Frequently Asked Questions — low back pain Clinical Trials

Recruiting Clinical Trials

Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers

Online Versus Physically Supervised Pilates Exercise Program in Non-specific Low Back Pain

Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)

Efficacy and Duration of Pain Relief in Transforaminal and Lumbar Sympathetic Blocks

Post Isometric Relaxation Versus Post Facilitation Stretch Techniques in Chronic Low Back Pain

Telerehabilitation-based Exercises vs Standard Home-based Exercise in Low Back Pain

Erector Spina Plan Block in Patients With Lumbar Disc Herniation

The Spine Phenome Project

Exercise Effects on Fascia, Low Back Pain, and Function in Scoliosis