← Browse by Condition
Medical Condition

low back pain

Total Trials
15
Recruiting Now
15
Trial Phases
Various

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — low back pain Clinical Trials

How many clinical trials are currently recruiting for low back pain?
ClinicalMetric currently tracks 15 actively recruiting clinical trials for low back pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 15. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for low back pain?
low back pain research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a low back pain clinical trial?
Eligibility criteria for low back pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Riphah International University 5 trials
Kuopio University Hospital 1 trial
Istanbul Medipol University Hospital 1 trial
Sohag University 1 trial
Jaseng Hospital of Korean Medicine 1 trial

Recruiting Clinical Trials

NCT07576244
Recruiting
Effects of Core Stabilization Exercises and Myofascial Induction Therapy in Postpartum Low-back Pain
Enrollment
40 pts
Location
Pakistan
Sponsor
Riphah International Universit...
View Trial →
NCT07795697
Recruiting
Telerehabilitation After Spine Surgery
Enrollment
300 pts
Location
Finland
Sponsor
Kuopio University Hospital
View Trial →
NCT06987175
Recruiting
Effects of Sedante Neo Therapy on Pain, Range of Motion and Quality of Life in Patients With Non Specific Low Back Pain.
Enrollment
40 pts
Location
Pakistan
Sponsor
Riphah International Universit...
View Trial →
NCT07856498
Recruiting
Pain Catastrophizing, Fear of Movement, and Physical Activity in Postmenopausal Women With Chronic Low Back Pain
Enrollment
150 pts
Location
Turkey (Türkiye)
Sponsor
Istanbul Medipol University Ho...
View Trial →
NCT06766240
Recruiting
the Role of MRI in Evaluation of Low Back Pain
Enrollment
50 pts
Location
Egypt
Sponsor
Sohag University
View Trial →
NCT02257723
Recruiting
The Effect of Integrated CAM Treatment in Hospitalized Patients
Enrollment
100,000 pts
Location
South Korea
Sponsor
Jaseng Hospital of Korean Medi...
View Trial →
NCT07205991
Recruiting
ADHERE Trial: Strategies to Improve Mobile App Adherence
Enrollment
258 pts
Location
Australia
Sponsor
Neuroscience Research Australi...
View Trial →
NCT06584721
Recruiting
Short Foot Exercises and Anti-pronation Taping on Low Back Pain Associated With Hyper Pronation
Enrollment
40 pts
Location
Pakistan
Sponsor
Riphah International Universit...
View Trial →
NCT07467070
Recruiting
Effectiveness of Pilates on Postural Correction, Core Strength and Flexibility in Younger Individuals With Non-specific Low Backache
Enrollment
50 pts
Location
Pakistan
Sponsor
University of Health Sciences ...
View Trial →
NCT06030570
Recruiting
Effect of an Interdisciplinary Spine Rehabilitation Program
Enrollment
90 pts
Location
Belgium
Sponsor
KU Leuven
View Trial →
NCT07595718
Recruiting
AI-Based Phenome Data Analysis for Predicting the Onset of Major Diseases
Enrollment
1,000 pts
Location
South Korea
Sponsor
Jae Yong Jeon, MD
View Trial →
NCT04226716
Recruiting
The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain
Enrollment
192 pts
Location
Belgium
Sponsor
Hasselt University
View Trial →
NCT06985849
Recruiting
Effects of Feldenkrais and Otago Exercise Protocols for Mechanical Low Back Pain
Enrollment
36 pts
Location
Pakistan
Sponsor
Riphah International Universit...
View Trial →
NCT04783454
Recruiting
Preventing Neck & Back Pain in Teleworking Office Workers: a Randomized Controlled Trial
Enrollment
600 pts
Location
Belgium
Sponsor
University Ghent
View Trial →
NCT07426562
Recruiting
Post Facilitatiion Stretch and Dry Needling on Hamstring Tightness in Chronic Low Back Pain
Enrollment
36 pts
Location
Pakistan
Sponsor
Riphah International Universit...
View Trial →

Related Conditions

neck pain (2) spine surgery (1) telerehabilitation (1) range of motion (1) pain (1) postmenopause women (1) knee pain (1) shoulder pain (1) intervertebral disc herniation (1) spinal stenosis (1) postural control (1) core strength (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology