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Medical Condition
chronic low back pain
Total Trials
12
Recruiting Now
12
Trial Phases
Various
Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.
Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.
Frequently Asked Questions — chronic low back pain Clinical Trials
How many clinical trials are currently recruiting for chronic low back pain?
ClinicalMetric currently tracks 12 actively recruiting clinical trials for chronic low back pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for chronic low back pain?
chronic low back pain research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a chronic low back pain clinical trial?
Eligibility criteria for chronic low back pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT04730700
Recruiting
Enrollment
50 pts
Location
United States
Sponsor
University of Kansas Medical C...
NCT05953155
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Enrollment
110 pts
Location
Brazil
Sponsor
Federal University of Minas Ge...
NCT06106191
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Enrollment
350 pts
Location
United States
Sponsor
Boston Medical Center
NCT06825390
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Enrollment
60 pts
Location
United States
Sponsor
Keith M Vogt
NCT06751160
Recruiting
Enrollment
30 pts
Location
Pakistan
Sponsor
Riphah International Universit...
NCT06940063
Recruiting
Enrollment
40 pts
Location
United States
Sponsor
Sharon Wang-Price
NCT06796881
Recruiting
Enrollment
66 pts
Location
Egypt
Sponsor
Cairo University
NCT06471920
Recruiting
Enrollment
434 pts
Location
United States
Sponsor
Johns Hopkins University
NCT07760142
Recruiting
Enrollment
45 pts
Location
Turkey (Türkiye)
Sponsor
Uskudar University
NCT04658628
Recruiting
Enrollment
42 pts
Location
United States
Sponsor
University of California, Los ...
NCT07141082
Recruiting
Enrollment
30 pts
Location
Hong Kong
Sponsor
The Hong Kong Polytechnic Univ...
NCT04853732
Recruiting
Enrollment
10,000 pts
Location
United States
Sponsor
University of North Texas Heal...
Related Conditions
low back pain (2) back pain lower back chronic (2) back pain (1) back pain low (1) lumbar disc disease (1) lumbar discogenic pain (1) lumbar pain syndrome (1) lumbar post laminectomy syndrome (1) back pain without radiation (1) pain back low chronic (1) hamstring tightness (1) myofascial release (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology