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Medical Condition
chronic low back pain
Total Trials
9
Recruiting Now
9
Trial Phases
Phase 2
Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.
Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.
Frequently Asked Questions — chronic low back pain Clinical Trials
How many clinical trials are currently recruiting for chronic low back pain?
ClinicalMetric currently tracks 9 actively recruiting clinical trials for chronic low back pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for chronic low back pain?
chronic low back pain research spans Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a chronic low back pain clinical trial?
Eligibility criteria for chronic low back pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2 1
Top Sponsors
2 trials
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT07681336
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Enrollment
44 pts
Location
Belgium
Sponsor
Algemeen Ziekenhuis Maria Midd...
NCT07415941
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66 pts
Location
United States
Sponsor
Florida State University
NCT07772141
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Enrollment
106 pts
Location
Egypt
Sponsor
Beni-Suef University
NCT06568198 Phase 2
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Enrollment
80 pts
Location
United States
Sponsor
Massachusetts General Hospital
NCT07731750
Recruiting
Enrollment
500 pts
Location
United States
Sponsor
University of Michigan
NCT06796881
Recruiting
Enrollment
66 pts
Location
Egypt
Sponsor
Cairo University
NCT06080464
Recruiting
Enrollment
360 pts
Location
United States
Sponsor
University of Michigan
NCT07463105
Recruiting
Enrollment
80 pts
Location
Poland
Sponsor
University of Rzeszow
NCT05963451
Recruiting
Enrollment
80 pts
Location
Canada
Sponsor
Université de Sherbrooke
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology