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Recruiting NCT07003113

NCT07003113 Ischemic Preconditioning in Osteoarthritis and Back Pain

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Clinical Trial Summary
NCT ID NCT07003113
Status Recruiting
Phase
Sponsor University of Illinois at Chicago
Condition Low Back Pain
Study Type INTERVENTIONAL
Enrollment 24 participants
Start Date 2025-09-12
Primary Completion 2026-07-31

Eligibility & Interventions

Sex All sexes
Min Age 50 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Ischemic PreconditioningSham Intervention

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 24 participants in total. It began in 2025-09-12 with a primary completion date of 2026-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

Eligibility Criteria

Inclusion Criteria: * Reported Knee Pain using ACR Criteria * Reported Back Pain using ODI Criteria \> 12 * Ability to walk for at least 3 minutes without the use of aids * Ability to provide written informed consent Exclusion Criteria: * Younger than 50 years old * History of Knee or Hip Replacements * History of steroid injection within the previous 6 months * Presence of neuromuscular joint condition that affects lower extremity function * History of blood clots in the leg or any condition in which compression of the thigh is contraindicated * History of heart failure or thrombosis * Allergic to ultrasound gel * History of spine surgery * Non-English speaker * Currently pregnant or intends to become pregnant during the study

Contact & Investigator

Central Contact

Shraddha Sudhir

✉ ssudhi5@uic.edu

📞 312-413-5118

Principal Investigator

Lindsay Hannigan

PRINCIPAL INVESTIGATOR

University of Illinois at Chicago

Frequently Asked Questions

Who can join the NCT07003113 clinical trial?

This trial is open to participants of all sexes, aged 50 Years or older, studying Low Back Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07003113 currently recruiting?

Yes, NCT07003113 is actively recruiting participants. Contact the research team at ssudhi5@uic.edu for enrollment information.

Where is the NCT07003113 trial being conducted?

This trial is being conducted at Chicago, United States.

Who is sponsoring the NCT07003113 clinical trial?

NCT07003113 is sponsored by University of Illinois at Chicago. The principal investigator is Lindsay Hannigan at University of Illinois at Chicago. The trial plans to enroll 24 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology