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chronic low back pain clbp

Total Trials
6
Recruiting Now
6
Trial Phases
Various

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — chronic low back pain clbp Clinical Trials

How many clinical trials are currently recruiting for chronic low back pain clbp?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for chronic low back pain clbp, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for chronic low back pain clbp?
chronic low back pain clbp research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a chronic low back pain clbp clinical trial?
Eligibility criteria for chronic low back pain clbp trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Taif University 1 trial
Laval University 1 trial
Edward Hines Jr. VA Hospital 1 trial
The Hong Kong Polytechnic University 1 trial
Lahore University of Biological and Applied Sciences 1 trial

Recruiting Clinical Trials

NCT06963658
Recruiting

Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain

Enrollment
90 pts
Location
Saudi Arabia
Sponsor
Taif University
View Trial →
NCT06999772
Recruiting

Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain

Enrollment
96 pts
Location
Canada
Sponsor
Laval University
View Trial →
NCT07161661
Recruiting

Chronic Low Back Pain and Osteopathic Manipulation Treatment

Enrollment
48 pts
Location
United States
Sponsor
Edward Hines Jr. VA Hospital
View Trial →
NCT07211464
Recruiting

Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomised Controlled Trial

Enrollment
100 pts
Location
Hong Kong
Sponsor
The Hong Kong Polytechnic Univ...
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NCT07280806
Recruiting

Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain

Enrollment
80 pts
Location
Pakistan
Sponsor
Lahore University of Biologica...
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NCT07193212
Recruiting

How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain

Enrollment
20 pts
Location
United States
Sponsor
Edward Via Virginia College of...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology