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chronic low back pain clbp

Total Trials
6
Recruiting Now
6
Trial Phases
EARLY_Phase 1

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — chronic low back pain clbp Clinical Trials

How many clinical trials are currently recruiting for chronic low back pain clbp?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for chronic low back pain clbp, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for chronic low back pain clbp?
chronic low back pain clbp research spans Phase 1 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a chronic low back pain clbp clinical trial?
Eligibility criteria for chronic low back pain clbp trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Top Sponsors
Taif University 1 trial
University of California, Davis 1 trial
University of California, San Diego 1 trial
University Health Network, Toronto 1 trial
Weill Medical College of Cornell University 1 trial

Recruiting Clinical Trials

NCT06963658
Recruiting
Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain
Enrollment
90 pts
Location
Saudi Arabia
Sponsor
Taif University
View Trial →
NCT07494162
Recruiting
Imaging Metabolic and Perfusion Changes in Acupuncture Therapy for Myofascial Pain Syndrome
Enrollment
64 pts
Location
United States
Sponsor
University of California, Davi...
View Trial →
NCT04982965 EARLY_Phase 1
Recruiting
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Enrollment
100 pts
Location
United States
Sponsor
University of California, San ...
View Trial →
NCT07696741
Recruiting
PRT for Chronic Low Back Pain
Enrollment
30 pts
Location
Canada
Sponsor
University Health Network, Tor...
View Trial →
NCT07386548
Recruiting
Biologic Injection For Adults With Lumbar Disc Herniation
Enrollment
90 pts
Location
United States
Sponsor
Weill Medical College of Corne...
View Trial →
NCT07215104
Recruiting
A Prospective Evaluation of Spinal Cord Induced Muscle Stimulation (MuscleSCS) for the Treatment of Chronic Low Back Pain
Enrollment
30 pts
Location
United States
Sponsor
Saint Francis Hospital
View Trial →

Related Conditions

degenerative disc disease (2) degenerative disc disease lumbar (2) myofascial pain syndrome mps (1) sciatica (1) lumbar radiculopathy (1) lower back pain (1) chronic low back and leg pain (1) back pain (1) nociplastic pain (1) ddd (1) lumbar disc herniation (1) disc herniation lumbar (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology