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degenerative disc disease

Total Trials
6
Recruiting Now
6
Trial Phases
EARLY_Phase 1, Phase 3

ClinicalMetric tracks all active clinical trials for degenerative disc disease sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — degenerative disc disease Clinical Trials

How many clinical trials are currently recruiting for degenerative disc disease?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for degenerative disc disease, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for degenerative disc disease?
degenerative disc disease research spans Phase 1 (1 trial), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a degenerative disc disease clinical trial?
Eligibility criteria for degenerative disc disease trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 3
1
Top Sponsors
University of California, San Diego 1 trial
BACKBONE 1 trial
VB Spine, LLC 1 trial
DiscGenics, Inc. 1 trial
University of Colorado, Denver 1 trial

Recruiting Clinical Trials

NCT04982965 EARLY_Phase 1
Recruiting
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Enrollment
100 pts
Location
United States
Sponsor
University of California, San ...
View Trial →
NCT04631133
Recruiting
LISA Post Market Clinical Follow-Up Study: Documentation of Clinical Outcomes After Surgery With LISA Implant
Enrollment
136 pts
Location
Denmark, France, Ger...
Sponsor
BACKBONE
View Trial →
NCT06226272
Recruiting
Clinical Outcome Measure at Stryker Spine
Enrollment
5,222 pts
Location
United States
Sponsor
VB Spine, LLC
View Trial →
NCT07254806 Phase 3
Recruiting
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
Enrollment
162 pts
Location
United States
Sponsor
DiscGenics, Inc.
View Trial →
NCT04601363
Recruiting
Personalized Spine Study Group (PSSG) Registry
Enrollment
1,000 pts
Location
United States
Sponsor
University of Colorado, Denver
View Trial →
NCT04467944
Recruiting
Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery
Enrollment
210 pts
Location
China
Sponsor
Peking University Third Hospit...
View Trial →

Related Conditions

sciatica (1) lumbar radiculopathy (1) lower back pain (1) chronic low back pain clbp (1) chronic low back and leg pain (1) back pain (1) chronic low back pain (1) herniated disc (1) lumbar canal stenosis (1) degenerative scoliosis (1) scoliosis adolescence (1) spinal fusion (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology