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degenerative disc disease

Total Trials
6
Recruiting Now
6
Trial Phases
EARLY_Phase 1, Phase 3

ClinicalMetric tracks all active clinical trials for degenerative disc disease sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — degenerative disc disease Clinical Trials

How many clinical trials are currently recruiting for degenerative disc disease?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for degenerative disc disease, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for degenerative disc disease?
degenerative disc disease research spans Phase 1 (1 trial), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a degenerative disc disease clinical trial?
Eligibility criteria for degenerative disc disease trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 3
1
Top Sponsors
Collagen Matrix 1 trial
University of California, San Diego 1 trial
Weill Medical College of Cornell University 1 trial
Kuros Biosurgery AG 1 trial
CGBio Inc. 1 trial

Recruiting Clinical Trials

NCT04775537
Recruiting
OssiMend BA in Posterolateral Instrumented Lumbar Fusion
Enrollment
120 pts
Location
United States
Sponsor
Collagen Matrix
View Trial →
NCT04982965 EARLY_Phase 1
Recruiting
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Enrollment
100 pts
Location
United States
Sponsor
University of California, San ...
View Trial →
NCT07386548
Recruiting
Biologic Injection For Adults With Lumbar Disc Herniation
Enrollment
90 pts
Location
United States
Sponsor
Weill Medical College of Corne...
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NCT05037968
Recruiting
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Enrollment
100 pts
Location
United States
Sponsor
Kuros Biosurgery AG
View Trial →
NCT07017634 Phase 3
Recruiting
Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease
Enrollment
316 pts
Location
United States
Sponsor
CGBio Inc.
View Trial →
NCT05238740
Recruiting
Comparison of Radiographic Fusion Rate and Clinical Outcome of ALIF and XLIF Performed With Either Recombinant Human Bone Morphogenetic Protein-2 or ViviGen®
Enrollment
168 pts
Location
Switzerland
Sponsor
Lindenhofgruppe AG
View Trial →

Related Conditions

chronic low back pain clbp (2) degenerative disc disease lumbar (2) spinal disease (1) sciatica (1) lumbar radiculopathy (1) lower back pain (1) chronic low back and leg pain (1) back pain (1) ddd (1) lumbar disc herniation (1) disc herniation lumbar (1) bone marrow aspirate concentrate (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology