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Recruiting Phase 1 NCT06498713

Patient Controlled Administration of Liquid Acetaminophen

Trial Parameters

Condition Pain
Sponsor Yale University
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 24
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-11-19
Completion 2025-12
Interventions
Acetaminophen 650 mg Oral TabletAcetaminophen 650mg LiquidCADD pump

Brief Summary

This is a proof of concept pilot study investigating the feasibility and acceptability of patient controlled oral medication administration, using the commonly used and low risk medication in the hospital, oral acetaminophen.

Eligibility Criteria

Inclusion Criteria: Participants * Adult patients older than 18 years old admitted to SRC for total shoulder and reverse total shoulder arthroplasty Nurses * The nurse who will administer acetaminophen to a study patient. Exclusion Criteria: Participants * Pregnant patient * Patients that cannot swallow pills or cannot take liquid (for example due to risk of aspiration) * Emergency surgery * Chronic pain * On home opioids, any other pain modulating medications including benzodiazepine, Neurontin, ketamine. * Past medical or social history of substance abuse disorder, including ethanol misuse disorder, marijuana misuse disorder * History of any psychiatric disorders including anxiety, depression, any cognitive dysfunction * Any patients who cannot provide informed consents on their own (those who would need Legally Authorized Representatives (LARs) or surrogates) * Liver dysfunction limiting amount of safe oral acetaminophen * baseline hyperbilirubinemia (ex: chronic liver disease, Gilb

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