← Back to Clinical Trials
Recruiting Phase 3 NCT06144164

NCT06144164 A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT06144164
Status Recruiting
Phase Phase 3
Sponsor Memorial Sloan Kettering Cancer Center
Condition Lymphedema
Study Type INTERVENTIONAL
Enrollment 285 participants
Start Date 2023-11-16
Primary Completion 2030-03-16

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
Immediate Lymphatic ReconstructionVolumetric arm measurementsLymphatic massage

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 3 trials are large pivotal studies comparing the treatment to current standard of care or placebo. Your participation directly contributes to the evidence needed for regulatory approval.

This trial targets 285 participants in total. It began in 2023-11-16 with a primary completion date of 2030-03-16.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.

Eligibility Criteria

Inclusion Criteria: * Female sex * Diagnosis of breast cancer * Ages 18 to 75 years * Consented for unilateral ALND or for unilateral SLNB with possible ALND Exclusion Criteria: * Male sex * Does not speak English * Does not fit into study garment * Axillary recurrence * History of ALND * Requirement of bilateral ALND for the treatment of breast cancer * Treatment with SLNB only * Known anaphylactic allergy to ICG dye used in ILR * Impaired decision-making capacity

Contact & Investigator

Central Contact

Michelle Coriddi, MD

✉ coriddim@mskcc.org

📞 646-608-8042

Principal Investigator

Michelle Coriddi, MD

PRINCIPAL INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Frequently Asked Questions

Who can join the NCT06144164 clinical trial?

This trial is open to female participants only, aged 18 Years or older, up to 75 Years, studying Lymphedema. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06144164 trial and what does that mean for participants?

Phase 3 trials are large-scale studies comparing the new treatment to existing standards of care or a placebo. They provide the evidence needed for regulatory approval. This trial targets 285 participants.

Is NCT06144164 currently recruiting?

Yes, NCT06144164 is actively recruiting participants. Contact the research team at coriddim@mskcc.org for enrollment information.

Where is the NCT06144164 trial being conducted?

This trial is being conducted at Basking Ridge, United States, Middletown, United States, Montvale, United States, Commack, United States and 3 additional locations.

Who is sponsoring the NCT06144164 clinical trial?

NCT06144164 is sponsored by Memorial Sloan Kettering Cancer Center. The principal investigator is Michelle Coriddi, MD at Memorial Sloan Kettering Cancer Center. The trial plans to enroll 285 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology