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lymphedema

Total Trials
10
Recruiting Now
10
Trial Phases
Phase 3, Phase 2

ClinicalMetric tracks all active clinical trials for lymphedema sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — lymphedema Clinical Trials

How many clinical trials are currently recruiting for lymphedema?
ClinicalMetric currently tracks 10 actively recruiting clinical trials for lymphedema, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 10. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for lymphedema?
lymphedema research spans Phase 2 (2 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a lymphedema clinical trial?
Eligibility criteria for lymphedema trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
2
Phase 3
1
Top Sponsors
Koya Medical, Inc. 2 trials
M.D. Anderson Cancer Center 2 trials
Memorial Sloan Kettering Cancer Center 1 trial
University of Aarhus 1 trial
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital 1 trial

Recruiting Clinical Trials

NCT04888975
Recruiting

A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of the Dayspring Technology for Patients With Breast Cancer Related Lymphedema (BCRL) After Lymphatic Surgery

Enrollment
20 pts
Location
United States
Sponsor
Koya Medical, Inc.
View Trial →
NCT06144164 Phase 3
Recruiting

A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

Enrollment
285 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT06325618
Recruiting

Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome

Enrollment
150 pts
Location
Denmark
Sponsor
University of Aarhus
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NCT07472543
Recruiting

Impact of Virtual Reality (VR) Based Exercises on Lower Limb Lymphedema Outcomes (LELO)

Enrollment
40 pts
Location
Turkey (Türkiye)
Sponsor
Gaziler Physical Medicine and ...
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NCT05628948
Recruiting

Vascular Lab Resource (VLR) Biorepository

Enrollment
500 pts
Location
United States
Sponsor
The Cleveland Clinic
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NCT06494111 Phase 2
Recruiting

Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)

Enrollment
295 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
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NCT06989099 Phase 2
Recruiting

Lymphedema Prevention Through Immediate Lymphatic Reconstruction (LILY) Trial.

Enrollment
50 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
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NCT06235463
Recruiting

Pedal Pump and Leg Lymphedema

Enrollment
72 pts
Location
United States
Sponsor
Rowan University
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NCT01521741
Recruiting

Prospective Screening for Breast Cancer-related Lymphedema

Enrollment
10,000 pts
Location
United States
Sponsor
Massachusetts General Hospital
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NCT06418282
Recruiting

Clinical Study to Evaluate the Effectiveness and Health Economics of a Novel Portable Non-Pneumatic Active Compression Device (NPCD) for Lymphedema/Phlebolymphedema

Enrollment
100 pts
Location
United States
Sponsor
Koya Medical, Inc.
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology