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Recruiting NCT06325618

Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome

Trial Parameters

Condition Turner Syndrome
Sponsor University of Aarhus
Study Type OBSERVATIONAL
Phase N/A
Enrollment 150
Sex FEMALE
Min Age 18 Years
Max Age 100 Years
Start Date 2024-01-08
Completion 2027-08
Interventions
No intervention other than obtaining biopsiesIndocyanine green (ICG)

Brief Summary

100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1. The aim is to examine and quantify the cardiovascular and lymphatic system in women with TS. The investigators will study a possible causal mechanism between the known pathologic phenotype and alterations in these systems to understand, prevent or treat the life-threatening complications in TS.

Eligibility Criteria

Inclusion Criteria: * Turner Syndrome Exclusion Criteria: * pregnancy * contraindications for MRI

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