State RI
Clinical Trials in Rhode Island
Rhode Island is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Rhode Island and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 81 actively recruiting studies with Rhode Island sites out of 81 registered in total. The busiest research areas in Rhode Island are Alcohol Use Disorder, Obesity, Acute Stress Disorder. Leading sponsors running trials in the state include National Cancer Institute (NCI), AstraZeneca, Rhode Island Hospital. By stage, Rhode Island trials break down as Phase 1 (10), Phase 2 (21), Phase 3 (24), Phase 4 (1).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Rhode Island
Frequently Asked Questions — Clinical Trials in Rhode Island
How many clinical trials are currently recruiting in Rhode Island?
ClinicalMetric currently tracks 81 actively recruiting clinical trials with at least one location in Rhode Island. The total number of registered studies—including active but not currently enrolling trials—is 81. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Rhode Island?
Rhode Island hosts clinical trials across a broad range of medical conditions, including Alcohol Use Disorder, Obesity, Acute Stress Disorder, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Rhode Island serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Rhode Island?
To join a clinical trial in Rhode Island, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Rhode Island maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Rhode Island
NCT07118839 Phase 2, Phase 3
Recruiting
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder
Condition
Post Traumatic Stress Disorder
Enrollment
80 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT04852887 Phase 3
Recruiting
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, O...
Condition
Stage I Breast Cancer
Enrollment
1,670 pts
Location
United States, Canada, Hong Kong
Sponsor
NRG Oncology
NCT05968326 Phase 2
Recruiting
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizu...
Condition
Adenocarcinoma, Pancreatic Ductal
Enrollment
260 pts
Location
United States, Belgium, Canada
Sponsor
Genentech, Inc.
NCT04609046 Phase 1
Recruiting
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Pr...
Condition
Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
Enrollment
47 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT06994923 N/A
Recruiting
Weight Management Intervention in College: A Pilot
Condition
Obesity and Overweight
Enrollment
60 pts
Location
United States
Sponsor
The Miriam Hospital
NCT06319027 Phase 2
Recruiting
Identifying Findings on Brain Scans That Could Help Make Better Predictions Abou...
Condition
Glioblastoma, IDH-Wildtype
Enrollment
100 pts
Location
United States
Sponsor
ECOG-ACRIN Cancer Research Gro
NCT06849869 N/A
Recruiting
Collaborative Care Model for Perinatal Wellness Support Services - Population-Le...
Condition
Perinatal Mental Health
Enrollment
14,820 pts
Location
United States
Sponsor
Women and Infants Hospital of
NCT02523014 Phase 2
Recruiting
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating ...
Condition
Intracranial Meningioma
Enrollment
124 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT00063063 N/A
Recruiting
Generic Database of Very Low Birth Weight Infants
Condition
Infant, Newborn
Enrollment
80,000 pts
Location
United States
Sponsor
NICHD Neonatal Research Networ
NCT00358943 N/A
Recruiting
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Preg...
Condition
Gaucher Disease
Enrollment
12,000 pts
Location
United States, Argentina, Australia
Sponsor
Genzyme, a Sanofi Company
NCT07197476 N/A
Recruiting
Adolescent Stress and Substance Intervention Subsequent to Trauma
Condition
PTSD
Enrollment
92 pts
Location
United States
Sponsor
Rhode Island Hospital
NCT05918861 Phase 3
Recruiting
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Rece...
Condition
Acute Coronary Syndrome
Enrollment
2,000 pts
Location
United States, Canada, Puerto Rico
Sponsor
DalCor Pharmaceuticals
NCT04402788 Phase 2, Phase 3
Recruiting
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment ...
Condition
Extensive Stage Lung Small Cell Carcinoma
Enrollment
138 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT04322318 Phase 2
Recruiting
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and R...
Condition
Anaplastic Kidney Wilms Tumor
Enrollment
256 pts
Location
United States, Australia, Canada
Sponsor
Children's Oncology Group
NCT06605118 Phase 3
Recruiting
Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
Condition
Obstetrical Complications
Enrollment
8,000 pts
Location
United States
Sponsor
The George Washington Universi
NCT07144631 N/A
Recruiting
Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome
Condition
Restless Leg Disorder
Enrollment
15 pts
Location
United States
Sponsor
Rhode Island Hospital
NCT06439953 N/A
Recruiting
Irrisept Solution for Instrumented Spine Surgery
Condition
Post-Op Complication
Enrollment
200 pts
Location
United States
Sponsor
Rhode Island Hospital
NCT06432465 N/A
Recruiting
tDCS to Decrease Opioid Relapse (UH3)
Condition
Opioid Use Disorder
Enrollment
100 pts
Location
United States
Sponsor
Butler Hospital
NCT00231400 N/A
Recruiting
Pompe Disease Registry Protocol
Condition
Glycogen Storage Disease Type II
Enrollment
2,000 pts
Location
United States, Argentina, Australia
Sponsor
Genzyme, a Sanofi Company
NCT06330493 N/A
Recruiting
AcoArt Litos PCB Below-the-knee Global Trial
Condition
Chronic Limb-Threatening Ischemia
Enrollment
288 pts
Location
United States, Austria, Belgium
Sponsor
Acotec Scientific Co., Ltd
NCT06435429 Phase 3
Recruiting
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in...
Condition
Metastatic HER2-positive Breast Cancer
Enrollment
550 pts
Location
United States, Australia, Austria
Sponsor
Jazz Pharmaceuticals
NCT05836324 Phase 1
Recruiting
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Met...
Condition
Solid Tumors
Enrollment
408 pts
Location
United States, Denmark, France
Sponsor
Incyte Corporation
NCT06058377 Phase 3
Recruiting
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy T...
Condition
Anatomic Stage II Breast Cancer AJCC v8
Enrollment
3,680 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT06750185 Phase 1
Recruiting
Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for A...
Condition
Advanced Solid Tumor
Enrollment
39 pts
Location
United States, Australia
Sponsor
BioNTech SE
NCT04267848 Phase 3
Recruiting
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemoth...
Condition
Lung Non-Small Cell Carcinoma
Enrollment
1,210 pts
Location
United States, Guam
Sponsor
National Cancer Institute (NCI
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology