NCT05389930 Cannabis' Impact on Alcohol Consumption
| NCT ID | NCT05389930 |
| Status | Recruiting |
| Phase | Phase 2 |
| Sponsor | Brown University |
| Condition | Alcohol Drinking |
| Study Type | INTERVENTIONAL |
| Enrollment | 350 participants |
| Start Date | 2023-03-16 |
| Primary Completion | 2027-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.
This trial targets 350 participants in total. It began in 2023-03-16 with a primary completion date of 2027-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.
Eligibility Criteria
Inclusion Criteria: * Age 21 to 50 * English-speaking * cannabis smoking in past two months * heavy drinking in past two months * in good physical health and weighing \< 250 lbs * zero breath alcohol at each visit Exclusion Criteria: * positive pregnancy test * nursing * positive urine toxicology screen for drugs other than cannabis * interest to quit or receive treatment for cannabis or alcohol use
Contact & Investigator
Jane Metrik, PhD
PRINCIPAL INVESTIGATOR
Brown University
Frequently Asked Questions
Who can join the NCT05389930 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 50 Years, studying Alcohol Drinking. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT05389930 trial and what does that mean for participants?
Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.
Is NCT05389930 currently recruiting?
Yes, NCT05389930 is actively recruiting participants. Contact the research team at Jane_Metrik@brown.edu for enrollment information.
Where is the NCT05389930 trial being conducted?
This trial is being conducted at Providence, United States.
Who is sponsoring the NCT05389930 clinical trial?
NCT05389930 is sponsored by Brown University. The principal investigator is Jane Metrik, PhD at Brown University. The trial plans to enroll 350 participants.