State ME
Clinical Trials in Maine
Maine is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Maine and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 39 actively recruiting studies with Maine sites out of 39 registered in total. The busiest research areas in Maine are Acute Myeloid Leukemia, Breast Neoplasms, Endometrial Cancer. Leading sponsors running trials in the state include National Cancer Institute (NCI), Merck Sharp & Dohme LLC, Children's Oncology Group. By stage, Maine trials break down as Phase 1 (2), Phase 2 (8), Phase 3 (17), Phase 4 (2).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Maine
Acute Myeloid Leukemia (2)Breast Neoplasms (2)Endometrial Cancer (2)Lung Non-Small Cell Carcinoma (2)Breast Cancer (2)Neovascular Age-related Macular Degeneration (1)Renal Cell Carcinoma (1)Non-Traumatic Subarachnoid Hemorrhage (1)Ganglioneuroblastoma, Nodular (1)Neuroblastoma (1)Advanced Endometrial Carcinoma (1)Recurrent Endometrial Carcinoma (1)
Frequently Asked Questions — Clinical Trials in Maine
How many clinical trials are currently recruiting in Maine?
ClinicalMetric currently tracks 39 actively recruiting clinical trials with at least one location in Maine. The total number of registered studies—including active but not currently enrolling trials—is 39. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Maine?
Maine hosts clinical trials across a broad range of medical conditions, including Acute Myeloid Leukemia, Breast Neoplasms, Endometrial Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Maine serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Maine?
To join a clinical trial in Maine, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Maine maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Maine
NCT04853251 Phase 4
Recruiting
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age...
Condition
Neovascular Age-related Macular Degeneration
Enrollment
188 pts
Location
United States
Sponsor
Genentech, Inc.
NCT07227402 Phase 3
Recruiting
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney...
Condition
Renal Cell Carcinoma
Enrollment
904 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT06569212 Phase 4
Recruiting
Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Sub...
Condition
Non-Traumatic Subarachnoid Hemorrhage
Enrollment
20 pts
Location
United States
Sponsor
Madeleine Puissant
NCT06172296 Phase 3
Recruiting
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Tre...
Condition
Ganglioneuroblastoma, Nodular
Enrollment
478 pts
Location
United States, Australia, Canada
Sponsor
National Cancer Institute (NCI
NCT06672146 Phase 2
Recruiting
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia ...
Condition
Acute Myeloid Leukemia
Enrollment
93 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT07173751 Phase 3
Recruiting
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-N...
Condition
Breast Neoplasms
Enrollment
558 pts
Location
United States, Australia, Belgium
Sponsor
BioNTech SE
NCT04486352 Phase 1, Phase 2
Recruiting
A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial...
Condition
Endometrial Cancer
Enrollment
148 pts
Location
United States
Sponsor
Alliance Foundation Trials, LL
NCT07198074 Phase 3
Recruiting
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Ca...
Condition
Advanced Endometrial Carcinoma
Enrollment
255 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT05564390 Phase 2
Recruiting
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatmen...
Condition
Acute Myeloid Leukemia
Enrollment
2,000 pts
Location
United States, Canada, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT05774951 Phase 3
Recruiting
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years ...
Condition
Breast Cancer, Early Breast Cancer
Enrollment
4,300 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT05848713 Phase 3
Recruiting
AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquire...
Condition
Community-acquired Pneumonia
Enrollment
4,000 pts
Location
United States, Brazil, Canada
Sponsor
University of Manitoba
NCT06952504 Phase 3
Recruiting
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrol...
Condition
Endometrial Cancer
Enrollment
1,123 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT04251052 N/A
Recruiting
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations t...
Condition
Ovarian Carcinoma
Enrollment
1,956 pts
Location
United States, Canada, South Korea
Sponsor
NRG Oncology
NCT05235165 Phase 3
Recruiting
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients ...
Condition
Metastatic Malignant Neoplasm in the Lung
Enrollment
62 pts
Location
United States, Australia, Canada
Sponsor
Children's Oncology Group
NCT02981628 Phase 2
Recruiting
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma...
Condition
Recurrent B Acute Lymphoblastic Leukemia
Enrollment
80 pts
Location
United States, Puerto Rico
Sponsor
Children's Oncology Group
NCT06226272 N/A
Recruiting
Clinical Outcome Measure at Stryker Spine
Condition
Degenerative Disc Disease
Enrollment
5,222 pts
Location
United States
Sponsor
VB Spine, LLC
NCT06087029 N/A
Recruiting
IMPRoving Outcomes in Vascular DisEase - Aortic Dissection
Condition
Type B Aortic Dissection
Enrollment
1,100 pts
Location
United States, Canada
Sponsor
Duke University
NCT06418204 N/A
Recruiting
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients T...
Condition
Breast Carcinoma
Enrollment
2,000 pts
Location
United States, Puerto Rico
Sponsor
Wake Forest University Health
NCT07085767 Phase 3
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/...
Condition
Breast Cancer
Enrollment
1,000 pts
Location
United States, Australia, Austria
Sponsor
Olema Pharmaceuticals, Inc.
NCT06312137 Phase 3
Recruiting
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzum...
Condition
Non Small Cell Lung Cancer
Enrollment
780 pts
Location
United States, Argentina, Australia
Sponsor
Merck Sharp & Dohme LLC
NCT04968834 N/A
Recruiting
Genomically Profiling, Collecting, Archiving and Distributing Hematologic Malign...
Condition
Leukemia
Enrollment
300 pts
Location
United States
Sponsor
Dana-Farber Cancer Institute
NCT07195734 Phase 2
Recruiting
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery...
Condition
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Enrollment
180 pts
Location
United States
Sponsor
National Cancer Institute (NCI
NCT07213804 Phase 3
Recruiting
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum...
Condition
Ovarian Neoplasms
Enrollment
1,630 pts
Location
United States, Australia, Austria
Sponsor
Eli Lilly and Company
NCT00196742 N/A
Recruiting
Fabry Disease Registry & Pregnancy Sub-registry
Condition
Fabry Disease
Enrollment
9,000 pts
Location
United States, Argentina, Australia
Sponsor
Genzyme, a Sanofi Company
NCT04852887 Phase 3
Recruiting
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, O...
Condition
Stage I Breast Cancer
Enrollment
1,670 pts
Location
United States, Canada, Hong Kong
Sponsor
NRG Oncology
Page 1 of 2 — 39 trials total
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology