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Clinical Trials in Maryland

Maryland is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Maryland and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 402 actively recruiting studies with Maryland sites out of 402 registered in total. The busiest research areas in Maryland are Stroke, Obesity, Prostate Cancer. Leading sponsors running trials in the state include Johns Hopkins University, National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID). By stage, Maryland trials break down as Phase 1 (64), Phase 2 (92), Phase 3 (83), Phase 4 (5).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
402
Recruiting Now
402
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Top Conditions in Maryland
Stroke (8)Obesity (5)Prostate Cancer (5)Schizophrenia (5)Acute Myeloid Leukemia (5)Healthy Volunteers (5)Cervical Cancer (4)Heart Failure (4)Carcinoma, Non-Small-Cell Lung (4)Malignant Solid Neoplasm (3)Retinitis Pigmentosa (3)B Acute Lymphoblastic Leukemia (3)

Frequently Asked Questions — Clinical Trials in Maryland

How many clinical trials are currently recruiting in Maryland?
ClinicalMetric currently tracks 402 actively recruiting clinical trials with at least one location in Maryland. The total number of registered studies—including active but not currently enrolling trials—is 402. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Maryland?
Maryland hosts clinical trials across a broad range of medical conditions, including Stroke, Obesity, Prostate Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Maryland serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Maryland?
To join a clinical trial in Maryland, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Maryland maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Maryland

NCT05589714 N/A
Recruiting
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystr...
Condition
Inherited Retinal Degeneration
Enrollment
1,500 pts
Location
United States, Australia, Belgium
Sponsor
Jaeb Center for Health Researc
View Trial →
NCT07247058 Phase 4
Recruiting
Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)
Condition
Mild Autonomous Cortisol Secretion (MACS)
Enrollment
10 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT05041387 N/A
Recruiting
Data Collection of Standard Care of Patients in the EMG Section
Condition
Neuropathy
Enrollment
200 pts
Location
United States
Sponsor
National Institute of Neurolog
View Trial →
NCT05934487 N/A
Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Condition
Heart Failure NYHA Class II
Enrollment
1,750 pts
Location
United States, Belgium, Ireland
Sponsor
Endotronix, Inc.
View Trial →
NCT06847321 Phase 2
Recruiting
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Condition
Alzheimer Disease
Enrollment
300 pts
Location
United States
Sponsor
Lighthouse Pharmaceuticals, In
View Trial →
NCT05967299 Phase 1
Recruiting
Study of Intravenous ZMA001 in Healthy Subjects
Condition
Pulmonary Arterial Hypertension PAH
Enrollment
96 pts
Location
United States
Sponsor
National Heart, Lung, and Bloo
View Trial →
NCT05443906 N/A
Recruiting
Home Exercise for Individuals with Neurodegenerative Disease
Condition
Neurodegenerative Diseases
Enrollment
30 pts
Location
United States
Sponsor
Hugo W. Moser Research Institu
View Trial →
NCT06589804 Phase 3
Recruiting
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatme...
Condition
Metastatic Head and Neck Squamous Cell Carcinoma
Enrollment
158 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT03142152 N/A
Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failur...
Condition
Functional Mitral Regurgitation
Enrollment
300 pts
Location
United States, Canada, France
Sponsor
Cardiac Dimensions, Inc.
View Trial →
NCT04777357 Phase 3
Recruiting
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Carip...
Condition
Depression
Enrollment
380 pts
Location
United States, Puerto Rico, Russia
Sponsor
AbbVie
View Trial →
NCT06658730 N/A
Recruiting
Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With A...
Condition
Vascular Disease
Enrollment
1,500 pts
Location
United States, Denmark, France
Sponsor
W.L.Gore & Associates
View Trial →
NCT00091871 N/A
Recruiting
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Mar...
Condition
Eosinophilia
Enrollment
50 pts
Location
United States
Sponsor
National Institute of Allergy
View Trial →
NCT06846671 Phase 3
Recruiting
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Partici...
Condition
CLL
Enrollment
250 pts
Location
United States, Argentina, Australia
Sponsor
BeOne Medicines
View Trial →
NCT06134232 Phase 2
Recruiting
Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + ...
Condition
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Enrollment
400 pts
Location
United States
Sponsor
Dendreon
View Trial →
NCT06556563 Phase 3
Recruiting
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pe...
Condition
Glioblastoma
Enrollment
741 pts
Location
United States, Canada, Czechia
Sponsor
NovoCure GmbH
View Trial →
NCT06153459 N/A
Recruiting
Cord Clamping Among Neonates With Congenital Heart Disease
Condition
Congenital Heart Disease (CHD)
Enrollment
500 pts
Location
United States, Canada
Sponsor
Carl Backes, MD
View Trial →
NCT03206060 Phase 2
Recruiting
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paragangl...
Condition
Pheochromocytoma
Enrollment
130 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT02000089 Phase 3
Recruiting
The Cancer of the Pancreas Screening-5 CAPS5)Study
Condition
Pancreas Cancer
Enrollment
9,000 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT06846320 Phase 2
Recruiting
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932...
Condition
Generalized Anxiety Disorder (GAD)
Enrollment
315 pts
Location
United States, Puerto Rico
Sponsor
AbbVie
View Trial →
NCT06032923 Phase 1, Phase 2
Recruiting
Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting Wi...
Condition
Systemic Lupus Erythematosus (Sle)
Enrollment
78 pts
Location
United States
Sponsor
National Heart, Lung, and Bloo
View Trial →
NCT07213804 Phase 3
Recruiting
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum...
Condition
Ovarian Neoplasms
Enrollment
1,630 pts
Location
United States, Australia, Austria
Sponsor
Eli Lilly and Company
View Trial →
NCT04449549 Phase 2
Recruiting
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in ...
Condition
Neoplasms
Enrollment
82 pts
Location
United States
Sponsor
National Cancer Institute (NCI
View Trial →
NCT05845047 N/A
Recruiting
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE...
Condition
Aphasia
Enrollment
70 pts
Location
United States
Sponsor
Johns Hopkins University
View Trial →
NCT07111078 Phase 1
Recruiting
Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and W...
Condition
Influenza Prevention
Enrollment
56 pts
Location
United States
Sponsor
National Institute of Allergy
View Trial →
NCT07593391 Phase 3
Recruiting
An Open-label Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid S...
Condition
Phelan-McDermid Syndrome
Enrollment
180 pts
Location
United States
Sponsor
Neuren Pharmaceuticals Limited
View Trial →
Page 6 of 17 — 402 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology