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Clinical Trials in Illinois

Illinois is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Illinois and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.

Right now ClinicalMetric tracks 406 actively recruiting studies with Illinois sites out of 406 registered in total. The busiest research areas in Illinois are Ovarian Cancer, Breast Cancer, Prostate Cancer. Leading sponsors running trials in the state include University of Chicago, Northwestern University, National Cancer Institute (NCI). By stage, Illinois trials break down as Phase 1 (66), Phase 2 (130), Phase 3 (103), Phase 4 (13).

All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.

Total Trials
406
Recruiting Now
406
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Top Conditions in Illinois
Ovarian Cancer (8)Breast Cancer (7)Prostate Cancer (5)Heart Failure (5)Acute Myeloid Leukemia (5)Prostate Adenocarcinoma (5)Endometrial Cancer (5)Obesity (5)Solid Tumor (4)Colorectal Cancer (4)Metastatic Breast Cancer (4)Pancreatic Cancer (3)

Frequently Asked Questions — Clinical Trials in Illinois

How many clinical trials are currently recruiting in Illinois?
ClinicalMetric currently tracks 406 actively recruiting clinical trials with at least one location in Illinois. The total number of registered studies—including active but not currently enrolling trials—is 406. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Illinois?
Illinois hosts clinical trials across a broad range of medical conditions, including Ovarian Cancer, Breast Cancer, Prostate Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Illinois serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Illinois?
To join a clinical trial in Illinois, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Illinois maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.

Recruiting Trials in Illinois

NCT07365241 Phase 3
Recruiting
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous...
Condition
Small Cell Lung Cancer
Enrollment
531 pts
Location
United States, Austria, Belgium
Sponsor
AbbVie
View Trial →
NCT07610395 Phase 2
Recruiting
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Pla...
Condition
Rhinovirus Infection
Enrollment
180 pts
Location
United States, United Kingdom
Sponsor
Altesa Biosciences, Inc.
View Trial →
NCT03866382 Phase 2
Recruiting
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) ...
Condition
Bladder Adenocarcinoma
Enrollment
314 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
View Trial →
NCT05919680 Phase 2
Recruiting
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease...
Condition
Intestinal Failure Associated Liver Disease
Enrollment
36 pts
Location
United States
Sponsor
NorthSea Therapeutics B.V.
View Trial →
NCT03739814 Phase 2
Recruiting
Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Pat...
Condition
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Enrollment
84 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
View Trial →
NCT04786262 Phase 3
Recruiting
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants ...
Condition
Diabetes Mellitus, Type 1
Enrollment
57 pts
Location
United States, Canada, France
Sponsor
Vertex Pharmaceuticals Incorpo
View Trial →
Page 17 of 17 — 406 trials total
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology