State AL
Clinical Trials in Alabama
Alabama is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Alabama and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 192 actively recruiting studies with Alabama sites out of 192 registered in total. The busiest research areas in Alabama are Multiple Myeloma, Sickle Cell Disease, Obesity. Leading sponsors running trials in the state include University of Alabama at Birmingham, AstraZeneca, Novartis Pharmaceuticals. By stage, Alabama trials break down as Phase 1 (29), Phase 2 (58), Phase 3 (53), Phase 4 (11).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Alabama
Frequently Asked Questions — Clinical Trials in Alabama
How many clinical trials are currently recruiting in Alabama?
ClinicalMetric currently tracks 192 actively recruiting clinical trials with at least one location in Alabama. The total number of registered studies—including active but not currently enrolling trials—is 192. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Alabama?
Alabama hosts clinical trials across a broad range of medical conditions, including Multiple Myeloma, Sickle Cell Disease, Obesity, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Alabama serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Alabama?
To join a clinical trial in Alabama, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Alabama maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Alabama
NCT07230288 Phase 2
Recruiting
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adu...
Condition
Idiopathic Pulmonary Fibrosis
Enrollment
165 pts
Location
United States, Australia, Bulgaria
Sponsor
AbbVie
NCT06655246 Phase 1
Recruiting
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gas...
Condition
Gastrointestinal Stromal Tumor (GIST)
Enrollment
157 pts
Location
United States
Sponsor
Kura Oncology, Inc.
NCT06505603 N/A
Recruiting
PiMZ Longitudinal Cohort (PiMZ Logic)
Condition
Alpha 1-Antitrypsin Deficiency
Enrollment
80 pts
Location
United States
Sponsor
Columbia University
NCT05677490 Phase 3
Recruiting
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanc...
Condition
Advanced Esophageal Adenocarcinoma
Enrollment
382 pts
Location
United States, Puerto Rico
Sponsor
Alliance for Clinical Trials i
NCT06326476 EARLY_Phase 1
Recruiting
Evaluate the Safety and Efficacy of Subcutaneous Siplizumab in the Treatment of ...
Condition
Hidradenitis Suppurativa
Enrollment
12 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05533775 Phase 1, Phase 2
Recruiting
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy i...
Condition
Mature B-Cell Non-Hodgkin Lymphoma
Enrollment
65 pts
Location
United States, Australia, Brazil
Sponsor
Hoffmann-La Roche
NCT04239573 N/A
Recruiting
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Assoc...
Condition
Pancreatic Neoplasm
Enrollment
770 pts
Location
United States, Canada, Puerto Rico
Sponsor
ECOG-ACRIN Cancer Research Gro
NCT06726161 Phase 1, Phase 2
Recruiting
Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Id...
Condition
Hepatocellular Carcinoma (HCC)
Enrollment
590 pts
Location
United States
Sponsor
RayzeBio, Inc.
NCT06296394 N/A
Recruiting
Health Outcomes of Parents With Cystic Fibrosis-Aim 2
Condition
Cystic Fibrosis
Enrollment
146 pts
Location
United States
Sponsor
University of Pittsburgh
NCT05763251 N/A
Recruiting
Comparison of Uncomplicated Candidemia Therapy Duration in Children
Condition
Invasive Candidiasis
Enrollment
420 pts
Location
United States, Australia
Sponsor
Arkansas Children's Hospital R
NCT04202341 N/A
Recruiting
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion...
Condition
Generalized Myasthenia Gravis
Enrollment
500 pts
Location
United States, Austria, Canada
Sponsor
Alexion Pharmaceuticals, Inc.
NCT06712654 Phase 2
Recruiting
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in...
Condition
Hyperphosphatemia
Enrollment
168 pts
Location
United States, China
Sponsor
R1 Therapeutics
NCT07223086 N/A
Recruiting
Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity
Condition
Concussion, Mild
Enrollment
60 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT07089576 N/A
Recruiting
Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA
Condition
Aortic Arch Aneurysm
Enrollment
132 pts
Location
United States
Sponsor
Artivion Inc.
NCT07218887 Phase 1, Phase 2
Recruiting
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
Condition
BAG3 Mutation Associated Dilated Cardiomyopathy
Enrollment
6 pts
Location
United States, Italy, Spain
Sponsor
Alexion Pharmaceuticals, Inc.
NCT07246863 Phase 2
Recruiting
Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Tre...
Condition
Metastatic Non-Squamous Non-Small Cell Lung Cancer
Enrollment
131 pts
Location
United States, Germany, Italy
Sponsor
CatalYm GmbH
NCT06998043 Phase 2
Recruiting
Study With Phage for CF Subjects With Pseudomonas Lung Infection
Condition
Chronic Pseudomonas Aeruginosa Infection
Enrollment
63 pts
Location
United States
Sponsor
BiomX Ltd
NCT04362644 Phase 1
Recruiting
Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosi...
Condition
Idiopathic Pulmonary Fibrosis
Enrollment
10 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT06317649 Phase 2
Recruiting
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute M...
Condition
Acute Myeloid Leukemia
Enrollment
147 pts
Location
United States, Puerto Rico
Sponsor
National Cancer Institute (NCI
NCT05677971 Phase 3
Recruiting
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People ...
Condition
Alpha1-Antitrypsin Deficiency
Enrollment
160 pts
Location
United States, Australia, Austria
Sponsor
Takeda
NCT07025421 N/A
Recruiting
The ARISE Study - Use of Vertical Positioning
Condition
Acute Respiratory Distress Syndrome
Enrollment
40 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT06237452 Phase 3
Recruiting
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Condition
Clostridium Difficile
Enrollment
852 pts
Location
United States, Australia, Belgium
Sponsor
Vedanta Biosciences, Inc.
NCT05606432 N/A
Recruiting
Cardiometabolic Health Intervention Using Movement-to-Music Exercise
Condition
Cardiometabolic Risk Factors in Adult Wheelchair Users
Enrollment
132 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT07284784 Phase 2, Phase 3
Recruiting
A Study of Buntanetap in Participants With PD
Condition
Parkinson's Disease (PD)
Enrollment
500 pts
Location
United States
Sponsor
Annovis Bio Inc.
NCT05676476 N/A
Recruiting
The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensi...
Condition
Preeclampsia
Enrollment
132 pts
Location
United States
Sponsor
University of Alabama at Birmi
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology