State AL
Clinical Trials in Alabama
Alabama is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Alabama and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 158 actively recruiting studies with Alabama sites out of 158 registered in total. The busiest research areas in Alabama are Obesity, Ovarian Cancer, Prostate Cancer. Leading sponsors running trials in the state include University of Alabama at Birmingham, AstraZeneca, Pfizer. By stage, Alabama trials break down as Phase 1 (20), Phase 2 (43), Phase 3 (47), Phase 4 (8).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Alabama
Frequently Asked Questions — Clinical Trials in Alabama
How many clinical trials are currently recruiting in Alabama?
ClinicalMetric currently tracks 158 actively recruiting clinical trials with at least one location in Alabama. The total number of registered studies—including active but not currently enrolling trials—is 158. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Alabama?
Alabama hosts clinical trials across a broad range of medical conditions, including Obesity, Ovarian Cancer, Prostate Cancer, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Alabama serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Alabama?
To join a clinical trial in Alabama, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Alabama maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Alabama
NCT05911568 N/A
Recruiting
Treatment With Endovascular Intervention for STroke Patients With Existing Disab...
Condition
Stroke
Enrollment
1,060 pts
Location
United States
Sponsor
University of Cincinnati
NCT06147258 N/A
Recruiting
The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in A...
Condition
Spinal Cord Injuries
Enrollment
60 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT06976268 Phase 2, Phase 3
Recruiting
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment...
Condition
Parkinson Disease
Enrollment
550 pts
Location
United States
Sponsor
Biohaven Therapeutics Ltd.
NCT07593391 Phase 3
Recruiting
An Open-label Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid S...
Condition
Phelan-McDermid Syndrome
Enrollment
180 pts
Location
United States
Sponsor
Neuren Pharmaceuticals Limited
NCT03850574 Phase 1, Phase 2
Recruiting
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharma...
Condition
Leukemia, Myeloid, Acute
Enrollment
240 pts
Location
United States, Australia, Germany
Sponsor
Aptose Biosciences Inc.
NCT07219420 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants...
Condition
Palmoplantar Pustulosis
Enrollment
320 pts
Location
United States, Canada, China
Sponsor
UCB Biopharma SRL
NCT07227246 Phase 3
Recruiting
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2
Condition
Intracerebral Hemorrhage
Enrollment
350 pts
Location
United States, Canada, Germany
Sponsor
Joseph Broderick, MD
NCT04363684 N/A
Recruiting
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Condition
Frontotemporal Lobar Degeneration (FTLD)
Enrollment
2,100 pts
Location
United States, Canada
Sponsor
Mayo Clinic
NCT06562543 Phase 4
Recruiting
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populati...
Condition
Colorectal Cancer
Enrollment
78 pts
Location
United States, Puerto Rico
Sponsor
Takeda
NCT04781140 Phase 4
Recruiting
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Chi...
Condition
Attention-Deficit/Hyperactivity Disorder
Enrollment
286 pts
Location
United States
Sponsor
Supernus Pharmaceuticals, Inc.
NCT02397668 N/A
Recruiting
CorMatrix Cor TRICUSPID ECM Valve Replacement Study
Condition
Tricuspid Valve Disease
Enrollment
78 pts
Location
United States
Sponsor
Corvivo Cardiovascular, Inc.
NCT05868226 Phase 1, Phase 2
Recruiting
PRE-ISPY Phase I/II Oncology Platform Program
Condition
HER2-positive Breast Cancer
Enrollment
280 pts
Location
United States
Sponsor
QuantumLeap Healthcare Collabo
NCT07502443 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolep...
Condition
Narcolepsy Type 2
Enrollment
176 pts
Location
United States, Australia, Belgium
Sponsor
Alkermes, Inc.
NCT05864274 N/A
Recruiting
Improve Cancer-related Cognitive Impairment
Condition
Gynecologic Cancer
Enrollment
64 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT06654193 Phase 1, Phase 2
Recruiting
Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury
Condition
Acute Kidney Injury
Enrollment
70 pts
Location
United States
Sponsor
Hope Biosciences LLC
NCT06964087 Phase 2
Recruiting
Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Me...
Condition
Type I Diabetes
Enrollment
72 pts
Location
United States
Sponsor
Op-T LLC
NCT07725315 N/A
Recruiting
Investigating the Increased Risk of Falls in Individuals With Parkinson's Diseas...
Condition
Deep Brain Stimulation
Enrollment
20 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05237258 N/A
Recruiting
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute...
Condition
Relapsed Adult AML
Enrollment
2,300 pts
Location
United States
Sponsor
Massachusetts General Hospital
NCT07226661 Phase 2
Recruiting
Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder
Condition
Major Depressive Disorder (MDD)
Enrollment
230 pts
Location
United States
Sponsor
Supernus Pharmaceuticals, Inc.
NCT06701903 Phase 2
Recruiting
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety ...
Condition
Generalized Anxiety Disorder
Enrollment
570 pts
Location
United States, Bulgaria, Poland
Sponsor
Intra-Cellular Therapies, Inc.
NCT07276997 Phase 2
Recruiting
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcapr...
Condition
Major Depressive Disorder
Enrollment
195 pts
Location
United States
Sponsor
AbbVie
NCT07037459 Phase 3
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejecti...
Condition
Heart Failure With Preserved Ejection Fraction
Enrollment
5,056 pts
Location
United States, Argentina, Australia
Sponsor
Amgen
NCT05338697 N/A
Recruiting
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future...
Condition
Stroke
Enrollment
657 pts
Location
United States
Sponsor
Yale University
NCT07441694 Phase 1
Recruiting
Study of INCA036978 in Participants With Myeloproliferative Neoplasms
Condition
Myeloproliferative Neoplasms
Enrollment
218 pts
Location
United States, Australia, Belgium
Sponsor
Incyte Corporation
NCT05431088 Phase 2, Phase 3
Recruiting
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
Condition
Sickle Cell Disease
Enrollment
389 pts
Location
United States, Brazil, India
Sponsor
Pfizer
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology