State AL
Clinical Trials in Alabama
Alabama is home to a significant concentration of clinical research activity, with academic medical centers, community hospitals, and specialized research clinics serving as active trial sites across a broad range of medical conditions. The studies listed here have at least one enrolled site in Alabama and represent Phase 1 through Phase 4 research sponsored by NIH, pharmaceutical companies, device manufacturers, and independent investigators.
Right now ClinicalMetric tracks 192 actively recruiting studies with Alabama sites out of 192 registered in total. The busiest research areas in Alabama are Multiple Myeloma, Sickle Cell Disease, Obesity. Leading sponsors running trials in the state include University of Alabama at Birmingham, AstraZeneca, Novartis Pharmaceuticals. By stage, Alabama trials break down as Phase 1 (29), Phase 2 (58), Phase 3 (53), Phase 4 (11).
All trial data is sourced directly from ClinicalTrials.gov and updated daily. Recruiting status, eligibility criteria, enrollment targets, and contact information are included for each study. Patients and caregivers should review the full eligibility criteria on each trial listing — or consult their treating physician — before contacting a study site.
Top Conditions in Alabama
Frequently Asked Questions — Clinical Trials in Alabama
How many clinical trials are currently recruiting in Alabama?
ClinicalMetric currently tracks 192 actively recruiting clinical trials with at least one location in Alabama. The total number of registered studies—including active but not currently enrolling trials—is 192. Trial availability is updated daily from ClinicalTrials.gov, and new studies open enrollment regularly throughout the year.
What types of clinical trials are available in Alabama?
Alabama hosts clinical trials across a broad range of medical conditions, including Multiple Myeloma, Sickle Cell Disease, Obesity, and many others. Trials range from Phase 1 early-safety studies to Phase 4 post-approval surveillance, as well as observational and behavioral research. Academic medical centers, community hospitals, and specialized research clinics throughout Alabama serve as trial sites for studies sponsored by NIH, pharmaceutical companies, and independent investigators.
How do I join a clinical trial near me in Alabama?
To join a clinical trial in Alabama, browse the recruiting studies listed on this page, review the eligibility criteria for each trial, and contact the study site directly. Your primary care physician or specialist can also refer you to clinical trials relevant to your diagnosis. Many academic medical centers in Alabama maintain dedicated clinical trials offices that can match you with appropriate studies based on your medical profile and diagnosis.
Recruiting Trials in Alabama
NCT06969755 Phase 4
Recruiting
Biomarkers to Enhance Early Schizophrenia Treatment
Condition
Schizophenia Disorder
Enrollment
180 pts
Location
United States, Canada
Sponsor
Northwell Health
NCT07652658 Phase 2
Recruiting
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
Condition
Idiopathic Pulmonary Fibrosis (IPF)
Enrollment
359 pts
Location
United States, Argentina, Australia
Sponsor
AstraZeneca
NCT04910685 Phase 2, Phase 3
Recruiting
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Pati...
Condition
Indolent Systemic Mastocytosis
Enrollment
534 pts
Location
United States, Argentina, Australia
Sponsor
Blueprint Medicines Corporatio
NCT06581328 Phase 4
Recruiting
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in t...
Condition
Ulcerative Colitis
Enrollment
400 pts
Location
United States
Sponsor
Takeda
NCT04920136 N/A
Recruiting
Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination ...
Condition
Gingival Recession
Enrollment
20 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05232916 Phase 3
Recruiting
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (...
Condition
Breast Cancer
Enrollment
2,250 pts
Location
United States, Belgium, France
Sponsor
Greenwich LifeSciences, Inc.
NCT05618353 Phase 4
Recruiting
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
Condition
Coronary Artery Disease
Enrollment
700 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT07326709 Phase 3
Recruiting
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Part...
Condition
Huntington Disease
Enrollment
770 pts
Location
United States, Argentina, Australia
Sponsor
Novartis Pharmaceuticals
NCT05966493 Phase 2
Recruiting
A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic G...
Condition
Persistent Corneal Epithelial Defect
Enrollment
84 pts
Location
United States, Germany, Italy
Sponsor
Glaukos Corporation
NCT05006716 Phase 1, Phase 2
Recruiting
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participant...
Condition
B-cell Malignancy
Enrollment
645 pts
Location
United States, Australia, Brazil
Sponsor
BeOne Medicines
NCT07497087 Phase 3
Recruiting
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
Condition
Systemic Sclerosis
Enrollment
448 pts
Location
United States, Argentina, Australia
Sponsor
Boehringer Ingelheim
NCT02523014 Phase 2
Recruiting
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating ...
Condition
Intracranial Meningioma
Enrollment
124 pts
Location
United States
Sponsor
Alliance for Clinical Trials i
NCT03150693 Phase 3
Recruiting
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With N...
Condition
B Acute Lymphoblastic Leukemia
Enrollment
303 pts
Location
United States, Canada
Sponsor
Alliance for Clinical Trials i
NCT05708716 N/A
Recruiting
Diet and Cognitive Training in Hematologic Cancer Survivors
Condition
Cognitive Impairment
Enrollment
80 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05490225 N/A
Recruiting
Access Cannulation Trial II
Condition
Dialysis; Complications
Enrollment
100 pts
Location
United States
Sponsor
Voyager Biomedical
NCT02193841 Phase 3
Recruiting
Simple Bone Cysts in Kids
Condition
Bone Cyst
Enrollment
160 pts
Location
United States, Australia, Canada
Sponsor
The Hospital for Sick Children
NCT05384145 N/A
Recruiting
Implementation Trial to Evaluate a Population Health Combination Intervention to...
Condition
HIV
Enrollment
80 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT04867317 Phase 3
Recruiting
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury ...
Condition
Adult Growth Hormone Deficiency
Enrollment
172 pts
Location
United States
Sponsor
VA Office of Research and Deve
NCT05943535 Phase 3
Recruiting
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progre...
Condition
Progressive Pulmonary Fibrosis
Enrollment
698 pts
Location
United States, Argentina, Australia
Sponsor
United Therapeutics
NCT03180268 Phase 3
Recruiting
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade...
Condition
Grade 2 Meningioma
Enrollment
163 pts
Location
United States, Canada, India
Sponsor
NRG Oncology
NCT06008197 Phase 3
Recruiting
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mort...
Condition
Heart Failure
Enrollment
5,200 pts
Location
United States, Argentina, Australia
Sponsor
Colorado Prevention Center
NCT06616584 Phase 2, Phase 3
Recruiting
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Adva...
Condition
Recurrent Lung Non-Small Cell Carcinoma
Enrollment
378 pts
Location
United States
Sponsor
SWOG Cancer Research Network
NCT07161726 Phase 1, Phase 2
Recruiting
Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial
Condition
Mobility Disability
Enrollment
36 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT05193552 Phase 4
Recruiting
Usage of Spirometry in Managing IgG Therapy in CVID With Airway Disease
Condition
Common Variable Immunodeficiency
Enrollment
22 pts
Location
United States
Sponsor
University of Alabama at Birmi
NCT07051655 N/A
Recruiting
The Effects of Exogenous Ketones on Cognitive Function
Condition
Placebo - Control
Enrollment
45 pts
Location
United States
Sponsor
University of Alabama at Birmi
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology