Medical Condition

cystic fibrosis

Total Trials

11

Recruiting Now

11

Trial Phases

Phase 1, Phase 2, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for cystic fibrosis sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — cystic fibrosis Clinical Trials

How many clinical trials are currently recruiting for cystic fibrosis?

ClinicalMetric currently tracks 11 actively recruiting clinical trials for cystic fibrosis, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 11. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for cystic fibrosis?

cystic fibrosis research spans Phase 1 (2 trials), Phase 2 (2 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a cystic fibrosis clinical trial?

Eligibility criteria for cystic fibrosis trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 3

Top Sponsors

Vertex Pharmaceuticals Incorporated 2 trials

Hospices Civils de Lyon 2 trials

University of British Columbia 2 trials

Assistance Publique - Hôpitaux de Paris 1 trial

University of Pittsburgh 1 trial

Recruiting Clinical Trials

NCT07437105 Phase 1

Recruiting

Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants

Vertex Pharmaceuticals Incorpo...

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NCT06507956

Recruiting

Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis

Hospices Civils de Lyon

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NCT06356246

Recruiting

Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association.

Assistance Publique - Hôpitaux...

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NCT07283770 Phase 1

Recruiting

Evaluation of VX-581 in Healthy Participants and in Participants With Cystic Fibrosis

Vertex Pharmaceuticals Incorpo...

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NCT06296394

Recruiting

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

University of Pittsburgh

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NCT05723445

Recruiting

The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes

Rhode Island Hospital

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NCT04731272 Phase 2

Recruiting

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

University of Pennsylvania

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NCT05279040

Recruiting

Trikafta Exercise Study in Cystic Fibrosis

University of British Columbia

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NCT06413368 Phase 2, Phase 3

Recruiting

Maralixibat in Patients With Cystic Fibrosis and Constipation

Children's Hospital Los Angele...

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NCT06599892

Recruiting

CF Organization of Care in the Era of Highly Effective Modulator.

Hospices Civils de Lyon

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NCT05200429

Recruiting

Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CF

University of British Columbia

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Related Conditions

parenthood status (1) cystic fibrosis related diabetes (1) cystic fibrosis with intestinal manifestations (1) pancreatic insufficiency (1) abnormal glucose tolerance (1) diabetes (1) lung diseases (1) constipation chronic idiopathic (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology